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Critical Care General

An experimental porcine model of invasive candidiasis.

May 15, 2023

Invasive candidiasis (IC) is a severe and often fatal fungal infection that affects critically ill patients. The development of animal models that mimic human disease is essential for advancing our un...

Longitudinal assessment of cardiac parameters through MRI in breast cancer patients treated with anti-HER2 therapy.

May 15, 2023

We evaluated the early changes in left ventricular (LV) volumetric, functional, and tissue characteristics in human epidermal growth factor receptor 2 (HER2)-positive breast cancer patients treated wi...

Experiences of dignity: Age at onset of serious illness matters.

May 15, 2023

Preserving persons' dignity is integral to nursing. More research is needed to explore how a diversity of patients, particularly those that experience illness from a young age, experience dignity.Desc...

Saudi Critical Care Society clinical practice guidelines on the prevention of venous thromboembolism in adults with trauma: reviewed for evidence-based integrity and endorsed by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine.

May 15, 2023

To develop evidence-based clinical practice guidelines on venous thromboembolism (VTE) prevention in adults with trauma in inpatient settings.The Saudi Critical Care Society (SCCS) sponsored guideline...

Necrotizing fasciitis of the chest wall caused by empyema necessitans following tuberculosis: Case report and literature review.

May 08, 2023

Empyema is a serious complication characterized by pus and bacteria in the pleural space which may progress to necrosis, cavitation, or fistulas in the thoracic cavity. Infection and trauma are the co...

Successful use of subcutaneous anakinra in hemophagocytic lymphohistiocytosis precipitated by candidiasis in a patient with systemic lupus erythematosus: A case report and description of a novel therapeutic regimen.

May 08, 2023

Hemophagocytic lymphohistiocytosis (HLH) is a rare and often fatal condition characterized by inappropriate immune system activation leading to a "cytokine storm", and ultimately resulting in end-orga...

AT 1 inhibition mediated neuroprotection after experimental traumatic brain injury is dependent on neutrophils in male mice.

May 08, 2023

After traumatic brain injury (TBI) cerebral inflammation with invasion of neutrophils and lymphocytes is a crucial factor in the process of secondary brain damage. In TBI the intrinsic renin-angiotens...

Emulating target trials comparing early and delayed intubation strategies.

May 08, 2023

Whether intubation should be initiated early in the clinical course of critically ill patients remains a matter of debate. Results from prior observational studies are difficult to interpret because o...

Assessing Decision-Making Algorithm for Collecting Blood Culture in the ICU

May 05, 2023

The following is a summary of “Assessing a standardized decision-making algorithm for blood culture collection in the intensive care unit,” published in the February 2023 issue of Critical Care by...

Interpretable and Accurate Prediction of ICU-acquired AKI

May 04, 2023

The following is a summary of "Accurate and interpretable prediction of ICU-acquired AKI ," published in the February 2023 issue of Critical Care by Schwager et al. Two parsimonious algorithms ...

Revolutionizing ARDS Detection: The Power of Reverse-Triggering Neural Networks

May 03, 2023

The following is a summary of “Reverse triggering neural network and rules-based automated detection in acute respiratory distress syndrome,” published in the January 2023 issue of  Critical Care...

PEEP in COVID-19 Patients: A Retrospective Study on RV Dysfunction

May 01, 2023

The following is a summary of "Optimal positive end-expiratory pressure reduces right ventricular dysfunction in COVID-19 patients on venovenous extracorporeal membrane oxygenation: A retrospective si...

Furosemide exacerbated the impairment of renal function, oxygenation and medullary damage in a rat model of renal ischemia/reperfusion induced AKI.

May 01, 2023

Perioperative acute kidney injury (AKI) caused by ischemia-reperfusion (IR) is a significant contributor to mortality and morbidity after major surgery. Furosemide is commonly used in postoperative pa...

Skin biopsy in adult patients with meningococcal purpura fulminans: a multicenter retrospective cohort study.

May 01, 2023

Neisseria meningitidis is the leading responsible bacterium of Purpura Fulminans (PF) accounting for two thirds of PF. Skin biopsy is a simple and minimally invasive exam allowing to perform skin cult...

Does Preterm Status Hinder the Timely Diagnosis of Intestinal Atresia?

May 01, 2023

Intestinal atresia is one of the most common causes of bowel obstruction in newborns. Unfortunately, this diagnosis is often missed or delayed in extremely preterm infants because of complications of ...

Systematic review of economic evaluations for paediatric pulmonary diseases.

May 01, 2023

Paediatric pulmonary diseases are the leading causes of mortality amongst children under five globally. Economic evaluations (EEs) seek to guide decision-makers on which health care interventions to a...

Case report: therapeutic monitoring of vancomycin in an acute liver failure patient with anuria under high-flow continuous hemodiafiltration.

May 01, 2023

High-flow continuous hemodiafiltration (HF-CHDF) combines diffusive and convective solute removal and is employed for artificial liver adjuvant therapy. However, there is no report on dosage planning ...

Early diagnosis leading to improvement of critical illness polyneuropathy associated with severe Staphylococcus aureus infection in a patient on hemodialysis.

May 01, 2023

Critical illness polyneuropathy (CIP) is a very rare complication of sepsis and multi-organ failure. Herein, we report the first case of CIP reported in a patient on maintenance hemodialysis, who impr...

Registry Data Show Complication Rates and Cost in Revision Hip Arthroplasty.

May 01, 2023

Revision THA (rTHA) places a burden on patients, surgeons, and health care systems because outcomes and costs are less predictable than primary THA. The purposes of this study were to define indicatio...

Prenatal diagnosis of isolated coronary artery fistula: systematic review, analysis of perinatal prognostic factors and case report.

May 01, 2023

Isolated coronary artery fistula (CAF) is a rare entity in which evidence for both prognosis and need for perinatal treatment is lacking. We aim to evaluate the characteristics, evolution and perinata...

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