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Critical Care General

Treatment of Septic Tenosynovitis and Osteoarthritis in an American White Pekin () with Repeated Intravenous Regional Limb Perfusion and Antibiotic-Impregnated Calcium Sulfate Beads.

Mar 20, 2023

A 2-year-old female American white pekin () was assessed for a 2-month history of chronic lameness and swelling involving the left leg. Radiographic images of the left leg showed soft tissue swelling ...

Inflammaging, cellular senescence, and cognitive aging after traumatic brain injury.

Mar 20, 2023

Traumatic brain injury (TBI) is associated with mortality and morbidity worldwide. Accumulating pre-clinical and clinical data suggests TBI is the leading extrinsic cause of progressive neurodegenerat...

Comparing the Efficacy of Patient Bed Positioning Devices in Participants with Able-bodied & Tetraplegia Using Pressure Mapping

Mar 17, 2023

The following is a summary of "Using Pressure Mapping to Compare Efficacy of Patient Bed Positioning Devices in Participants Who Are Able-Bodied and Those with Tetraplegia," published in the February ...

Development and Validation of a Score-Based Prediction Model for SVDD in Critically Ill Patients

Mar 17, 2023

The following is the summary of “Score-based prediction model for severe vitamin D deficiency in patients with critical illness: development and validation” published in the December 2022 issue of...

Top 11 Priorities to Enhance Trauma Outcomes from a System to a Patient-Level Perspective

Mar 16, 2023

The following is the summary of “Perspective: the top 11 priorities to improve trauma outcomes, from system to patient level” published in the December 2022 issue of Critical care by Reade, et al....

Association Between Mechanical Ventilation Variables and PAP in ARDS Patients

Mar 15, 2023

The following is the summary of “Mechanical ventilation variables associated with high pulmonary artery pressures in ARDS patients: a post hoc analysis” published in the December 2022 issue of Cri...

Characteristics and Outcomes of Invasive Mechanical Ventilation Weaning in Patients with COVID-19

Mar 14, 2023

The following is the summary of “Epidemiology of Weaning From Invasive Mechanical Ventilation in Subjects With COVID-19” published in the January 2023 issue of Respiratory Care by Dorado, et al. ...

Comparison of Non-Interventional FU and Fluid Bolus in Response to Oliguria in hemodynamically stable patients

Mar 14, 2023

The following is the summary of “Non-interventional follow-up versus fluid bolus in RESPONSE to oliguria in hemodynamically stable critically ill patients: a randomized controlled pilot trial” pub...

Impact of High-Flow Oxygen Vs. T-Piece Ventilation Strategies on Weaning Failure in Mechanically Ventilated Patients undergoing SBT

Mar 13, 2023

The following is the summary of “Effect of high-flow oxygen versus T-piece ventilation strategies during spontaneous breathing trials on weaning failure among patients receiving mechanical ventilati...

Effects of hyperoxemia in patients with sepsis - A post-hoc analysis of a multicentre randomized clinical trial.

Mar 13, 2023

Administration of supplemental oxygen is a life-saving treatment in critically ill patients. Still, optimal dosing remains unclear during sepsis. The aim of this post-hoc analysis was to assess the as...

Knockdown of adenosine A2A receptors in hippocampal neurons prevents post-TBI fear memory retrieval.

Mar 13, 2023

The formation of fear memory is crucial in emotional disorders such as PTSD and anxiety. Traumatic brain injury (TBI) can cause emotional disorders with dysregulated fear memory formation; however, th...

Beyond uncal herniation: An updated diagnostic reappraisal of ipsilateral hemiparesis and the Kernohan-Woltman notch phenomenon.

Mar 13, 2023

This works comprehensively analyses a modern cohort of patients with ipsilateral hemiparesis (IH) and discusses the pathophysiological theories elaborated to explain this paradoxical neurological sign...

Diagnostic Pathways to Wild-Type Transthyretin Amyloid Cardiomyopathy: a Multicenter Network Study.

Mar 13, 2023

Epidemiology of wild-type transthyretin cardiac amyloidosis (ATTRwt-CA) remains poorly defined. A better characterization of pathways leading to ATTRwt-CA diagnosis is of key importance, and potential...

Critically ill severe hypothyroidism: a retrospective multicenter cohort study.

Mar 13, 2023

Severe hypothyroidism (SH) is a rare but life-threatening endocrine emergency. Only a few data are available on its management and outcomes of the most severe forms requiring ICU admission. We aimed t...

Limitations of Breath-by-Breath P0.1 Measurement on Quasi-occlusion through Hamilton C6: Underestimation of Inspiratory Effort and Respiratory Drive

Mar 10, 2023

The following is the summary of “Breath-by-breath P0.1 measured on quasi-occlusion via Hamilton C6 may result in underestimation of respiratory drive and inspiratory effort” published in the Decem...

Assessment and Rate of Muscle Wasting During Illness

Mar 09, 2023

The following is the summary of “Rate and assessment of muscle wasting during critical illness: a systematic review and meta-analysis” published in the January 2023 issue of Critical care by Fazzi...

GCSE Adjuvant Treatment in Valproic Acid During Clinical Trial

Mar 07, 2023

The following is the summary of “Valproic acid as adjuvant treatment for convulsive status epilepticus: a randomised clinical trial” published in the January 2023 issue of Critical care by Sharsha...

Baricitinib's Effectiveness and Safety in Treating Hospitalized Adults with Severe COVID-19

Mar 06, 2023

The following is the summary of “Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID-19 (Bari-SolidAct): a randomized, double-blind, placebo-controlled phase 3 tr...

Subcutaneous implantable cardioverter-defibrillator therapy in Poland: Results of the Polish S-ICD Registry.

Mar 06, 2023

The use of a subcutaneous implantable cardioverter-defibrillator (S-ICD) has been expanding in Poland since 2014. The Polish Registry of S-ICD Implantations was held by the Heart Rhythm Section of the...

Intensification of treatment with vinca alkaloid does not improve outcomes in pediatric patients with Langerhans cell histiocytosis: results from the JPLSG LCH-12 study.

Mar 06, 2023

Chemotherapy with cytarabine, vincristine (VCR), and prednisolone has achieved low mortality rates in pediatric patients with Langerhans cell histiocytosis (LCH). However, relapse rates remain high, m...

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