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Critical Care General

Epidemiology and effective pertussis vaccination of hospitalized children at Vietnam National Children's Hospital, 2015 - 2018.

Mar 18, 2020

Evaluate effect and costs of pertussis vaccination at Vietnam national children's hospital.Pertussis cases were defined by positive laboratory tests of children under 5 years January 2015 - June 2018,...

Circ_0038467 regulates lipopolysaccharide-induced inflammatory injury in human bronchial epithelial cells through sponging miR-338-3p.

Mar 18, 2020

Pneumonia is a common acute lower respiratory infection in children and elders. Circular RNAs (circRNAs) have recently been uncovered to play important roles in pneumonia. However, the function and me...

Uncovering sex-specific mechanisms of action of testosterone and redox balance.

Mar 18, 2020

The molecular and pharmacological manipulation of the endogenous redox system is a promising therapy to limit myocardial damage after a heart attack; however, antioxidant therapies have failed to full...

Associations of Serum Dickkopf-1 and Sclerostin With Cardiovascular Events: Results From the Prospective Bruneck Study.

Mar 18, 2020

Background Dickkopf-1 and sclerostin have been implicated in atherosclerosis and vascular calcification. We aimed to quantify the association of their serum levels with incident cardiovascular disease...

Risk of major cardiovascular and neurologic events with obstructive sleep apnea among patients with atrial fibrillation.

Mar 18, 2020

Obstructive sleep apnea (OSA) is a known risk factor for atrial fibrillation (AF). However, it remains unclear whether OSA is independently associated with worse cardiovascular and neurological outcom...

Clinical Relevance and Molecular Pathogenesis of the Emerging Serotypes 22F and 33F of in Spain.

Mar 18, 2020

is the main bacterial cause of respiratory infections in children and the elderly worldwide. Serotype replacement is a frequent phenomenon after the introduction of conjugated vaccines, with emerging...

Integration Analysis of mA-SNPs and eQTLs Associated With Sepsis Reveals Platelet Degranulation and Infection are Mediated by mA mRNA Methylation.

Mar 18, 2020

Sepsis is a major threat with high mortality rate for critically ill patients. Response to pathogen infection by the host immune system is a key biological process involved in the onset and developmen...

Single-cell transcriptomics reveals the alteration of peripheral blood mononuclear cells driven by sepsis.

Mar 18, 2020

Sepsis is a serious systemic inflammatory response syndrome caused by infection, with an extremely high mortality rate. Peripheral blood mononuclear cells (PBMCs) played a key role in the immune respo...

Risk Factors and Molecular Epidemiology of Complicated Intra-Abdominal Infections With Carbapenem-Resistant Enterobacteriaceae: A Multicenter Study in China.

Mar 18, 2020

Carbapenem-resistant Enterobacteriaceae (CRE) infections are associated with poor patient outcomes. Data on risk factors and molecular epidemiology of CRE in complicated intra-abdominal infections (cI...

Development and validation of a nomogram for predicting late-onset sepsis in preterm infants on the basis of thyroid function and other risk factors: Mixed retrospective and prospective cohort study.

Mar 18, 2020

Preterm birth and infection are common causes of neonatal death. In this study, we aimed to develop a nomogram for assessing the individual prior probability of late-onset sepsis on the basis of risk ...

Could a massive open online course be part of the solution to sport-related concussion? Participation and impact among 8368 registrants.

Mar 18, 2020

A massive open online course (MOOC) has the potential to help address the public health burden of concussion across all levels of sport and leisure activities. The main objectives of this study were t...

Combined Therapy Potential of Apocynin and Tert-butylhydroquinone as a Therapeutic Agent to Prevent Secondary Progression to Traumatic Brain Injury.

Mar 18, 2020

Traumatic brain injury is caused by physical collision (primary injury). It changes the brain's biochemistry and disturbs the normal brain function such as memory loss and consciousness disturbance (s...

Isolated Infarction of the Splenium: A Rare Presentation of Mild Head Injury.

Mar 18, 2020

Posttraumatic cerebral infarction (PTCI) is a devastating complication of traumatic brain injury. It is usually seen in patients with moderate-to-severe head injury with a reported incidence of 1.9%-1...

Effects of Preinjury and Postinjury Exposure to Caffeine in a Rat Model of Traumatic Brain Injury.

Mar 18, 2020

Lethal apnea is a significant cause of acute mortality following a severe traumatic brain injury (TBI). TBI is associated with a surge of adenosine, which also suppresses respiratory function in the ...

[Prognostic factors and profile in traumatic brain injury in the paediatric age].

Mar 18, 2020

Traumatic brain injury (TBI) is a common cause of death and disability in the paediatric population, although the literature on the Spanish population is scarce. From the perspective of early vulnerab...

[Predictive factors of early readmission and mortality in patients with heart failure hospitalized in the Department of Internal Medicine of the San Carlos University Hospital, Spain].

Mar 18, 2020

Heart failure (HF) is a health problem in Spain where the prevalence rate for this disease is correlated with aging. Heart failure-related mortality and hospital readmissions are high. The purpose of ...

Pulmonary vasodilation in acute pulmonary embolism - a systematic review.

Mar 18, 2020

Acute pulmonary embolism is the third most common cause of cardiovascular death. Pulmonary embolism increases right ventricular afterload, which causes right ventricular failure, circulatory collapse ...

Diagnostic Utility of N-terminal pro-Brain Natriuretic Peptide and C-reactive Protein in Diagnosing Heart Failure in Patients with Acute Hypoxemic Respiratory Failure.

Mar 18, 2020

Introduction Shortness of breath is a leading cause of intensive care unit (ICU) admissions and is multifactorial. Acute hypoxemic respiratory failure due to heart failure is one of the leading causes...

Variability in expiratory flow requirements among oscillatory positive expiratory pressure.

Mar 18, 2020

Oscillatory positive expiratory pressure (OPEP) devices facilitate secretion clearance by generating positive end expiratory pressure. However, different device designs may produce different levels of...

The Association between Chronic Conditions, End-of-Life Health Care Use, and Documentation of Advance Care Planning among Patients with Cancer.

Mar 18, 2020

Multiple chronic conditions (MCCs) are associated with increased intensity of end-of-life (EOL) care, but their effect is not well explored in patients with cancer. We examined EOL health care inten...

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