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Critical Care General

Patients Evaluations for Acute Respiratory Distress Syndrome

Jun 16, 2022

For a study, researchers sought to observe whether the patients who met the Berlin criteria for ARDS and were admitted over 18 months in 2 intensive care units (ICU) at a university-affiliated hospita...

Outcomes of Cardiac Arrest Predict By N20 & P25 Amplitudes

Jun 16, 2022

For a study, researchers sought to see if the amplitudes of 2 somatosensory evoked potentials (SSEP) responses, N20-baseline (N20-b) and N20–P25, were predictive of neurological prognosis in comatos...

The Relationship Between the Outcome of COVID-19 Patients in Intensive Care & Activities of Daily Living

Jun 16, 2022

For a study, researchers sought to investigate the connection of Activities of Daily Living (ADL) with the outcome in the vulnerable patient group of post hoc analysis. The COVIP research was a prospe...

In Septic Mechanically Ventilated Patients, Severe But Reversible Diaphragm Dysfunction Occurs

Jun 16, 2022

For a study, researchers sought to describe the diaphragm function time course in mechanically ventilated septic and non-septic patients. Secondary analysis of 2 prospective observational studies of m...

Increased progranulin as an independent predictive biomarker for poor prognosis in sepsis.

May 23, 2022

Recently, many diagnostic biomarkers were reported, but each had its own limitation. However, there is a need for an effective sensitivity and specificity of biomarker in diagnosis and prognosis of se...

Knee Arthrodesis Using a Compression Clamp and a Single-Plane External Fixator to Treat Infection.

May 23, 2022

In patients with knee infection, arthrodesis by external fixation is a limb-salvage procedure appropriate in highly selected patients. No hardware that might lead to infection is left in situ. However...

Treatment Trends and Inpatient Mortality in Isolated Severe Traumatic Brain Injury Using the National Trauma Data Bank.

May 23, 2022

Severe traumatic brain injury remains a leading cause of morbidity and mortality. Despite recommendations from the Brain Trauma Foundation, there is wide variability in treatment paradigms for severe ...

Left atrial disease and left atrial reverse remodeling across different stages of heart failure development and progression: a new target for prevention and treatment.

May 23, 2022

The left atrium is a dynamic chamber with peculiar characteristics. Stressors and disease mechanisms may deeply modify its structure and function, leading to left atrial remodeling and disease. Left a...

How to Best Prevent Central Line-Associated Bloodstream Infections

May 18, 2022

The following was originally posted to the University of Nebraska Medical Center Division of Infectious Diseases blog.     Dr. Rupp recently assisted in the creation of ne...

A standardized implementation of multicenter quality improvement program of very low birth weight newborns could significantly reduce admission hypothermia and improve outcomes.

May 16, 2022

Admission hypothermia (AH, < 36.5℃) remains a major challenge for global neonatal survival, especially in developing countries. Baseline research shows nearly 89.3% of very low birth weight (...

Innate immune signalling and immunothrombosis: New insights and therapeutic opportunities.

May 16, 2022

Activation of the coagulation cascade is a critical, evolutionarily conserved mechanism that maintains haemostasis by rapidly forming blood clots in response to blood-borne infections and damaged bloo...

The mortality predicting ability of chest X-ray severity scoring systems in Covid-19 pneumonia.

May 16, 2022

Although several chest X-ray (CXR) severity scoring systems are in use to assess Covid-19 pneumonia (CP), inhomogeneity has been observed among the assessment methodologies.To describe and validate se...

Protein kinase G phosphorylation of Chip protects ovariectomized females from myocardial infarction.

May 16, 2022

Proteotoxicity from insufficient clearance of misfolded/damaged proteins exacerbates cardiac functional decline following a myocardial infarction (MI). Estrogen is known to play a crucial role in the ...

Myeloid Expressed Epidermal Growth Factor Receptor (EGFR) is Critical to Heart Homeostasis and Limits Adverse Outcomes Following Ischemic Attack.

May 16, 2022

The healthy heart comprises immune cells, mainly macrophages of differing class and origin. While these myeloid cells remain an area of continuous investigation, we have come to appreciate that a subs...

Effectiveness of an Active and Continuous Surveillance Program for Intensive Care Units Infections Based on the EPIC III (Extended Prevalence of Infection in Intensive Care) Approach.

May 16, 2022

We evaluated the effectiveness of the Extended Prevalence of Infection in Intensive Care (EPIC) III data collection protocol as an active surveillance tool in the eight Intensive Care Units (ICUs) of ...

Rescue venovenous extracorporeal membrane oxygenation for the deterioration of acute respiratory distress syndrome in pediatric liver transplantation.

May 16, 2022

Twenty percent of pediatric patients with BA develop ACLF with increased mortality while awaiting LT. Respiratory complications are common in pediatric ACLF and are associated with increased morbidity...

Equity and Disparities in Diagnosis, Management, and Research of Post-Traumatic Headache.

May 16, 2022

There are notable health disparities and inequities in individuals with traumatic brain injury (TBI) and concussion by race, ethnicity, gender, socioeconomic status, and geography. This review will ev...

Prediabetes and insulin resistance in a population of patients with heart failure and reduced or preserved ejection fraction but without diabetes, overweight or hypertension.

May 16, 2022

The relationships between glucose abnormalities, insulin resistance (IR) and heart failure (HF) are unclear, especially regarding to the HF type, i.e., HF with reduced (HFrEF) or preserved (HFpEF) eje...

Clinical Outcomes of Early Vs. Late Tracheostomy in Coronavirus Disease Patients

May 11, 2022

From January 1, 2020, to December 1, 2021, Pubmed, Cochrane Library, Scopus, and Embase were searched to find relevant papers comparing outcomes of COVID-19 patients undergoing early and late tracheos...

Continuous-Wave Doppler Ultrasound Monitor & Echocardiography in Cardiac Postoperative Pediatric Patients

May 11, 2022

In the immediate post-operative course of young, congenital heart repaired patients, non-invasive cardiac output (CO) measurements were critical. In pediatric intensive care units (PICUs), the adoptio...

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