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Critical Care General

Biologic Controls and Cardiopulmonary Exercise Testing Variability

Feb 14, 2023

The following is the summary of  “Variability in Cardiopulmonary Exercise Testing Biologic Controls” published in the January 2023 issue of Respiratory Care January by DeCato, et al. Cardi...

Effect of Accidental Air Leaks on the Efficiency of Automatic PAP Devices in Simulated Sleep Apnea Events

Feb 13, 2023

The following is the summary of  “Impact of Unintentional Air Leaks on Automatic Positive Airway Pressure Device Performance in Simulated Sleep Apnea Events” published in the January 2023 issue o...

Epigenetic mechanisms of Immune remodeling in sepsis: targeting histone modification.

Feb 13, 2023

Sepsis is a life-threatening disorder disease defined as infection-induced dysregulated immune responses and multiple organ dysfunction. The imbalance between hyperinflammation and immunosuppression i...

Plasma calprotectin as an indicator of need of transfer to intensive care in patients with suspected sepsis at the emergency department.

Feb 13, 2023

Deciding whether to transfer patients with sepsis from the emergency department (ED) to intensive care units (ICUs) is challenging. We hypothesised that the new biomarker plasma calprotectin (p-calpro...

HLA-haploidentical hematopoietic stem cells transplantation with regulatory and conventional T-cell adoptive immunotherapy in pediatric patients with very high-risk acute leukemia.

Feb 13, 2023

Allogeneic hematopoietic stem cell transplantation (HSCT) is still needed for many children with very high-risk acute leukemia. An HLA-haploidentical family donor is a suitable option for those withou...

Anomalous aortic origin of the left coronary artery.

Feb 13, 2023

We present an unusual case of an anomalous left coronary artery arising from the contralateral sinus of Valsalva: a 63-year-old male patient who consulted to our emergency department with 1-week histo...

[Congenital heart diseases in patients above the age of 60 years.].

Feb 13, 2023

Development in paediatric and interventional cardiology and cardiac surgery resulted in an increase in the number and average age of adult congenital heart disease patients. Comorbidities may appear w...

Evaluating a Potential National Board for Respiratory Care Credential for Pulmonary Disease Educators.

Feb 13, 2023

The National Board for Respiratory Care (NBRC) credentials general respiratory therapists and therapists specializing in pulmonary function testing, neonatal/pediatrics, sleep, and adult critical care...

Management of Intracerebral Haemorrhage in an Emergency

Feb 10, 2023

The following is the summary of “Emergency management of intracerebral hemorrhage” published in the April 2023 issue of Critical Care by Mazzoleni, et al. An acute intracerebral hemorrhage ...

Sleep-Related Respiratory Events in NIV Technologies

Feb 09, 2023

The following is the summary of “Noninvasive Ventilation Automated Technologies: A Bench Evaluation of Device Responses to Sleep-Related Respiratory Events” published in the January 2023 issue of ...

SARS-CoV-2 Characterization in Aerosols Released During NRS in COVID-19 Patients

Feb 08, 2023

The following is the summary of “Characterization of SARS-CoV-2 Aerosols Dispersed During Noninvasive Respiratory Support of Patients With COVID-19” published in the January 2023 issue of Respirat...

Environmental Contamination During COVID-19 Noninvasive Ventilation

Feb 07, 2023

The following is the summary of “Environmental Contamination by SARS-CoV-2 During Noninvasive Ventilation in COVID-19” published in the January 2023 issue of Respiratory Care by Dell’Olio, et al...

Contrast-induced Nephropathy in Kidney Transplant Recipients: A Single-center Experience.

Feb 06, 2023

Data regarding contrast-induced nephropathy (CIN) in kidney transplant (KT) recipients are scarce despite the distinct risk factors such as the use of immunosuppressive agents, sympathetic denervation...

Risk factors of post-traumatic stress disorder after hospitalization in a pediatric intensive care unit: a systematic literature review.

Feb 06, 2023

The number of studies on post-traumatic stress disorder after hospitalization in a pediatric intensive care unit raised since 2004. The objective of this systematic review was to summarize and critica...

Determination of the synergistic anti-influenza effect of Huangqin Su tablet and Oseltamivir and investigation of mechanism of the tablet based on gut microbiota and network pharmacology.

Feb 06, 2023

Huangqin Su (HQS) tablet is mainly composed of baicalein which has been evaluated for its ability to inhibit influenza. The present study aimed to investigate the effect of HQS and oseltamivir phospha...

Pulse oximetry: why oxygen saturation is still not a part of standard pediatric guidelines in low-and-middle-income countries (LMICs).

Feb 06, 2023

With the high frequency of acute respiratory infections in children worldwide, particularly so in low-resource countries, the development of effective diagnostic support is crucial. While pulse oximet...

Forsythiaside A ameliorates sepsis-induced acute kidney injury via anti-inflammation and antiapoptotic effects by regulating endoplasmic reticulum stress.

Feb 06, 2023

Sepsis is a systemic inflammatory response syndrome caused by an infection in the body, and accompanying acute kidney injury (AKI) is a common complication of sepsis. It is associated with increased m...

Blood glutamate scavenging as a novel glutamate-based therapeutic approach for post-traumatic brain injury anxiety and social impairment.

Feb 06, 2023

Traumatic brain injury (TBI) is a serious condition that is associated with an increased risk of severe, long-term psychiatric consequences. Drugs that target the glutamatergic system have proven succ...

Astrocyte-derived Exosomal lncRNA 4933431K23Rik Modulate Microglial Phenotype and Improve Post-traumatic Recovery via SMAD7 Regulation.

Feb 06, 2023

Astrocyte-microglial interaction plays a crucial role in brain injury-associated neuroinflammation. Our previous data illustrated that astrocytes secrete microRNA, leading to anti-inflammatory effects...

Epinephrine in Out-of-Hospital Cardiac Arrest - A Network Meta-Analysis and Subgroup Analyses of Shockable and Non-Shockable Rhythms.

Feb 06, 2023

Epinephrine is the most commonly used drug in out-of-hospital cardiac arrest (OHCA) resuscitation, but evidence supporting its efficacy is mixed.What is the comparative efficacy and safety of standard...

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