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Critical Care General

Development of Liposome-Based Immunoassay for the Detection of Cardiac Troponin I.

Nov 29, 2021

Cardiovascular diseases (CVDs) are one of the foremost causes of mortality in intensive care units worldwide. The development of a rapid method to quantify cardiac troponin I (cTnI)-the gold-standard ...

Is early activity resumption after paediatric concussion safe and does it reduce symptom burden at 2 weeks post injury? The Pediatric Concussion Assessment of Rest and Exertion (PedCARE) multicentre randomised clinical trial.

Nov 29, 2021

Investigate whether resuming physical activity (PA) at 72 hours post concussion is safe and reduces symptoms at 2 weeks, compared with resting until asymptomatic.Real-life conditions, multicentre, s...

Traumatic brain injury in the presence of Aβ pathology affects neuronal survival, glial activation and autophagy.

Nov 29, 2021

Traumatic brain injury (TBI) presents a widespread health problem in the elderly population. In addition to the acute injury, epidemiological studies have observed an increased probability and earlier...

Relation between brain natriuretic peptide and delayed cerebral ischemia in patients with aneurysmalsubarachnoid hemorrhage.

Nov 29, 2021

Brain natriuretic peptide (BNP), often used to evaluate degree of heart failure, has been implicated in fluid dysregulation and inflammation in critically-ill patients. Twenty to 30% of patients with ...

A multivariate model for successful publication of intensive care medicine randomized controlled trials in the highest impact factor journals: the SCOTI score.

Nov 29, 2021

Critical care randomized controlled trials (RCTs) are often published in high-impact journals, whether general journals [the New England Journal of Medicine (NEJM), The Lancet, the Journal of the Amer...

In vitro synergistic effect of minocycline combined with antifungals against Cryptococcus neoformans.

Nov 22, 2021

Cryptococcus neoformans infections occur in immunocompromised patients, especially those with HIV infection, chemoradiotherapy after cancer, and organ transplantation. Infection can cause pneumonia an...

Nineteen-Year Associations Between Three Diet Quality Indices and All-Cause And Cardiovascular Disease Mortality: The Australian Diabetes, Obesity And Lifestyle Study.

Nov 22, 2021

Examining a variety of diet quality methodologies will inform best practice use of diet quality indices for assessing all-cause and CVD mortality.To examine the association between three diet quality ...

Trends in antimicrobial resistance in bloodstream infections at a large tertiary-care hospital in China: a 10-year retrospective study (2010-2019).

Nov 22, 2021

Bloodstream infections (BSIs) are considered as a major cause of morbidity and mortality all over the world. The purpose of this study was to explore the distribution and antimicrobial resistance tren...

mTOR pathway: A potential therapeutic target for spinal cord injury.

Nov 22, 2021

Spinal cord injury (SCI) is the most common disabling spinal injury, and the complex pathological process can eventually lead to severe neurological dysfunction. Many studies have reported that the ma...

Assessment of longitudinal systolic function using tissue motion annular displacement in dogs with degenerative mitral valve disease.

Nov 22, 2021

Although degenerative mitral valve disease (DMVD) is essentially a disorder of the valve, the progression of the disease leads to structural myocardial changes that may compromise left ventricular sys...

Aspirin as a Treatment for Acute Respiratory Distress Syndrome: a randomised placebo controlled clinical trial.

Nov 22, 2021

There is no pharmacological treatment for the acute respiratory distress syndrome (ARDS). Platelets play an important role in the pathophysiology of ARDS. Pre-clinical, observational and clinically re...

[Comparative study of CT relative enhancement value and subjective visual evaluation for intestinal ischemia in patients with closed loop obstruction].

Nov 15, 2021

To compare and evaluate the diagnostic performance of visual evaluation and CT maximal density relative enhancement value in the diagnosis of intestinal ischemia complication in patients with closed ...

The contribution of neuropilin-1 in the stability of CD4 CD25 regulatory T cells through the TGF-β1/Smads signaling pathway in the presence of lipopolysaccharides.

Nov 15, 2021

This study investigates the synergistic effect of TGF-β1 and Nrp-1 on CD4 CD25 T ' stabilization, and the associated pathways of signal transduction, in vitro models in the presence of LPS.Spleen CD4...

Socioeconomic status and parent perceptions about the costs and benefits of youth sport.

Nov 15, 2021

Describe what costs and benefits parents across the socioeconomic spectrum weight most heavily when making decisions about sport participation for their children.Cross-sectional survey of a nationally...

Deficits Found in Identification of Patient Goals Post-Sepsis Hospitalization

Nov 11, 2021

“Growing evidence indicates that survivors of sepsis face multiple health challenges after their initial hospitalization, along with high rates of healthcare utilization and mortality,” explains S...

Benefits and safety of transdermal glyceryl trinitrate in acute stroke: a systematic review and meta-analysis of randomised trials.

Nov 08, 2021

Transdermal glyceryl trinitrate (GTN) has potential beneficial properties in acute stroke including intracerebral hemorrhage (ICH) and possible clinical benefits suggested in ultra-early stroke (≤ 6...

Clinical characteristics and outcome of 125 polymicrobial bloodstream infections in hematological patients: an 11-year epidemiologic survey.

Nov 08, 2021

Polymicrobial bloodstream infections (pBSI) occurring in hematological patients are still poorly understood, and specific information are very limited.In this epidemiologic survey, we describe clinica...

Application of phosphorus loading models to understand drivers of eutrophication in a complex rural lake-watershed system.

Nov 08, 2021

Several lakes in southwestern Nova Scotia, Canada have experienced reoccurring algal blooms and possess concentrations of phosphorus (P) that are in the eutrophic to hypereutrophic range (>35 μg/L...

Subclinical Vascular Brain Lesions in Young Adults With Acute Ischemic Stroke.

Nov 08, 2021

Subclinical vascular brain lesions are highly prevalent in elderly patients with stroke. Little is known about predisposing factors and their impact on long-term outcome of patients with stroke at a y...

Prognostic value of CHA2DS2-VASc score in predicting high SYNTAX score and in-hospital mortality for non-ST elevation myocardial infarction in patients without atrial fibrillation.

Nov 08, 2021

To evaluate the prognostic value of preprocedural CHA2DS2-VASc [congestive heart failure, hypertension, age ≥75 years (doubled), diabetes mellitus, previous stroke or transient ischemic attack (TIA)...

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