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Critical Care General

Quantitative analysis of revascularization in ischemic moyamoya disease via whole-brain computed tomography perfusion: A retrospective single-center study.

Feb 13, 2020

Ischemic moyamoya disease (MMD) can be treated with the revascularization of superficial temporal artery to middle cerebral artery (STA-MCA) bypass combined with encephalo-duro-arterio-myo-synangiosis...

Potential Therapeutic Application of Zinc Oxide Nanoflowers in Cerebral Ischemia Rat Model Through Neuritogenic and Neuroprotective Properties.

Feb 13, 2020

Neuritogenesis, a complex process of sprouting of neurites, plays vital role in structural and functional restoration of cerebral ischemia injured neuronal tissue. Practically, there is no effective l...

Sequential changes of NLRP3 inflammasome activation in sepsis and its relationship with death.

Feb 13, 2020

Inflammasomes are recognized as key components of the innate immune response in sepsis. We aimed to describe the transcriptional expression of nucleotide-binding domain, leucine-rich repeat-containing...

Value of Serum Uncoupling Protein-2 Level for Patients with Sepsis

Feb 13, 2020

To investigate the potential utility of serum uncoupling protein-2 (UCP2) level as a biomarker in septic patients.Critically ill patients with diagnoses of sepsis - sepsis non-shock group (n = 20)...

Long-term mortality and outcome in hospital survivors of septic shock, sepsis, and severe infections: The importance of aftercare.

Feb 13, 2020

Patients with severe infections and especially sepsis have a high in-hospital mortality, but even hospital survivors face long-term sequelae, decreased health-related quality of life, and high risk of...

Free hospitalization for acute respiratory infections in children: what effect and how much does it cost for Armenia?

Feb 13, 2020

The "Child Certificate" program, launched in Armenia in 2011, made hospitalization for children less than seven years free in order to improve access to hospitalization, reduce out-of-pocket expenses ...

Overview of The 2019 Novel Coronavirus (2019-nCoV): The Pathogen of Severe Specific Contagious Pneumonia (SSCP).

Feb 13, 2020

In late December 2019 a previous unidentified coronavirus, currently named as the 2019 novel coronavirus (2019-nCoV), emerged from Wuhan, China and resulted in a formidable outbreak in many cities in ...

Risk factors for the development of aspiration pneumonia in elderly patients with femoral neck and trochanteric fractures: A retrospective study of a patient cohort.

Feb 13, 2020

Aspiration pneumonia (AP) has been recognized as one of the most common postoperative complications after hip surgery in elderly. The objective of the present study was to evaluate risk for postoperat...

Higher Long-Term Mortality with Carotid Artery Stenting in Asymptomatic Male Compared to Female Patients in the Southeastern Vascular Study Group.

Feb 13, 2020

To review the sex differences among symptomatic and asymptomatic patients treated with carotid endarterectomy (CEA) and carotid stenting (CAS) in the Southeastern Vascular Study Group (SEVSG), a regio...

Differences in presentation and clinical outcomes between left or right bundle branch block and ST segment elevation in patients with acute myocardial infarction.

Feb 13, 2020

In patients with acute myocardial infarction, the presence of a left bundle branch block or right bundle branch block may be associated with worse prognosis compared to isolated ST segment elevation. ...

Identifying critically important cardiovascular outcomes for trials in hemodialysis: an international survey with patients, caregivers and health professionals.

Feb 13, 2020

Cardiovascular disease (CVD) is a major contributor to morbidity and mortality in people on hemodialysis (HD). Cardiovascular outcomes are reported infrequently and inconsistently across trials in HD....

Efficiency, Safety, and Quality of Life After Transcatheter Aortic Valve Implantation Performed With Moderate Sedation Versus General Anesthesia.

Feb 13, 2020

There is growing interest in "minimalist" transcatheter aortic valve implantation (M-TAVI), performed with conscious sedation instead of general anesthesia (GA-TAVI). We assessed the impact of M-TAVI ...

Biomarkers of Inflammation and Etiology of Sepsis

Feb 13, 2020

Sepsis is characterized as a life-threatening organ dysfunction syndrome that is caused by a dysregulated host response to infection. The main etiological causes of sepsis are bacterial, fungal, and v...

Association of Surgical Jacket and Bouffant Use With Surgical Site Infection Risk

Feb 13, 2020

Surgical site infections (SSIs) are associated with increased morbidity and mortality. Various measures have been enacted decrease the occurrence of SSIs involving the regulation of the attire worn by...

Lipid Use in Hospitalized Adults Requiring Parenteral Nutrition

Feb 13, 2020

In hospitalized patients, lipid emulsions are an integral part of balanced parenteral nutrition. Traditionally, a single lipid source, soybean oil, has been given to patients and was usually regarded ...

Elevated procalcitonin levels in patients with acetaminophen intoxication: two case reports: A CARE-compliant article.

Feb 13, 2020

Procalcitonin (PCT) is used as a biomarker for identifying the occurrence of sepsis. Previous studies have reported high levels of PCT with acetaminophen intoxication without evidence of infection. He...

The Impact of Hyperoxia in Critically Ill Patient

Feb 13, 2020

Oxygen has long been considered a vital and potentially life-saving component of emergency care. Given this, there is widespread and liberal use of supplemental oxygen in hospitals across the United S...

Platelet CLEC-2 regulates neuroinflammation and restores blood brain barrier integrity in a mouse model of traumatic brain injury.

Feb 13, 2020

Neuroinflammation accompanied by microglial activation triggers multiple cell death after traumatic brain injury (TBI). The secondary injury caused by inflammation may persist for a long time. Recentl...

Use of high-sensitivity digital ELISA improves the diagnostic performance of circulating brain-specific proteins for detection of traumatic brain injury during triage.

Feb 13, 2020

: Historically, limited sensitivity associated with traditional immunoassay methods has prevented the use of brain-specific proteins as blood biomarkers of traumatic brain injury (TBI) during triage, ...

Initial Kinetic Characterization of Sterile Alpha and Toll/Interleukin Receptor Motif-Containing Protein 1.

Feb 13, 2020

Sterile alpha and toll/interleukin receptor (TIR) motif-containing protein 1 (SARM1) plays a pivotal role in triggering the neurodegenerative processes that underlie peripheral neuropathies, traumatic...

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