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Critical Care General

Cardiac protection of Bauhinia championii against reperfusion injury.

Feb 18, 2020

This study aims to investigate the protective effects of the Bauhinia championii (BC) against ischemia/reperfusion (I/R)-induced injury in an isolated heart model. Langendorff-perfused C57BL/6JNarl mi...

Data-driven discovery of changes in clinical code usage over time: a case-study on changes in cardiovascular disease recording in two English electronic health records databases (2001-2015).

Feb 18, 2020

To demonstrate how data-driven variability methods can be used to identify changes in disease recording in two English electronic health records databases between 2001 and 2015.Repeated cross-sectiona...

The First Disease X is Caused by a Highly Transmissible Acute Respiratory Syndrome Coronavirus.

Feb 18, 2020

Based on the announcement of the World Health Organization (WHO) in 2018, the Wuhan pneumonia caused by an unknown etiology should be recognized as the first Disease X. Later, the pathogen was identif...

Prophylactic use of acid suppressants in adult acutely ill hospitalised patients: a systematic review with meta-analysis and trial sequential analysis.

Feb 18, 2020

Acutely ill patients are at risk of stress-related gastrointestinal bleeding and prophylactic acid suppressants are frequently used. In this systematic review, we assessed the effects of stress ulcer ...

[Inhibitors of RAS Might Be a Good Choice for the Therapy of COVID-19 Pneumonia].

Feb 18, 2020

The novel coronavirus 2019 (COVID-19) infected patients by binding human ACE2, leading to severe pneumonia and highly mortality rate in patients. At present, there is no definite and effective treatme...

The Dutch influenza vaccination policy and medication use, outpatient visits, hospitalization and mortality at age 65.

Feb 17, 2020

Our objective was to obtain estimates of the impact of the Dutch vaccination programme on medication use, outpatient visits, hospitalization and mortality at age 65.We linked population-wide mortality...

[Clinical features of 2019 novel coronavirus pneumonia in the early stage from a fever clinic in Beijing].

Feb 17, 2020

To summarize and analyze the clinical and imaging characteristics of patients with 2019 novel coronavirus pneumonia in the early stage in Beijing. A retrospective analysis of clinical and imaging da...

Hyperbaric oxygen (HBO) therapy as an effective approach to the treatment of patients with severe idiopathic sudden sensorineural hearing loss.

Feb 13, 2020

The potential etiology of idiopathic sudden sensorineural hearing loss (ISSNHL) is cochlear ischemia, therefore, hyperbaric oxygen (HBO) therapy is a promising treatment, particularly in patients wit...

Quantitative analysis of revascularization in ischemic moyamoya disease via whole-brain computed tomography perfusion: A retrospective single-center study.

Feb 13, 2020

Ischemic moyamoya disease (MMD) can be treated with the revascularization of superficial temporal artery to middle cerebral artery (STA-MCA) bypass combined with encephalo-duro-arterio-myo-synangiosis...

Potential Therapeutic Application of Zinc Oxide Nanoflowers in Cerebral Ischemia Rat Model Through Neuritogenic and Neuroprotective Properties.

Feb 13, 2020

Neuritogenesis, a complex process of sprouting of neurites, plays vital role in structural and functional restoration of cerebral ischemia injured neuronal tissue. Practically, there is no effective l...

Sequential changes of NLRP3 inflammasome activation in sepsis and its relationship with death.

Feb 13, 2020

Inflammasomes are recognized as key components of the innate immune response in sepsis. We aimed to describe the transcriptional expression of nucleotide-binding domain, leucine-rich repeat-containing...

Value of Serum Uncoupling Protein-2 Level for Patients with Sepsis

Feb 13, 2020

To investigate the potential utility of serum uncoupling protein-2 (UCP2) level as a biomarker in septic patients.Critically ill patients with diagnoses of sepsis - sepsis non-shock group (n = 20)...

Long-term mortality and outcome in hospital survivors of septic shock, sepsis, and severe infections: The importance of aftercare.

Feb 13, 2020

Patients with severe infections and especially sepsis have a high in-hospital mortality, but even hospital survivors face long-term sequelae, decreased health-related quality of life, and high risk of...

Free hospitalization for acute respiratory infections in children: what effect and how much does it cost for Armenia?

Feb 13, 2020

The "Child Certificate" program, launched in Armenia in 2011, made hospitalization for children less than seven years free in order to improve access to hospitalization, reduce out-of-pocket expenses ...

Overview of The 2019 Novel Coronavirus (2019-nCoV): The Pathogen of Severe Specific Contagious Pneumonia (SSCP).

Feb 13, 2020

In late December 2019 a previous unidentified coronavirus, currently named as the 2019 novel coronavirus (2019-nCoV), emerged from Wuhan, China and resulted in a formidable outbreak in many cities in ...

Risk factors for the development of aspiration pneumonia in elderly patients with femoral neck and trochanteric fractures: A retrospective study of a patient cohort.

Feb 13, 2020

Aspiration pneumonia (AP) has been recognized as one of the most common postoperative complications after hip surgery in elderly. The objective of the present study was to evaluate risk for postoperat...

Higher Long-Term Mortality with Carotid Artery Stenting in Asymptomatic Male Compared to Female Patients in the Southeastern Vascular Study Group.

Feb 13, 2020

To review the sex differences among symptomatic and asymptomatic patients treated with carotid endarterectomy (CEA) and carotid stenting (CAS) in the Southeastern Vascular Study Group (SEVSG), a regio...

Differences in presentation and clinical outcomes between left or right bundle branch block and ST segment elevation in patients with acute myocardial infarction.

Feb 13, 2020

In patients with acute myocardial infarction, the presence of a left bundle branch block or right bundle branch block may be associated with worse prognosis compared to isolated ST segment elevation. ...

Identifying critically important cardiovascular outcomes for trials in hemodialysis: an international survey with patients, caregivers and health professionals.

Feb 13, 2020

Cardiovascular disease (CVD) is a major contributor to morbidity and mortality in people on hemodialysis (HD). Cardiovascular outcomes are reported infrequently and inconsistently across trials in HD....

Efficiency, Safety, and Quality of Life After Transcatheter Aortic Valve Implantation Performed With Moderate Sedation Versus General Anesthesia.

Feb 13, 2020

There is growing interest in "minimalist" transcatheter aortic valve implantation (M-TAVI), performed with conscious sedation instead of general anesthesia (GA-TAVI). We assessed the impact of M-TAVI ...

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