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Critical Care General

Monitoring of Medullary Oxygenation in Critically Ill Patients Using Continuous Bladder Urinary Oxygen Tension

Mar 30, 2023

The following is the summary of “Continuous bladder urinary oxygen tension as a new tool to monitor medullary oxygenation in the critically ill” published in the December 2022 issue of Critical ca...

Ten Guidelines to Optimize Ventilator Targets and Settings in Post-CA Patients

Mar 29, 2023

The following is the summary of “Ten rules for optimizing ventilatory settings and targets in post-cardiac arrest patients” published in the December 2022 issue of Critical care by Battaglini, et ...

Heat Stroke-induced Liver Injury: Pathogenesis & Therapeutic Strategies

Mar 28, 2023

The following is the summary of “Pathogenesis and therapeutic strategies of heat stroke-induced liver injury” published in the December 2022 issue of Critical care by Wang, et al. Heat stro...

Biotrauma and Ultra-lung-protective Ventilation in Patients with Severe ARDS Receiving vv-ECMO

Mar 27, 2023

The following is the summary of “Ultra-lung-protective ventilation and biotrauma in severe ARDS patients on veno-venous extracorporeal membrane oxygenation: a randomized controlled study” publishe...

Anti-CHAC1 exosomes for nose-to-brain delivery of miR-760-3p in cerebral ischemia/reperfusion injury mice inhibiting neuron ferroptosis.

Mar 27, 2023

Ferroptosis plays a critical role in ischemic stroke, and anti-ferroptosis strategies were regarded as potentially effective measures. Based on ferroptosis-related mechanisms, this study aims to desig...

Characteristics of acid-sensing ion channel currents in male rat muscle dorsal root ganglion neurons following ischemia/reperfusion.

Mar 27, 2023

Peripheral artery diseases (PAD) increases muscle afferent nerve-activated reflex sympathetic nervous and blood pressure responses during exercise (termed as exercise pressor reflex). However, the pre...

Gut microbiota disruption during sepsis and the influence of innate metabolites on sepsis prognosis.

Mar 27, 2023

Sepsis causes high mortality in intensive care units. Although there have been many studies on the gut microbiota in patients with sepsis, the impact of sepsis on the gut microbiota has not been direc...

Impact of corticosteroids on the duration of ventilatory support during severe acute exacerbations of chronic obstructive pulmonary disease in patients in the intensive care unit: a study protocol for a multicentre, randomized, placebo-controlled, double-blind trial.

Mar 27, 2023

Patients who are admitted to the intensive care unit (ICU) for severe acute exacerbations of chronic obstructive pulmonary disease (COPD) have poor outcomes. Although international clinical practice g...

Treatment of severe acute necrotizing encephalopathy of childhood with interleukin-6 receptor blockade in the first 24 h as add-on immunotherapy shows favorable long-term outcome at 2 years.

Mar 27, 2023

Acute necrotizing encephalopathy (ANE) of childhood is a rare and devastating infection-associated acute encephalopathy. While there are no consensus treatments for ANE, recent case reports suggest a ...

Immunocal® limits gliosis in mouse models of repetitive mild-moderate traumatic brain injury.

Mar 27, 2023

Successive traumatic brain injuries (TBIs) exacerbate neuroinflammation and oxidative stress. No therapeutics exist for populations at high risk of repetitive mild TBIs (rmTBIs). We explored the preve...

Inhibiting degradation of 2-arachidonoylglycerol as a therapeutic strategy for neurodegenerative diseases.

Mar 27, 2023

Endocannabinoids are endogenous lipid signaling mediators that participate in a variety of physiological and pathological processes. 2-Arachidonoylglycerol (2-AG) is the most abundant endocannabinoid ...

Gender-specific prevalence and trend of heart failure in China from 1990 to 2019.

Mar 27, 2023

Heart failure (HF) is one of the leading causes of the global burden of disability and mortality. However, the comprehensive epidemic status of HF in China is unclear. Notably, the gender-specific sur...

The Effect of Social Determinants of Health on the Progression of Pressure Injury

Mar 24, 2023

The following is a summary of "Impact of Social Determinants of Health on Pressure Injury Progression: A Retrospective Chart and Scoping Review," published in the February 2023 issue of Critical Care ...

Lessons Learned from the COVID-19 Pandemic: Responding to the Anticipated Ventilator Shortage

Mar 22, 2023

The following is the summary of “COVID-19 Lessons Learned: Response to the Anticipated Ventilator Shortage” published in the January 2023 issue of Respiratory Care by Branson, et al. Predic...

Global Vs. National Asthma Management Guidelines: A Comparative Analysis

Mar 21, 2023

The following is the summary of “Comparison of National and Global Asthma Management Guiding Documents” published in the January 2023 issue of Respiratory Care by Baker, et al. Asthma conti...

Epinephrine Administration Routes' Effects on Acute MI Patients with Cardiac Arrest in the Catheterization Lab

Mar 20, 2023

The following is the summary of “A prospective observational study on impact of epinephrine administration route on acute myocardial infarction patients with cardiac arrest in the catheterization la...

Preparation, characterization and safety evaluation of Ligusticum chuanxiong essential oils liposomes for treatment of cerebral ischemia-reperfusion injury.

Mar 20, 2023

The essential oils of Ligusticum chuanxiong Hort. (CXEO) are considered to be important parts of the pharmacological action of Ligusticum chuanxiong Hort. CXEO have a wide range of applications in var...

Association of Conventional Ultrafiltration on Postoperative Pulmonary Complications.

Mar 20, 2023

Postoperative pulmonary complications increase mortality following cardiac surgery. Conventional ultrafiltration may reduce pulmonary complications by removing mediators of bypass-induced inflammation...

Using LASSO regression to estimate the population-level impact of pneumococcal conjugate vaccines.

Mar 20, 2023

The pneumococcal conjugate vaccines (PCVs) protect against diseases caused by Streptococcus pneumoniae, such as meningitis, bacteremia, and pneumonia. It is challenging to estimate their population-le...

Spontaneous rupture of an infected pseudocyst of the pancreas: A case report.

Mar 20, 2023

A pancreatic pseudocyst is a known complication of acute and chronic pancreatitis. A pseudocyst rupture into the abdomen causes peritonitis, which can be fatal if surgical treatment is delayed. Here i...

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