Feb 26, 2024

Enrollment into critical care clinical trials is often hampered by the need to rely on surrogate decision-makers. To identify potential interventions facilitating enrollment into critical care clinica...

Feb 19, 2024

The two latest studies on prolonged versus intermittent use of β-lactam antibiotics in patients with sepsis did not reach consistent conclusions, further contributing to the controversy surrounding t...

Feb 19, 2024

Tetrahydrocurcumin (THC) and microglial polarization play crucial roles in neuroprotection during traumatic brain injury (TBI). However, whether THC regulates microglial polarization in TBI is unknown...

Feb 19, 2024

The ability to allocate visual attention is known to be impaired in patients with mild traumatic brain injury (mTBI). In the present study, we investigated a possible neural correlate of this cognitiv...

Feb 19, 2024

In adulthood, individuals with type 1 diabetes mellitus may develop a condition of heart failure with preserved ejection fraction. However, subclinical changes to the heart in diabetes are likely to o...

Feb 19, 2024

Pre-existing malnutrition in critically ill patients is associated with adverse clinical outcomes. Malnutrition can be diagnosed with the Global Leadership Initiative on Malnutrition using parameters ...

Feb 19, 2024

Clinicians, patients, and families alike perceive a need to improve how goals of care (GOC) decisions occur in chronic critical illness (CCI) but little is currently known about this decision making p...

Feb 12, 2024

Due to a lack of donor grafts, steatotic livers are used more often for liver transplantation (LT). However, steatotic donor livers are more sensitive to ischemia-reperfusion (IR) injury and have a wo...

Feb 12, 2024

Mendelian susceptibility to mycobacterial diseases (MSMD) is a rare clinical syndrome characterized by vulnerability to weakly virulent mycobacterial species, including Bacillus Calmette-Guérin (BCG)...

Feb 12, 2024

The positive detection rate of blood metagenomic next-generation sequencing (mNGS) was still too low to meet clinical needs, while pus from the site of primary infection may be advantageous for identi...

Feb 12, 2024

Limited evidence exists regarding the impact of adherence to diverse tuberculosis preventive therapy (TPT) regimens on TB risk in individuals with tuberculosis infections (TBI). This study aimed to ex...

Feb 12, 2024

Takotsubo cardiomyopathy (TTC), also known as stress-induced cardiomyopathy, resembles acute heart failure syndrome but lacks disease-specific diagnosis and treatment strategies. TTC accounts for appr...

Feb 12, 2024

We conducted an implementation planning process during the pilot phase of a pragmatic trial, which tests an intervention guided by artificial intelligence (AI) analytics sourced from noninvasive monit...

Feb 05, 2024

Histidine-rich glycoprotein has been reported as an anti-inflammatory glycoprotein that inhibits acute lung injury in mice with sepsis and as a prognostic biomarker in patients with sepsis. We investi...

Feb 05, 2024

Dealing with newborns' health is a delicate matter since they cannot express needs, and crying does not reflect their condition. Although newborn cries have been studied for various purposes, there is...

Feb 05, 2024

Acute lung injury (ALI) is a serious complication that may accompany severe pneumonia in children. Derived from exosomes of human umbilical cord mesenchymal stem cell exosome (HucMSC-Exo) can contribu...

Feb 05, 2024

To determine the occurrence of Group B (GBS) infection in neonates and its associated risk factors in Al-Madinah Al-Munawarah, Saudi Arabia.This retrospective study was carried out at the Maternity a...

Feb 05, 2024

Different risk factors affect the intensive care unit (ICU) stay after cardiac surgery. This study aimed to evaluate these risk factors.A retrospective analysis was conducted on clinical, operative, a...

Feb 05, 2024

This study aims to evaluate effect of 4-factor PCC on outcomes of severe TBI patients on preinjury anticoagulants undergoing craniotomy/craniectomy.In this analysis of 2018-2020 ACS-TQIP, patients wit...

Feb 05, 2024

Monocytes represent key cellular elements that contribute to the neurological sequela following brain injury. The current study reveals that trauma induces the augmented release of a transcriptionally...