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Critical Care General

High-Flow Nasal Cannula Reduces Effort of Breathing But Not Consistently via Positive End-Expiratory Pressure.

Apr 11, 2022

High-flow nasal cannula (HFNC) therapy reduces the effort of breathing in patients with bronchiolitis, but the mechanisms are not understood. Theorized mechanisms include dead space washout and positi...

The long-term effect of exposure to respirable particulate matter on the incidence of myocardial infarction: a systematic review and meta-analysis study.

Apr 04, 2022

Although several studies have investigated the long-term association of respirable particulate matter (PM ≤ 10 µm) with the incidence of myocardial infarction (MI), this association is inconcl...

Percutaneous Endoscopic Gastrostomy Tube Timing in Head and Neck Cancer Surgery.

Apr 04, 2022

To examine outcomes and complications in patients receiving a percutaneous endoscopic gastrostomy (PEG) tube on the same day of head and neck cancer (HNC) surgery versus later in hospitalization.The 2...

Risk factors for septic arthritis and multiple arthroscopic washouts: minimum 2-year follow-up at a major trauma centre.

Apr 04, 2022

Septic arthritis (SA) is a dangerous condition that requires emergency treatment. Managed by culture-specific antibiotics, irrigation, and debridement (I&D), some patients require repeat surgical ...

Sleep Dysfunction in Adolescents With Prolonged Postconcussion Symptoms: A Reciprocal Coupling of Traumatic Brain Injury and Sleep-Related Problems.

Apr 04, 2022

Concussions are often neglected injuries that affect children and adolescents. Two physiological responses to a concussion are an ionic flux and an increased indiscriminate release of glutamate, which...

Susceptibility to epilepsy after traumatic brain injury is associated with preexistent gut microbiome profile.

Apr 04, 2022

We examined whether post-traumatic epilepsy (PTE) is associated with measurable perturbations in gut microbiome.Adult Sprague-Dawley rats were subjected to Lateral Fluid Percussion Injury (LFPI). PTE ...

Cor triatriatum dexter of unusual morphology in a miniature schnauzer.

Apr 04, 2022

A five-year-nine-month-old, male entire, miniature schnauzer presented for further investigation of pleural effusion. Echocardiography revealed a perforated membrane dividing the right atrium into two...

Higher serum occludin after successful reperfusion Is associated with early neurological deterioration.

Mar 28, 2022

Early neurological deterioration (END) is an important factor that affects prognosis in patients with acute ischemic stroke. We explored the relationship between serum occludin levels after successful...

Implication of IGF1R signaling in the protective effect of Astragaloside IV on ischemia and reperfusion-induced cardiac microvascular endothelial hyperpermeability.

Mar 28, 2022

Myocardial ischemia-reperfusion (I/R) causes damage to coronary capillary endothelial barrier and microvascular leakage (MVL), aggravating tissue injury and heart dysfunction. However, the effective s...

An extensive computational study to identify potential inhibitors of Acyl-homoserine-lactone synthase from Acinetobacter baumannii (strain AYE).

Mar 28, 2022

A member of the ESKAPE family of pathogens, A. baumannii, is an opportunistic gram-negative multidrug-resistant bacterium. A. baumannii is a ubiquitous coccobacillus involved in various hospital-relat...

CRISPR-Cas9 Mediated Knockout of Gene for Overexpression of Streptokinase in .

Mar 28, 2022

Streptokinase is an enzyme that can break down the blood clots in some cases of myocardial infarction (heart attack), pulmonary embolism, and arterial thromboembolism. Demand for streptokinase is high...

Allogeneic blood transfusions and infection risk in lumbar spine surgery: An American College of Surgeons National Surgery Quality Improvement Program Study.

Mar 28, 2022

Allogenic blood transfusions can lead to immunomodulation. Our purpose was to investigate whether perioperative transfusions were associated with postoperative infections and any other adverse events ...

Zero retinal vein pulsation amplitude extrapolated model in non-invasive intracranial pressure estimation.

Mar 28, 2022

Intracranial pressure (ICP) includes the brain, optic nerve, and spinal cord pressures; it influences blood flow to those structures. Pathological elevation in ICP results in structural damage through...

Intellectual/developmental disabilities among people incarcerated in federal correctional facilities in Ontario, Canada: Examining prevalence, health and correctional characteristics.

Mar 28, 2022

There is little research with people who experience intellectual/developmental disabilities and imprisonment.The study linked health and correctional data to examine prevalence of intellectual/develop...

Outcomes of CMS-mandated fluid administration among fluid-overloaded patients with sepsis: A systematic review and meta-analysis.

Mar 28, 2022

The outcomes of large-volume IVF administration to septic shock patients with comorbid congestive heart failure (CHF) and/or end-stage renal disease (ESRD) are uncertain and widely debated in the exis...

High Flow Nasal Cannula Reduces Effort of Breathing but Not Consistently Via Positive End-Expiratory Pressure.

Mar 28, 2022

High flow nasal cannula (HFNC) therapy reduces effort of breathing in bronchiolitis, but the mechanisms are not understood. Theorized mechanisms include dead space washout and positive end-expiratory ...

COVID-19 Acute Respiratory Distress Syndrome With Symptoms of PTSD in Family Members After ICU Discharge

Mar 24, 2022

For a study, researchers sought to investigate the relationship between patient hospitalization for COVID-19 ARDS vs ARDS from other causes and the risk of posttraumatic stress disorder (PTSD)–relat...

Biogeochemical impacts of sewage effluents in predominantly rural river catchments: Are point source inputs distinct to background diffuse pollution?

Mar 21, 2022

Discharge of treated sewage effluent to rivers can degrade aquatic ecosystem quality, interacting with multiple stressors in the wider catchment. In predominantly rural catchments, the river reach inf...

JAK2V617F Is a Risk Factor for TIA/Stroke in Young Patients.

Mar 21, 2022

The objective of this study was to assess the risk of arterial thrombosis in patients who harbor the allele burden ≥1% detected during workup for myeloproliferative neoplasms (MPNs). We conducted a...

Retrospective Identification of Infection in the Emergency Department: A Significant Challenge in Sepsis Clinical Trials.

Mar 21, 2022

This study examined three methods for retrospectively identifying infection in emergency department (ED) patients: modified objective definitions of infection (MODI) from the CDC/NHSN, physician adjud...

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