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Critical Care General

Role of dipstick proteinuria for predicting cardiovascular events: a Japanese cardiovascular hospital database analysis.

Apr 06, 2020

Initial screening for proteinuria by urine dipstick test (UDT) may be useful for predicting clinical outcomes. The Shinken Database includes all the new patients visiting the Cardiovascular Institute ...

The prognostic impact of the controlling nutritional status (CONUT) score in patients undergoing cardiovascular surgery.

Apr 06, 2020

Various postoperative predictive markers following cardiovascular surgery have been examined for use in the current aging population. The controlling nutritional status (CONUT) score, which is advocat...

The Association of ICU Acuity with Adherence to ICU Evidence-Based Processes of Care.

Apr 06, 2020

Admission to high-acuity intensive care units (ICUs) has been associated with improved outcomes compared to low-acuity ICUs, although the mechanism for these findings is unclear.Do high-acuity ICUs mo...

Mid-term results after simultaneous carotid artery stenting and cardiac surgery.

Apr 06, 2020

The presence of carotid artery disease is known risk factor for perioperative stroke in cardiac surgery. The optimal management of patients with concomitant heart and carotid artery disease is not kno...

Efficacy of continuous positive airway pressure (CPAP) in the prevention of cardiovascular events in patients with obstructive sleep apnea: Systematic review and meta-analysis.

Apr 06, 2020

Obstructive sleep apnea (OSA) commonly occurs in patients with increased cardiovascular (CV) risk, and continuous positive airway pressure (CPAP) is the preferred therapy for these patients. The aim o...

The Design of and Rationale for the Effect of Perioperative Inhaled Tiotropium for Patients with Chronic Obstructive Pulmonary Disease in Esophageal Cancer Surgery (EPITOPE): an Open-Label, Randomized, Parallel-Group Study.

Apr 06, 2020

Pneumonia is one of the most frequently occurring complications after esophagectomy and is associated with increased operative mortality. Chronic obstructive pulmonary disease (COPD) is known to be a ...

Beyond heart failure and ischemic heart disease: a scoping review of novel uses of ivabradine in adults.

Apr 06, 2020

Ivabradine lowers heart rate by inhibiting the hyperpolarization-activated current in pacemaker cells, and its use for the treatment of heart failure (HF) and ischemic heart disease (IHD) is well desc...

Mortality rate of COVID-19 patients on ventilators

Mar 30, 2020

Written by Physician's Weekly Blogger, Skeptical Scalpel Although at the time I wrote this over 33,000 people had died from COVID 19 infections worldwide, the numbers of patients dying in intensive...

Intraoperative Neurophysiologic Monitoring Correlates with Neurologic Outcome After Endovascular and Surgical Treatment of a Cervical Arteriovenous Malformation.

Mar 30, 2020

 The treatment of spinal intramedullary arteriovenous malformations (AVMs) presents the risk of spinal cord ischemia because of the vascular nidus and their feeding arteries involving and supplying ...

The αC helix of TIRAP holds therapeutic potential in TLR-mediated autoimmune diseases.

Mar 30, 2020

Despite being crucial for combating microbes, paradoxical Toll-like receptors (TLRs) signaling have been associated with the aggravation of multiple immune disorders such as systemic lupus erythematos...

HDAC6 promotes sepsis development by impairing PHB1-mediated mitochondrial respiratory chain function.

Mar 30, 2020

This study was aimed at investigating the regulation of mitochondrial function by histone deacetylase 6 (HDAC6) and the role of HDAC6 in the development and progression of sepsis.HDAC6 downregulated P...

Down-regulation of lncRNA CASC9 aggravates sepsis-induced acute lung injury by regulating miR-195-5p/PDK4 axis.

Mar 30, 2020

Long non-coding RNA (lncRNA) cancer susceptibility candidate 9 (CASC9) is reported to be linked to cancers. This research aims to explore the role and possible mechanism of CASC9 in lung injury induce...

[Improved patient safety through a clinical decision support system in laboratory medicine].

Mar 30, 2020

Laboratory diagnostics are essential for diagnosis, initiation of therapy, and monitoring of patients. Laboratory results that are overlooked or incorrectly interpreted lead to adverse events and enda...

Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: an observational cohort study.

Mar 30, 2020

Since December, 2019, an outbreak of coronavirus disease 2019 (COVID-19) has spread globally. Little is known about the epidemiological and clinical features of paediatric patients with COVID-19.We re...

Allograft hemorrhage as a manifestation of carbapenem-resistant Klebsiella pneumonia infection in kidney transplant recipients: Case series.

Mar 30, 2020

Carbapenem-resistant Klebsiella pneumonia (CRKP) infections have been a concerning threat, especially in organ transplant patients with very high mortality. Allograft hemorrhage associated with CRKP i...

Lefamulin: A Novel Semisynthetic Pleuromutilin Antibiotic for Community-Acquired Bacterial Pneumonia.

Mar 30, 2020

Community-acquired bacterial pneumonia (CABP) remains a significant cause of morbidity and mortality worldwide. Antimicrobial resistance, including in pathogens that cause CABP, continues to spread at...

Clinical analysis of pregnant women with 2019 novel coronavirus pneumonia.

Mar 30, 2020

To evaluate the pregnant women infected with coronavirus disease 2019 (COVID-19) and provide help for clinical prevention and treatment.All 5 cases of pregnant women confirmed COVID-19 were collected ...

Aspirin Resistance Affects Medium-Term Recurrent Vascular Events after Cerebrovascular Incidents: A Three-Year Follow-up Study.

Mar 30, 2020

: The aim of this prospective, a three-year follow-up study, was to establish the role of high on-treatment platelet reactivity (HTPR) in predicting the recurrence of vascular events in patients after...

Isolated pulmonary embolism is associated with a high risk of arterial thrombotic disease - Results from the VTEval Study.

Mar 30, 2020

Isolated PE is associated with a higher burden of atherosclerotic disease than other manifestations of venous thromboembolism (VTE).We hypothesized that the presence of isolated PE may signal a chroni...

Coronavirus Disease 2019 (COVID-19) Pandemic and Pregnancy.

Mar 30, 2020

The current coronavirus disease 2019 (COVID-19) pneumonia pandemic, caused by the severe acute respiratory syndrome 2 (SARS-CoV-2) virus, is spreading globally at an accelerated rate, with a basic rep...

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