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Critical Care General

Intraoperative fluorescence angiography is reproducible and reduces the rate of anastomotic leak after colorectal resection for cancer: a prospective case-matched study.

Apr 20, 2020

Intraoperative fluorescence angiography (IOFA) with indocyanine green provides information on tissue perfusion that may help prevent an anastomotic leak (AL). The aim of this study was to assess the i...

Admission diagnosis and mortality risk prediction in a contemporary cardiac intensive care unit population.

Apr 20, 2020

Critical care risk scores can stratify mortality risk among cardiac intensive care unit (CICU) patients, yet risk score performance across common CICU admission diagnoses remains uncertain.We evaluate...

Interleukin-31 interaction with inflammasome: A promising diagnostic and prognostic panel for early sepsis identification in critically ill patients.

Apr 20, 2020

This case-control study aimed to evaluate the ability to use a panel of IL-31, IL-1ß and NLRP3 to differentiate sepsis from systemic inflammatory response syndrome (SIRS) and to predict septic shock....

Segmentation of cervical intervertebral disks in videofluorography by CNN, multi-channelization and feature selection.

Apr 20, 2020

Dysphagia has a large impact on the society because it is a risk factor of malnutrition and aspiration pneumonia, and therefore, it is necessary to elucidate the entire mechanism of dysphagia. In this...

Chloroquine for SARS-CoV-2: Implications of Its Unique Pharmacokinetic and Safety Properties.

Apr 20, 2020

Since in vitro studies and a preliminary clinical report suggested the efficacy of chloroquine for COVID-19-associated pneumonia, there is increasing interest in this old antimalarial drug. In this ar...

Silver nanoparticles synthesis using Wedelia urticifolia (Blume) DC. flower extract: Characterization and antibacterial activity evaluation.

Apr 20, 2020

Silver nanoparticles (AgNPs), synthesized by green methods with the property to kill microbes, are highly valuable in medical sciences. So, the current study was aimed at using the flower extract of W...

Respiratory Pathogens Associated with Intubated Pediatric Patients following Hematopoietic Cell Transplant.

Apr 20, 2020

We describe organisms found in the respiratory tracts of a multicenter cohort of pediatric hematopoietic cell transplant (HCT) recipients with respiratory failure.Twelve centers contributed up to 25 p...

[The characteristics of morbidity of population older than able-bodied age in the Russian Federation in 2012-2018].

Apr 20, 2020

The indices of population health exhibit tendency to deteriorate with age. The high level of morbidity, prevalence of chronic diseases, polymorbidity, atypical course of disease, continuous rehabilita...

Diagnostic Value of Presepsin for Bacterial Infection in Cirrhosis: A Pilot Study.

Apr 20, 2020

Presepsin (or sCD14) has been identified as a protein whose levels increase specifically in the blood of patients with bacterial infections. In this study, we evaluated the clinical performance of sCD...

Etiological profile of hearing loss amongst Lithuanian pediatric cochlear implant users.

Apr 20, 2020

Congenital sensorineural hearing loss is a heterogeneous disorder; its etiological profile varies between populations. Pathogenic variants of GJB2 gene are the major cause of non-syndromic hearing los...

Pseudo-wound infection after a caesarean section: Case report of unrecognized Pyoderma Gangrenosum.

Apr 20, 2020

Pyoderma Gangrenosum (PG) is a rare auto-inflammatory disease, characterized by painful ulcerative skin-lesions often developing at sites of injury or surgery because of the typical pathergy phenomena...

The roles of NLRP3 inflammasome in bacterial infection.

Apr 20, 2020

The NOD-like receptor (NLR) family pyrin domain-containing 3 (NLRP3) inflammasomes are intracellular protein complexes that orchestrate immune responses through mediating caspase-1 activation, which l...

Group B streptococcal transmission rates as determined by PCR.

Apr 20, 2020

Background Group B Streptococcus (GBS) is a common cause of neonatal sepsis. GBS colonization of the newborn gastrointestinal tract (GIT) may be a critical precursor for late-onset infection. Assessme...

Early life stress increases vulnerability to the sequelae of pediatric mild traumatic brain injury.

Apr 20, 2020

Early life stress (ELS) is a risk factor for many psychopathologies that happen later in life. Although stress can occur in cases of child abuse, studies on non-accidental brain injuries in pediatric ...

Glycogen synthase kinase-3: The missing link to aberrant circuit function in disorders of cognitive dysfunction?

Apr 20, 2020

Elevated GSK-3 activity has been implicated in cognitive dysfunction associated with various disorders including Alzheimer's disease, schizophrenia, type 2 diabetes, traumatic brain injury, major depr...

National Imaging Trends in Pediatric Traumatic Brain Injury and Hydrocephalus.

Apr 20, 2020

CT reduction in favor of rapid sequence MRI to decrease pediatric radiation exposure has varied across institutions. We aim to understand national trends in CT and rapid sequence MRI usage, as well as...

Cathepsin B in neurodegeneration of Alzheimer's disease, traumatic brain injury, and related brain disorders.

Apr 20, 2020

Investigations of Alzheimer's disease (AD), traumatic brain injury (TBI), and related brain disorders have provided extensive evidence for involvement of cathepsin B, a lysosomal cysteine protease, in...

Characteristics and outcome of severe traumatic brain injuries based on occupational status.

Apr 20, 2020

The association of TBI with socioeconomic characteristics of patients has not been studied extensively. The objective of this study was to analyse the differences in injury characteristics and outcome...

High-sensitivity cardiac troponin T 30 days all-come mortality in patients with acute heart failure. A Propensity Score-Matching Analysis Based on the EAHFE Registry. TROPICA4 Study.

Apr 20, 2020

Acute heart failure (AHF) patients with high troponin levels have a worse prognosis. High-sensitive troponin T (hs-TnT) has been used as a tool to stratify prognosis in many scales but always as a qua...

Predicting Functional Outcome Based on Linked Data After Acute Ischemic Stroke: S-SMART Score.

Apr 20, 2020

Prediction of outcome after stroke may help clinicians provide effective management and plan long-term care. We aimed to develop and validate a score for predicting good functional outcome available f...

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