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Critical Care General

A Clinical Diagnostic Study: Fibulin-2 is a Novel Promising Biomarker for Predicting Infection.

Mar 21, 2022

Infection remains a major cause of morbidity and mortality in hospital. As uncontrolled early infection may develop into systemic infection and eventually progress to sepsis, it is important to addres...

Benign Metastasizing Leiomyomatosis to the Skin and Lungs, Intravenous Leiomyomatosis, and Leiomyomatosis Peritonealis Disseminata: A Series of Five Cases.

Mar 21, 2022

Benign metastasizing leiomyomatosis (BML) is a rare disease that typically occurs in women with a history of uterine leiomyomatosis. Benign metastasizing leiomyomatosis occurs more frequently in the l...

Effect of Secukinumab on Traditional Cardiovascular Risk Factors and Inflammatory Biomarkers: Post Hoc Analyses of Pooled Data Across Three Indications.

Mar 21, 2022

Psoriasis, psoriatic arthritis (PsA), and axial spondyloarthritis (axSpA) are chronic immune-mediated inflammatory diseases (IMIDs) associated with cardiovascular (CV) disease. High-sensitivity C-reac...

"Pulmonary and Critical Care Considerations for E-cigarette, or Vaping, Product Use-Associated Lung Injury (EVALI)".

Mar 21, 2022

In 2019, the United States experienced a nationwide outbreak of e-cigarette, or vaping, product use-associated lung injury (EVALI). More than half of these patients required admission to an intensive ...

Chronic Dyspnea with Raynaud's Phenomenon and Elevated ANA: A Diagnosis of Systemic Sclerosis Sine Scleroderma.

Mar 14, 2022

Systemic sclerosis (SSc) should be considered in all patients initially diagnosed with idiopathic interstitial lung disease (ILD), even in the absence of classical scleroderma cutaneous features. Syst...

Heart rate trajectories in patients recovering from acute myocardial infarction: A longitudinal analysis of Apple Watch heart rate recordings.

Mar 14, 2022

Using mobile health, vital signs such as heart rate (HR) can be used to assess a patient's recovery process from acute events including acute myocardial infarction (AMI).We aimed to characterize clini...

Transcriptional switch of hepatocytes initiates macrophage recruitment and T cell suppression in endotoxemia.

Mar 14, 2022

The liver plays crucial roles in the regulation of immune defense during acute systemic infections. However, the roles of liver cellular clusters and intercellular communication in the progression of ...

Outcome and Predictors of Septic Failure following Total Joint Arthroplasty for Prior Septic Arthritis of Hip and Knee joint.

Mar 14, 2022

Arthroplasty patients with prior septic arthritis are at high risk of developing periprosthetic joint infection (PJI). The aims of this study are to investigate the outcome and predictors of septic fa...

Hypertension and advanced age increase the risk of cognitive impairment after mild traumatic brain injury: A registry-based study.

Mar 14, 2022

As the global population ages, the incidence of traumatic brain injury (TBI) increases. While mild TBI can impair the cognitive function of older adults, the cause and background of mild TBI-induced c...

CHARACTERIZATION OF THE RIGHT VENTRICULAR SUBSTRATE PARTICIPATING IN POST INFARCTION VENTRICULAR TACHYCARDIA.

Mar 14, 2022

The right ventricle (RV) is uncommonly implicated in post-infarction ventricular tachycardia (VT). The prevalence and features of RV substrate participating in post-infarction VT are undefined.To char...

"Pulmonary and Critical Care Considerations for E-cigarette, or Vaping, Product Use-Associated Lung Injury (EVALI)".

Mar 14, 2022

In 2019, the United States experienced a nationwide outbreak of e-cigarette, or vaping, product use-associated lung injury (EVALI). More than half of these patients required admission to an intensive ...

Psychiatric Outcomes in Intensive Care Unit Patients with Family Visitation: A Population-based Retrospective Cohort Study.

Mar 14, 2022

Lack of family visitation in ICU can have long-term consequences on ICU patients post-discharge. Efect of family visitation on the incidence of patient psychiatric disorders is unknown.What is the ass...

Progressive Small-Vessel Strokes Following Antiretroviral Therapy in a Patient with Acquired Immunodeficiency Syndrome.

Mar 07, 2022

We report a case of a 59-year-old man with human immunodeficiency virus (HIV)/ acquired immunodeficiency syndrome (AIDS) who developed multiple small-vessel strokes during the immune reconstitution ph...

Scutellarin potentiates vancomycin against lethal pneumonia caused by methicillin-resistant Staphylococcus aureus through dual inhibition of sortase A and caseinolytic peptidase P.

Mar 07, 2022

The strategy of targeting virulence factor has received great attention as it barely develops bacterial resistance. Sortase A (SrtA) and caseinolytic peptidase P (ClpP), as important virulence factors...

[Glucose, Lactate, NGAL and Coefficient of Energy Balance in Synovial Fluid in Patients with Hip and Knee Prosthetic Joint Infection].

Mar 07, 2022

PURPOSE OF THE STUDY Laboratory methods are central to prosthetic joint infection (PJI) diagnosis. Most research teams focus on detection of specific inflammatory markers, causative pathogens, or on a...

Deep Learning to Predict Traumatic Brain Injury Outcomes in the Low-Resource Setting.

Mar 07, 2022

Traumatic brain injury (TBI) disproportionately affects low- and middle-income countries (LMICs). In these settings, accurate patient prognostication is both difficult and essential for high-quality p...

Patterns of Care for First-detected Atrial Fibrillation: Insights from the Get With The Guidelines Atrial Fibrillation Registry.

Mar 07, 2022

Despite multiple trials comparing rate with rhythm control, there is no consensus on optimal management of first-detected atrial fibrillation (AF).We analyzed current patterns of care for first-detect...

Association of hypoxic ischemic brain injury on early CT after out of hospital cardiac arrest with neurologic outcome.

Feb 28, 2022

This study aimed to describe the prevalence of hypoxic-ischemic brain injury (HIBI) on head CT (HCT) obtained within two hours of return of spontaneous circulation (ROSC) care in the Emergency Departm...

Effects of azumolene on arrhythmia substrate in a model of recurrent long-duration ventricular fibrillation.

Feb 28, 2022

Proarrhythmic risk of conventional anti-arrhythmic agents is linked to unintended modulation of membrane voltage dynamics. We have demonstrated that the anti-fibrillatory effect of azumolene is mediat...

Structure-based molecular characterization of the LltR transcription factor from Listeria monocytogenes.

Feb 28, 2022

Listeria monocytogenes is a psychrotrophic food-borne pathogenic bacterium that causes listeriosis. Due to its unusual adaptation, an ability to grow at extended temperatures ranging from 4 to 45 °C...

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