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Critical Care General

Activation of cannabinoid-2 receptor protects against Pseudomonas aeruginosa induced acute lung injury and inflammation.

Dec 05, 2022

Bacterial pneumonia is a major risk factor for acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Pseudomonas aeruginosa (PA), an opportunistic pathogen with an increasing resista...

Acinetobacter baumannii reinforces the pathogenesis by promoting IL-17 production in a mouse pneumonia model.

Dec 05, 2022

Interleukin-17 (IL-17) is involved in host defense against bacterial infection. Little is known about the role of IL-17 in A. baumannii-infected pneumonia. Our objective was to investigate the role o...

Vaginal Cleansing Before Unscheduled Cesarean Delivery to Reduce Infection: A Randomized Clinical Trial.

Dec 05, 2022

Cesarean delivery (CD) is the most performed major surgery in women and surgical site infections following CD are a significant source of postoperative morbidity. It is unclear whether vaginal cleansi...

TREM2 activation alleviates neural damage via Akt/CREB/BDNF signalling after traumatic brain injury in mice.

Dec 05, 2022

Neuroinflammation is one of the most important processes in secondary injury after traumatic brain injury (TBI). Triggering receptor expressed on myeloid cells 2 (TREM2) has been proven to exert neuro...

TREM2 activation alleviates neural damage via Akt/CREB/BDNF signalling after traumatic brain injury in mice.

Dec 05, 2022

Neuroinflammation is one of the most important processes in secondary injury after traumatic brain injury (TBI). Triggering receptor expressed on myeloid cells 2 (TREM2) has been proven to exert neuro...

TREM2 activation alleviates neural damage via Akt/CREB/BDNF signalling after traumatic brain injury in mice.

Dec 05, 2022

Neuroinflammation is one of the most important processes in secondary injury after traumatic brain injury (TBI). Triggering receptor expressed on myeloid cells 2 (TREM2) has been proven to exert neuro...

The dynorphin/kappa opioid receptor mediates adverse immunological and behavioral outcomes induced by repetitive blast trauma.

Dec 05, 2022

Adverse pathophysiological and behavioral outcomes related to mild traumatic brain injury (mTBI), posttraumatic stress disorder (PTSD), and chronic pain are common following blast exposure and contrib...

Pertuzumab, trastuzumab, and docetaxel for Chinese patients with previously untreated HER2-positive locally recurrent or metastatic breast cancer (PUFFIN): final analysis of a phase III, randomized, double-blind, placebo-controlled study.

Dec 05, 2022

PUFFIN (NCT02896855), a Chinese bridging study in patients with previously untreated HER2-positive locally recurrent or metastatic breast cancer, assessed consistency of efficacy and safety of pertuzu...

Pressure Injury Risk Factors in Critically Ill Patients in a Coronary Care Unit

Nov 25, 2022

For a study, researchers sought to assess the prevalence of pressure injuries (PIs) in patients in the coronary care unit (CCU), the features of PIs, and the risk factors connected with them. The m...

How Nutrition Impacts Pressure Injury Prevention and Treatment in Critically Ill Patients

Nov 25, 2022

To avoid and cure pressure injuries (PIs) in critically sick adult patients, it was important to study the relevant scientific research on nutrition. Scientific Electronic Library Online (SciELO), ...

Analysis of Vasopressor Dose and Incidence Pressure Injuries in Critically Ill Patients

Nov 24, 2022

For a study, researchers sought to assess the risk variables for using vasopressors and the emergence of hospital-acquired pressure injuries (HAPIs). In a 12-bed medical ICU at a community hospital...

Comprehensive Treatment for Leg Ulcers in Ozone Therapy

Nov 24, 2022

Numerous medical specialties are interested in ozone therapy as a kind of treatment. In the discipline of angiology, infected wounds that are challenging to heal are treated with ozone. For a study, r...

Preventing Radiation Dermatitis After Effects of Sanyrene Liquid Dressing

Nov 24, 2022

For a study, researchers sought to evaluate the effectiveness of the Sanyrene liquid dressing (Urgo Medical) in shielding cancer patients from radiation dermatitis (RD) following radiotherapy. For ...

Analysis of Second-Degree Burns and Aloe Vera

Nov 23, 2022

Aloe vera is a readily available, affordable adjuvant for wound treatment with a low-risk profile. Although it has been used for many years to treat different kinds of wounds, published studies on its...

A Systematic Review of Maintaining and Promoting Skin Integrity in End-of-Life Care

Nov 23, 2022

For a study, researchers sought to comprehensively assess the data supporting guidelines for promoting and preserving skin integrity in end-of-life care. A combination of key phrases, including end...

Legal Claims Characterization that Involves Patients with Pyoderma Gangrenisum

Nov 23, 2022

To understand the legal challenges patients with pyoderma gangrenosum (PG) confront, it was necessary to research the litigation literature in the area. PG patients were personally involved in all ...

Lab Test to Compare Energy-Stretch Properties of Two Compression Bandage Systems

Nov 22, 2022

For a study, researchers sought to employ a laboratory bench test to evaluate the properties of two commercially available compression systems: the dual-compression bandage system (DCS) and the tradit...

Analyzing pNPWT Effects for High-Risk Wounds in Colorectal Cancer Surgery

Nov 22, 2022

For a study, researchers sought to ascertain the impact of prophylactic negative-pressure wound therapy (pNPWT) in patients who received colorectal cancer surgery and were at high risk for surgical wo...

How Morphometry & Sacrococcygeal Skeletal Morphology Affect Adult Pressure Injury Formation?

Nov 22, 2022

For a study, researchers sought to identify the precise location of the pressure injury (PI), ascertain if sacrococcygeal skeletal morphology and morphometry traits were potential inherent risk factor...

Predictive Response Factors for High-Flow Nasal Cannula Treatment of COVID-19 Patients

Nov 18, 2022

Many patients admitted to the intensive care unit (ICU) with hypoxemic respiratory failure due to COVID-19 pneumonia have benefited greatly from oxygen therapy. As the present pandemic unfolds, there ...

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