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Critical Care General

Clinical Consensus Recommendations Regarding Non-Invasive Respiratory Support in the Adult Patient with Acute Respiratory Failure Secondary to SARS-CoV-2 infection.

Apr 28, 2020

Coronavirus disease 2019 (COVID-19) is a respiratory tract infection caused by a newly emergent coronavirus, that was first recognized in Wuhan, China, in December 2019. Currently, the World Health Or...

Antimicrobials administration time in patients with suspected sepsis: is faster better? An analysis by propensity score.

Apr 28, 2020

Early use of antimicrobials is a critical intervention in the treatment of patients with sepsis. The exact time of initiation is controversial and its early administration may be a difficult task in c...

A Curious Case of Blastomyces Osteomyelitis.

Apr 28, 2020

Blastomycosis is an uncommon disease caused by the dimorphic fungus, Blastomyces dermatitidis, often found in endemic regions of Midwestern America. It can be found in forested, sandy soils, decaying ...

COVID-19 and its implications for thrombosis and anticoagulation.

Apr 28, 2020

The SARS-CoV-2 coronavirus (COVID-19) induced infection can be associated with a coagulopathy, findings consistent with infection induced inflammatory changes as observed in patients with disseminated...

Application of the Behavioral Indicators of Pain Scale in Patients with Traumatic Brain Injury.

Apr 28, 2020

To develop and psychometrically test the Behavioral Indicators of Pain Scale (ESCID) in patients with traumatic brain injury DESIGN: A prospective observational study to test the psychometric properti...

Patients' recovery after severe TBI is associated with their close relatives' interpersonal functioning: a 12-months prospective cohort study.

Apr 28, 2020

: The aim of this study was to investigate the association between relatives' interpersonal functioning and patients' recovery after severe traumatic brain injury (TBI) across one year in Switzerland....

A Systematic Review of the Incidence, Prevalence, Costs, and Activity/Work Limitations of Amputation, Osteoarthritis, Rheumatoid Arthritis, Back Pain, Multiple Sclerosis, Spinal Cord Injury, Stroke, and Traumatic Brain Injury in the United States: A 2019 Update.

Apr 28, 2020

To present recent evidence on the prevalence, incidence, costs, activity limitations, and work limitations of common conditions requiring rehabilitation.This was a systematic review. Medline (PubMed),...

The single intravenous administration of methylene blue after traumatic brain injury diminishes neurological deficit, blood-brain barrier disruption and decrease in the expression of S100 protein in rats.

Apr 28, 2020

The protective effect of methylene blue (MB) was investigated on the model of focal one-sided traumatic brain injury (TBI) of the sensorimotor cortex region from 1 to 7 days after the injury. TBI caus...

Dendrimer mediated targeted delivery of sinomenine for the treatment of acute neuroinflammation in traumatic brain injury.

Apr 28, 2020

Traumatic brain injury (TBI) is a significant medical problem with limited treatment options and is one of the main causes of life-long disability. Neuroinflammation orchestrated by activated microgli...

Evaluation and Management of Premature Ventricular Complexes.

Apr 28, 2020

Premature ventricular complexes (PVCs) are extremely common, found in the majority of individuals undergoing long-term ambulatory monitoring. Increasing age, a taller height, a higher blood pressure, ...

Contemporary use of balloon aortic valvuloplasty and evaluation of its success in different hemodynamic entities of severe aortic valve stenosis.

Apr 28, 2020

To evaluate outcome assessment of percutaneous balloon aortic valvuloplasty (BAV) in different flow and gradient patterns of severe aortic stenosis (AS).The mean pressure gradient reduction after BAV ...

Proteomic analysis of the cardiac myocyte secretome reveals extracellular protective functions for the ER stress response.

Apr 28, 2020

The effects of ER stress on protein secretion by cardiac myocytes are not well understood. In this study, the ER stressor thapsigargin (TG), which depletes ER calcium, induced death of cultured neonat...

Post-Implantation Syndrome is Not Associated With Mins (Myocardial Injury After Non-Cardiac Surgery) After EVAR.

Apr 28, 2020

Post-implantation syndrome (PIS) is the clinical and biochemical expression of an inflammatory response following endovascular aneurysm repair, with a reported incidence ranging from 2-100%. Although ...

Systematic review and literature appraisal on methodology of conducting and reporting critical-care echocardiography studies: a report from the European Society of Intensive Care Medicine PRICES expert panel.

Apr 28, 2020

The echocardiography working group of the European Society of Intensive Care Medicine recognized the need to provide structured guidance for future CCE research methodology and reporting based on a sy...

Complexity of aortic arch anatomy affects the outcomes of transcarotid artery revascularization versus transfemoral carotid artery stenting.

Apr 28, 2020

Transcarotid artery revascularization (TCAR) has been shown to have half the rates of transient ischemic attack (TIA), stroke and death compared to transfemoral carotid artery stenting (TFCAS). Succes...

Surgical embolectomy in a cat with cardiogenic aortic thromboembolism.

Apr 28, 2020

A seven-year-old, spayed female, domestic longhair cat was referred for management of a sudden aortic thromboembolism (ATE). Echocardiography showed hypertrophic cardiomyopathy with severe left atrial...

Seasonality of postoperative pneumonia after coronary artery bypass grafting: A national inpatient sample study.

Apr 28, 2020

The development of postoperative pneumonia following cardiac surgery is associated with significant morbidity and mortality. However, seasonal variation as a risk factor for the development of postope...

Endovascular therapy provides similar results of bypass graft surgery in the treatment of infrainguinal multilevel arterial disease in patients with chronic limb-threatening ischemia in all GLASS stages.

Apr 28, 2020

To compare the results of concomitant femoropopliteal and infrapopliteal percutaneous angioplasty / stenting (PTA/S) with distal bypass graft surgery (BGS) in patients with chronic limb-threatening is...

Lowering Mortality In Patients With Idiopathic Pulmonary Fibrosis

Apr 24, 2020

A rare disease of unknown etiology, idiopathic pulmonary fibrosis (IPF) is characterized by progressive, irreversible scarring of the lung interstitium leading to a reduction in respiratory function a...

Umbilical artery carbon dioxide decreases the risk for hypoxic-ischemic encephalopathy.

Apr 20, 2020

An accurate biomarker for metabolic acidosis at birth is needed. Our aims were to investigate the link between umbilical artery pCO and the risk for hypoxic-ischemic encephalopathy (HIE) and to compar...

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