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Critical Care General

Hypothermia but not NMDA receptor antagonism protects against stroke induced by distal middle cerebral arterial occlusion in mice.

Mar 04, 2020

Excitotoxicity mediated by the N-methyl-D-aspartate receptor (NMDAR) is believed to be a primary mechanism of neuronal injury following stroke. Thus, many drugs and therapeutic peptides were developed...

Surgical mitral plasticity for chronic ischemic mitral regurgitation.

Mar 04, 2020

The outcome of mitral valve (MV) repair for chronic ischemic mitral regurgitation (IMR) is suboptimal, due to the high recurrence rate of moderate or severe mitral regurgitation (MR) during follow-up....

Recanalization using direct stenting before bowel resection for acute-on-chronic superior mesenteric artery occlusion: A case report.

Mar 04, 2020

Acute-on-chronic mesenteric ischemia (ACMI) refers to acute mesenteric ischemia (AMI) developing in a patient displaying typical symptoms of chronic mesenteric ischemia (CMI). Delayed treatment can ca...

Effects of transportation noise and particulate matter on the cardiovascular system: What is the new evidence?

Mar 04, 2020

Several decades of research provides compelling evidence that exposure to air pollution causes various diseases. Time series studies in Europe and the USA examined the short term effects on mortality ...

Early life neuroimmune challenge protects the brain after sepsis in adult rats.

Mar 04, 2020

Evidences has suggested that in the early life the innate immune system presents plasticity and the time and dose-adequate stimuli in this phase may program long-lasting immunological responses that p...

Gram-negative septic thrombosis in critically ill patients: A retrospective case-control study.

Mar 04, 2020

Few data are presently available on Gram-negative bacilli septic thrombosis (GN-ST) in intensive care unit (ICU) patients.Retrospective case-control study (matched 1:3) performed on ICU patients with ...

Challenges in developing a consensus definition of neonatal sepsis.

Mar 04, 2020

Sepsis remains a leading cause of morbidity and mortality in the neonatal population, and at present, there is no unified definition of neonatal sepsis. Existing consensus sepsis definitions within pa...

Lethal fishing hook penetration and line entanglement in an adult bottlenose dolphin (Tursiops aduncus).

Mar 04, 2020

The carcass of a 15-year-old female Bottlenose dolphin (Tursiops aduncus) was retrieved from the Port River near Adelaide, South Australia, Australia. The animal was emaciated with five thick nylon fi...

Relation Between Chest CT Findings and Clinical Conditions of Coronavirus Disease (COVID-19) Pneumonia: A Multicenter Study.

Mar 04, 2020

The increasing number of cases of confirmed coronavirus disease (COVID-19) in China is striking. The purpose of this study was to investigate the relation between chest CT findings and the clinical c...

Antimicrobial Susceptibility Patterns of spp. Strains Isolated from Water Systems in Morocco.

Mar 04, 2020

is a waterborne pathogen that causes a severe form of pneumonia called Legionnaires' diseases, which is normally acquired by inhalation of aerosols containing originating from natural and man-made w...

Pretreatment of nafithromycin attenuates inflammatory response in murine lipopolysaccharide induced acute lung injury.

Mar 04, 2020

Acute respiratory distress syndrome following an acute lung injury (ALI) is a life threatening inflammatory condition predominantly characterized by vascular protein leakage, neutrophil recruitment an...

Levels of Blood Biomarkers among Patients with Myocardial Infarction in Comparison to Control Group.

Mar 04, 2020

Myocardial infarction (MI) as a term for a heart attack happens due to reduced blood flow to heart myocardium and lack of oxygen supply caused by plaques in the interior walls of coronary arteries. Wi...

Association between fluid creep and infection in burned children: A cohort study.

Mar 04, 2020

Aggressive fluid resuscitation has been extensively discussed after the establishment of fluid creep phenomenon as a morbidity and mortality factor in burn children. Sepsis is currently the leading ca...

Paraspinal Fat Stranding as an Unexpected Finding on Body Computed Tomography: A Key to Early Detection of Spinal Osteomyelitis.

Mar 04, 2020

At present, early detection of spinal osteomyelitis is a challenge. Patients may present with non-specific symptoms and diagnostic imaging studies may be obtained for seemingly unrelated complaints. P...

Three-valve endocarditis in a patient with bioprosthetic aortic valve replacement and intravenous drug use: a case report.

Mar 04, 2020

Here, we outline the case of a US Veteran's Health Administration (VA) patient with a history of recent bioprosthetic aortic valve replacement (AVR) and recent intravenous drug use (IVDU) who was foun...

Nocardiosis in patients with nephrotic syndrome: a retrospective analysis of 11 cases and a literature review.

Mar 04, 2020

We evaluated the clinical manifestations and outcomes of nocardiosis, a rare opportunistic infection that occurs in patients with nephrotic syndrome.The records of NS patients with nocardiosis in a si...

Double-faced implication of CD4 Foxp3 regulatory T cells expanded by acute dengue infection via TLR2/MyD88 pathway.

Mar 04, 2020

Dengue infection causes dengue fever (DF) and dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS). CD4 Foxp3 Tregs are expanded in patients during dengue infection, and appear to be associated wi...

Coherence between sleep detection by actigraphy and polysomnography in a multi-center, in-patient cohort of individuals with traumatic brain injury.

Mar 04, 2020

Sleep is increasingly recognizes as a crucial component to rapid and successful rehabilitation, especially from traumatic brain injuries (TBI). Assessment of longitudinal patterns of sleep in a hospit...

Acute alcohol intoxication as a confounding factor for mild traumatic brain injury.

Mar 04, 2020

Acute alcohol intoxication is universally considered a risk factor for traumatic brain injury (TBI), therefore an indication for head CT scan. There is no evidence in the literature for this attitude....

Sideline Concussion Assessment: The Current State of the Art.

Mar 04, 2020

More than 200 million American adults and children participate in organized physical activity. Growing awareness has highlighted that concussion, especially when repeated, may be associated with prolo...

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