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Critical Care General

Vitamin C May Reduce Ventilation Time in Critically Ill Patients

Mar 29, 2020

Review shows vitamin C can shorten the duration of mechanical ventilation by an average of 25 percent The administration of vitamin C shortens the length of mechanical ventilation in critically i...

FDA Warns of Defective EpiPen Dangers

Mar 25, 2020

WEDNESDAY, March 25, 2020 (HealthDay News) -- Certain types of EpiPens and their generic counterparts may fail or delay injection of lifesaving epinephrine for severe allergic reactions, the U.S. Food...

A retrospective cohort study to assess PET-CT findings and clinical outcomes in Takayasu arteritis: does 18F-fluorodeoxyglucose uptake in arteries predict relapses?

Mar 23, 2020

The objective of this study is to investigate the use of PET-CT scan with 18F-fluorodeoxyglucose (18F-FDG) as a method to predict outcomes in patients with Takayasu arteritis (TAK), as well as to anal...

Prognostic role of moderate functional tricuspid regurgitation in length of hospitalization in patients undergoing isolated coronary artery bypass grafting.

Mar 23, 2020

Functional tricuspid regurgitation (FTR) is defined as abnormal systolic tricuspid leakage with normal valve structures, and its prognostic role and management in patients with left-heart valve diseas...

Plasma osteopontin levels in patients with acute kidney injury requiring dialysis: a study in a tertiary care institute in South India.

Mar 23, 2020

Osteopontin (OPN) is evolving as a novel biomarker of injury, overall survival and renal outcome in critically ill patients with acute kidney injury (AKI), requiring renal replacement therapy.We perfo...

Association of Early-Onset Sepsis and Vitamin D Deficiency in Term Neonates.

Mar 23, 2020

To determine if vitamin D status is affected in term neonates with early onset sepsis and its association with outcome.Study was done at a level 3 neonatal unit on 140 neonates. Term neonates with ear...

Fibrin exposure triggers αIIbβ3-independent platelet aggregate formation, ADAM10 activity and glycoprotein VI shedding in a charge-dependent manner.

Mar 23, 2020

Collagen and fibrin engagement and activation of glycoprotein (GP) VI induces proteolytic cleavage of the GPVI ectodomain generating shed soluble GPVI (sGPVI). Collagen-mediated GPVI shedding requires...

Engineered silver nanoparticle (Ag-NP) behaviour in domestic on-site wastewater treatment plants and in sewage sludge amended-soils.

Mar 23, 2020

Untreated sludge from small-scale on-site domestic wastewater treatment systems (septic tanks) was spiked with 20, 60 and 100 nm silver nanoparticles (Ag-NPs) to investigate Ag-NP behaviour in these...

Neurological outcomes of congenital Zika syndrome in toddlers and preschoolers: a case series.

Mar 23, 2020

Congenital Zika syndrome causes a spectrum of neurological symptoms with varying effects on function that require different therapeutic strategies. To date, this spectrum of effects and its clinical i...

The characteristics and clinical value of chest CT images of novel coronavirus pneumonia.

Mar 23, 2020

To investigate the characteristics and clinical value of chest computed tomography (CT) images of novel coronavirus pneumonia (NCP).Clinical data and CT images of 80 cases of NCP were collected. The c...

Postoperative Pneumonia after Craniotomy: Incidence, Risk Factor, Prediction with Nomogram.

Mar 23, 2020

Postoperative pneumonia is the third most common complication in surgical patients. However, little is known regarding pneumonia after craniotomy, which is the most commonly performed surgery in the n...

Dexmedetomidine alleviates sleep-restriction-mediated exaggeration of postoperative immunosuppression via splenic TFF2 in aged mice.

Mar 23, 2020

Major abdominal procedures could induce dysfunction in the immune system and lead to postoperative immunosuppression. Sleep dysfunction is associated with impaired immune activity. However, the effect...

Differences of TNF-α, IL-6 and Gal-3 in lobar pneumonia and bronchial pneumonia caused by mycoplasma pneumoniae.

Mar 23, 2020

To investigate the differences of tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and galectin-3 concentrations in lobar pneumonia and bronchopneumonia induced by mycoplasma pneumoniae (MP) in...

Outcome of inter-hospital transfer versus direct admission for primary percutaneous coronary intervention: An observational study of 25,315 patients with ST-elevation myocardial infarction from the London Heart Attack Group.

Mar 23, 2020

In patients with ST-segment elevation myocardial infarction (STEMI), mortality is directly related to time to reperfusion with guidelines recommending patients be delivered directly to centres for pri...

Does Resting Cardiac Power Index Affect Survival Post Transcatheter Aortic Valve Replacement?

Mar 23, 2020

Cardiac power index (CPI) is an integrative hemodynamic measure of cardiac pumping capability and is the product of the simultaneously measured mean arterial pressure and the cardiac output. We assess...

Mortality and recurrent vascular events after first incident stroke: a 9-year community-based study of 0·5 million Chinese adults.

Mar 23, 2020

Stroke is a leading cause of death and disability worldwide. Despite considerable improvements in diagnosis and treatment, little is known about the short-term and long-term prognosis after a first st...

Diagnostic test accuracy of serum measurement of procalcitonin and C-reactive protein for bone and joint infection in children and adolescents: a systematic review protocol.

Mar 23, 2020

The objective of this review is to synthesize the best available evidence for the diagnostic test accuracy of procalcitonin (PCT) compared to C-reactive protein (CRP) in diagnosing osteomyelitis (OM) ...

Rapid and Broad Immune Efficacy of a Recombinant Five-Antigen Vaccine against Infection in Animal Models.

Mar 23, 2020

() is a leading cause of both healthcare-and community-associated infections globally, which result in severe disease and readily developing antibiotic resistance. Developing an efficacious vaccine a...

Hemophagocytic syndrome with severe sepsis caused by Capnocytophaga canimorsus.

Mar 23, 2020

Capnocytophaga canimorsus, commonly transmitted by dog bites, can cause severe sepsis, and the mortality rate is very high. We experienced a case of hemophagocytic lymphohistiocytosis (HLH) complicate...

Targeting of G-protein coupled receptors in sepsis.

Mar 23, 2020

The Third International Consensus Definitions (Sepsis-3) define sepsis as life-threatening multi-organ dysfunction caused by a dysregulated host response to infection. Sepsis can progress to septic sh...

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