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Critical Care General

Immunocal® limits gliosis in mouse models of repetitive mild-moderate traumatic brain injury.

Mar 27, 2023

Successive traumatic brain injuries (TBIs) exacerbate neuroinflammation and oxidative stress. No therapeutics exist for populations at high risk of repetitive mild TBIs (rmTBIs). We explored the preve...

Inhibiting degradation of 2-arachidonoylglycerol as a therapeutic strategy for neurodegenerative diseases.

Mar 27, 2023

Endocannabinoids are endogenous lipid signaling mediators that participate in a variety of physiological and pathological processes. 2-Arachidonoylglycerol (2-AG) is the most abundant endocannabinoid ...

Gender-specific prevalence and trend of heart failure in China from 1990 to 2019.

Mar 27, 2023

Heart failure (HF) is one of the leading causes of the global burden of disability and mortality. However, the comprehensive epidemic status of HF in China is unclear. Notably, the gender-specific sur...

The Effect of Social Determinants of Health on the Progression of Pressure Injury

Mar 24, 2023

The following is a summary of "Impact of Social Determinants of Health on Pressure Injury Progression: A Retrospective Chart and Scoping Review," published in the February 2023 issue of Critical Care ...

Lessons Learned from the COVID-19 Pandemic: Responding to the Anticipated Ventilator Shortage

Mar 22, 2023

The following is the summary of “COVID-19 Lessons Learned: Response to the Anticipated Ventilator Shortage” published in the January 2023 issue of Respiratory Care by Branson, et al. Predic...

Global Vs. National Asthma Management Guidelines: A Comparative Analysis

Mar 21, 2023

The following is the summary of “Comparison of National and Global Asthma Management Guiding Documents” published in the January 2023 issue of Respiratory Care by Baker, et al. Asthma conti...

Epinephrine Administration Routes' Effects on Acute MI Patients with Cardiac Arrest in the Catheterization Lab

Mar 20, 2023

The following is the summary of “A prospective observational study on impact of epinephrine administration route on acute myocardial infarction patients with cardiac arrest in the catheterization la...

Preparation, characterization and safety evaluation of Ligusticum chuanxiong essential oils liposomes for treatment of cerebral ischemia-reperfusion injury.

Mar 20, 2023

The essential oils of Ligusticum chuanxiong Hort. (CXEO) are considered to be important parts of the pharmacological action of Ligusticum chuanxiong Hort. CXEO have a wide range of applications in var...

Association of Conventional Ultrafiltration on Postoperative Pulmonary Complications.

Mar 20, 2023

Postoperative pulmonary complications increase mortality following cardiac surgery. Conventional ultrafiltration may reduce pulmonary complications by removing mediators of bypass-induced inflammation...

Using LASSO regression to estimate the population-level impact of pneumococcal conjugate vaccines.

Mar 20, 2023

The pneumococcal conjugate vaccines (PCVs) protect against diseases caused by Streptococcus pneumoniae, such as meningitis, bacteremia, and pneumonia. It is challenging to estimate their population-le...

Spontaneous rupture of an infected pseudocyst of the pancreas: A case report.

Mar 20, 2023

A pancreatic pseudocyst is a known complication of acute and chronic pancreatitis. A pseudocyst rupture into the abdomen causes peritonitis, which can be fatal if surgical treatment is delayed. Here i...

Treatment of Septic Tenosynovitis and Osteoarthritis in an American White Pekin () with Repeated Intravenous Regional Limb Perfusion and Antibiotic-Impregnated Calcium Sulfate Beads.

Mar 20, 2023

A 2-year-old female American white pekin () was assessed for a 2-month history of chronic lameness and swelling involving the left leg. Radiographic images of the left leg showed soft tissue swelling ...

Inflammaging, cellular senescence, and cognitive aging after traumatic brain injury.

Mar 20, 2023

Traumatic brain injury (TBI) is associated with mortality and morbidity worldwide. Accumulating pre-clinical and clinical data suggests TBI is the leading extrinsic cause of progressive neurodegenerat...

Comparing the Efficacy of Patient Bed Positioning Devices in Participants with Able-bodied & Tetraplegia Using Pressure Mapping

Mar 17, 2023

The following is a summary of "Using Pressure Mapping to Compare Efficacy of Patient Bed Positioning Devices in Participants Who Are Able-Bodied and Those with Tetraplegia," published in the February ...

Development and Validation of a Score-Based Prediction Model for SVDD in Critically Ill Patients

Mar 17, 2023

The following is the summary of “Score-based prediction model for severe vitamin D deficiency in patients with critical illness: development and validation” published in the December 2022 issue of...

Top 11 Priorities to Enhance Trauma Outcomes from a System to a Patient-Level Perspective

Mar 16, 2023

The following is the summary of “Perspective: the top 11 priorities to improve trauma outcomes, from system to patient level” published in the December 2022 issue of Critical care by Reade, et al....

Association Between Mechanical Ventilation Variables and PAP in ARDS Patients

Mar 15, 2023

The following is the summary of “Mechanical ventilation variables associated with high pulmonary artery pressures in ARDS patients: a post hoc analysis” published in the December 2022 issue of Cri...

Characteristics and Outcomes of Invasive Mechanical Ventilation Weaning in Patients with COVID-19

Mar 14, 2023

The following is the summary of “Epidemiology of Weaning From Invasive Mechanical Ventilation in Subjects With COVID-19” published in the January 2023 issue of Respiratory Care by Dorado, et al. ...

Comparison of Non-Interventional FU and Fluid Bolus in Response to Oliguria in hemodynamically stable patients

Mar 14, 2023

The following is the summary of “Non-interventional follow-up versus fluid bolus in RESPONSE to oliguria in hemodynamically stable critically ill patients: a randomized controlled pilot trial” pub...

Impact of High-Flow Oxygen Vs. T-Piece Ventilation Strategies on Weaning Failure in Mechanically Ventilated Patients undergoing SBT

Mar 13, 2023

The following is the summary of “Effect of high-flow oxygen versus T-piece ventilation strategies during spontaneous breathing trials on weaning failure among patients receiving mechanical ventilati...

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