Critical Care General
Apr 06, 2020
This study used constitutive CD226 gene knockout (KO) mice as a model to investigate the functions and mechanisms of CD226 in megakaryocyte (MK) maturation and platelet activation. Although CD226 defi...
Apr 06, 2020
Sepsis is a potentially fatal complication of infections and there are currently no effective therapeutic options for severe sepsis. In this study, we revealed the secretion mechanism of transforming ...
Apr 06, 2020
The aim: To conduct an analysis of the complex treatment of severe forms of rectal abscesses complicated by NF.Materials and methods: The results of treatment in 471 patients with deep forms of RA was...
Apr 06, 2020
Curcumin derivatives have been shown to inhibit replication of human influenza A viruses (IAVs). However, it is not clear whether curcumin and its derivatives can inhibit neuraminidase (NA) of influen...
Apr 06, 2020
Autosomal dominant hyper IgE syndrome (AD-HIES) caused by STAT3 gene mutation is a rare primary immunodeficiency disease. To better understand the disease, we described the clinical characteristics of...
Apr 06, 2020
Avian influenza A(H5N6) keeps evolving, causing outbreaks in birds and sporadic infections in human. Here we report a fatal pediatric infection caused by a novel reassortant H5N6 virus. The patient wa...
Apr 06, 2020
Non-alcoholic fatty liver disease (NAFLD) and human immunodeficiency virus (HIV) are independently associated with cardiovascular disease (CVD). However, the factors associated with NAFLD in persons l...
Apr 06, 2020
In ENSURE-AF (NCT02072434), the oral Factor Xa inhibitor edoxaban showed similar efficacy and safety vs enoxaparin-warfarin in patients undergoing electrical cardioversion of nonvalvular atrial fibril...
Apr 06, 2020
Prasugrel was approved at a lower dose in 2014 in Japan than in the West because East Asian patients are considered more susceptible to bleeding than Western patients. However, real-world outcomes wit...
Apr 06, 2020
Occlusive atherosclerotic disease of the anterior cerebral circulation is one of the most common causes of anterior circulation ischemia and stroke. Treatment options include medical therapies (includ...
Apr 06, 2020
The early recognition of invasive bacterial infections (IBI) in children can be difficult. Clinically it is often challenging to differentiate between the early stages of an IBI and a benign self-limi...
Apr 06, 2020
Ceftobiprole is a new therapeutic option for bacterial pneumonia, with activity against most antimicrobial resistant gram-positive cocci, including methicillin-resistant Staphylococcus aureus. Data on...
Apr 06, 2020
The decision to perform a total knee arthroplasty (TKA) on a previously infected knee is made complicated by the higher risk for both a periprosthetic joint infection (PJI) and early failure. There is...
Apr 06, 2020
We review a series of isolated septic facet joints (ISFJ) that present as a distinct clinical entity compared with spondylodiscitis. We aim to raise awareness that septic facet joints are not a rare e...
Apr 06, 2020
To study the epidemiology of hospitalized serious infections in people with gout.We identified people with gout hospitalized with a primary diagnosis of pneumonia, sepsis/bacteremia, urinary tract inf...
Apr 06, 2020
Determine the frequency of polytraumatized pediatric patients involved in motorcycle accidents treated at the Pediatric Hospital of Sinaloa between 2015 and 2017, as well as to determine the frequency...
Apr 06, 2020
Dipeptidyl peptidase-4 inhibitors (or gliptins), a class of antidiabetic drugs, have recently been shown to have protective actions in the central nervous system. Their cellular and molecular mechanis...
Apr 06, 2020
Management of panfacial fractures is critical and often difficult in adults; however, there is little to no literature regarding these fractures in the pediatric population. In this study, we present ...
Apr 06, 2020
Decreases in energy metabolism following traumatic brain injury (TBI) are attributed to impairment of glycolytic flux and oxidative phosphorylation. Glucose utilization post-TBI is decreased while adm...
Apr 06, 2020
To explore the potential utility of head acceleration event (HAE) measurements to augment identification of players for further concussion screening in non-helmeted contact sport.Prospective observati...