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Critical Care General

Baricitinib's Effectiveness and Safety in Treating Hospitalized Adults with Severe COVID-19

Mar 06, 2023

The following is the summary of “Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID-19 (Bari-SolidAct): a randomized, double-blind, placebo-controlled phase 3 tr...

Subcutaneous implantable cardioverter-defibrillator therapy in Poland: Results of the Polish S-ICD Registry.

Mar 06, 2023

The use of a subcutaneous implantable cardioverter-defibrillator (S-ICD) has been expanding in Poland since 2014. The Polish Registry of S-ICD Implantations was held by the Heart Rhythm Section of the...

Intensification of treatment with vinca alkaloid does not improve outcomes in pediatric patients with Langerhans cell histiocytosis: results from the JPLSG LCH-12 study.

Mar 06, 2023

Chemotherapy with cytarabine, vincristine (VCR), and prednisolone has achieved low mortality rates in pediatric patients with Langerhans cell histiocytosis (LCH). However, relapse rates remain high, m...

Identification and quantification of nine compounds in fangwen jiuwei decoction by liquid chromatography-mass spectrometry.

Mar 06, 2023

Fangwen Jiuwei Decoction is a traditional Chinese medicine preparation for the treatment of pneumonia developed by Shenzhen Bao'an Chinese Medicine Hospital, which shows remarkable clinical responses....

Extremely high unbound flucloxacillin concentrations in a patient with acute septic renal failure during continuous venovenous hemofiltration: Therapeutic drug monitoring to optimize treatment.

Mar 06, 2023

A 75-year-old female orthopedic patient with spondylodiscitis was admitted to the intensive care unit, where she developed severe acute renal injury (AKI) due to a bloodstream infection. Continuous v...

Association between gut microbiota and delirium in acutely ill older adults.

Mar 06, 2023

Our aim was to investigate the association between gut microbiota and delirium occurrence in acutely ill older adults. We included 133 participants 65+ years consecutively admitted to the emergency de...

Trends in Traumatic Brain Injury Among U.S. Service Members Deployed in Iraq and Afghanistan, 2002-2016.

Mar 06, 2023

Traumatic brain injury (TBI) is a major health issue for service members deployed and is more common in recent conflicts; however, a thorough understanding of risk factors and trends is not well descr...

Colorectal Cancer-Related Enterostomy Patients' Psychological Distress

Mar 03, 2023

The following is a summary of "Predictors of Psychological Distress among Patients with Colorectal Cancer-Related Enterostomy: A Cross-sectional Study," published in the February 2023 issue of Critica...

Clinical Outcomes of COPD During Continuous Monitoring of Pulse Oximetry

Mar 02, 2023

The following is the summary of “Continuous Monitoring of Pulse Oximetry During the 6-Minute Walk Test Improves Clinical Outcomes Prediction in COPD” published in the January 2023 issue of Respira...

Corticosteroids' Effectiveness and Safety in Cardiac Arrest

Mar 01, 2023

The following is the summary of “Efficacy and safety of corticosteroids in cardiac arrest: a systematic review, meta-analysis and trial sequential analysis of randomized control trials” published ...

Bundle of ‘THE MANTLE’ to Minimize Cerebral Hypoxia in Severe Traumatic Brain Injury

Feb 28, 2023

The following is the summary of “THE MANTLE” bundle for minimizing cerebral hypoxia in severe traumatic brain injury” published in the January 2023 issue of Critical care by Godoy, et al. ...

Comparing Prolonged Sedation With IV Sedation and Sevoflurane in Critically Ill Patients

Feb 27, 2023

The following is the summary of “Prolonged sedation with sevoflurane in comparison to intravenous sedation in critically ill patients – A randomized controlled trial” published in the January 20...

The Effect of Metformin on Vitamin B12 Deficiency and Stroke.

Feb 27, 2023

Type 2 diabetes mellitus (T2DM) is a known risk factor for cardiovascular disease and stroke. Metformin is an old, relatively safe, first line therapy for T2DM; however, it has been associated with st...

A 37-Year-Old Man with Familial Hereditary Hemorrhagic Telangiectasia and Pulmonary Arteriovenous Malformations Presenting with Seizures and a Diagnosis of Brain Abscesses.

Feb 27, 2023

BACKGROUND Hereditary hemorrhagic telangiectasia (HHT) is a rare autosomal dominant genetic disease associated with arteriovenous malformations involving diverse organs. Neurological complications fro...

Endoscopic ultrasound-guided biliary drainage for distal malignant biliary obstruction: a prospective 3-year multicenter Egyptian study.

Feb 27, 2023

Malignant biliary obstruction (MBO) is often diagnosed at late stages with mostly unresectable lesions. Recently, EUS-guided biliary drainage (EUS-BD) has gained wide acceptance and appears to be a fe...

Remote Patient Monitoring for Management of Diabetes in Pregnancy is Associated with Improved Maternal and Neonatal Outcomes.

Feb 27, 2023

Diabetes is a common medical complication of pregnancy and its treatment is complex. Recent years have seen an increase in the application of mobile health tools and advanced technologies, such as rem...

Comorbidities in autism spectrum disorder and their etiologies.

Feb 27, 2023

Individuals with autism spectrum disorder (ASD), in addition to the core features of the disease, experience a higher burden of co-occurring medical conditions. This study sought to describe the frequ...

Sex-specific differences in resting-state functional brain activity in pediatric concussion.

Feb 27, 2023

Pediatric concussion has a rising incidence and can lead to long-term symptoms in nearly 30% of children. Resting state functional magnetic resonance imaging (rs-fMRI) disturbances are a common pathol...

Heart failure treatment in patients with and without obesity with an ejection fraction below 50.

Feb 27, 2023

The aim of this study was to assess heart failure (HF) treatment in patients with and without obesity in a large contemporary real-world Western European cohort.Patients with a left ventricular ejecti...

Associated Harms and High-Risk Phenotypes in Delayed Time-to-Antibiotics Patients with Onset Sepsis

Feb 23, 2023

The following is the summary of “Identifying high-risk phenotypes and associated harms of delayed time-to-antibiotics in patients with ICU onset sepsis: A retrospective cohort study” published in ...

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