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Critical Care General

Ceftolozane/tazobactam for refractory P. aeruginosa endocarditis: A case report and pharmacokinetic analysis.

Sep 20, 2021

We describe a case of a 48 years old male with left sided endocarditis and septic emboli secondary to a Pseudomonas aeruginosa strain that developed resistance to other β-lactam antibiotics during th...

Pericyte-derived fibrotic scarring is conserved across diverse central nervous system lesions.

Sep 20, 2021

Fibrotic scar tissue limits central nervous system regeneration in adult mammals. The extent of fibrotic tissue generation and distribution of stromal cells across different lesions in the brain and s...

Blocking receptor for advanced glycation end products (RAGE) or toll-like receptor 4 (TLR4) prevents posttraumatic epileptogenesis in mice.

Sep 20, 2021

Effective treatment for the prevention of posttraumatic epilepsy is still not available. Here, we sought to determine whether blocking receptor for advanced glycation end products (RAGE) or toll-like ...

Wound care management: tracheostomy and gastrostomy.

Sep 20, 2021

Percutaneous dilatational tracheostomy (PDT) and percutaneous endoscopic gastrostomy (PEG) tube placements are routine procedures performed in the intensive care units (ICUs). They are performed to fa...

Ultrasound use in the ICU for interventional pulmonology procedures.

Sep 20, 2021

Critical care ultrasound has shifted the paradigm of thoracic imaging by enabling the treating physician to acquire and interpret images essential for clinical decision-making, at the bedside, in real...

Coagulation Studies

Sep 17, 2021

This study states that Anticoagulation plays a key role in the management of children supported with extracorporeal membrane oxygenation. However, the ideal strategy for monitoring anticoagulation rem...

Anticoagulation And Transfusion

Sep 17, 2021

This study states that Eighty-three medical directors at 108 centers responded. After removing four duplicate responses, 79 surveys were analyzed. Seventy-nine percent (n = 62) report a written extrac...

Continuous Prediction Of Mortality

Sep 17, 2021

This study aims to develop, as a proof of concept, a previously described (10–13) deep learning methodology, namely a long short-term memory (LSTM) recurrent neural network (RNN) to continuously ass...

Neurologic Manifestations Of COVID-19

Sep 17, 2021

This study states that Cellular invasion by the SARS-CoV-2 begins with binding of the viral spike protein to a transmembrane receptor, followed by viral membrane fusion with the cellular membrane afte...

Pandemic Spawning An Infodemic

Sep 17, 2021

This study states that the coronavirus disease 2019 (COVID-19) pandemic continues to have a devastating impact on all aspects of life, worldwide. It has been challenging. Professionally, all aspects o...

Association Of Acute Kidney Injury Duration

Sep 16, 2021

This study claims that Acute kidney injury was categorized based on duration to transient (48 hr or less) or persistent (more than 48 hr). Transient acute kidney injury occurred in 240 children (77.9%...

Optimal Timing of Tracheostomy

Sep 16, 2021

After stratifying by traumatic brain injury diagnosis, we compared ICU and hospital length of stay, pneumonia, and discharge disposition of patients with tracheostomy prior to three cut points (3, 7, ...

Characteristics Of Burn-Injured Children

Sep 16, 2021

This study states that Cutaneous burns were recorded in 92.1% of patients, mouth/pharynx burns in 5.8%, inhalation injury in 5.1%, and larynx/trachea/lung burns in 4.5%. Among those with an etiology r...

Coronavirus Disease 2019

Sep 16, 2021

The aim is To compare clinical characteristics and outcomes of children admitted to the PICU for severe acute respiratory syndrome coronavirus 2–a related illness with or without multisystem inflamm...

Clinical Care Strategies

Sep 16, 2021

This study states that children with complex chronic conditions often receive inpatient and end-of-life care in the ICU, yet little is known about the clinical care strategies that best support this u...

Thromboembolic Complications

Sep 15, 2021

The objective of this study is to Pediatric venous thromboembolic events are commonly associated with in situ central venous catheters. The risk for severe venous thromboembolism increases if a larger...

End-Of-Life Care In Taiwan

Sep 15, 2021

This study states that In the whole cohort, 22 of 316 patients (7%) were determined as “death by neurologic criteria”. There were 94 of 316 patients (30%) who had an event needing cardiopulmonary ...

Point-Of-Care Lung

Sep 15, 2021

The aim is to Determine the sensitivity and specificity of point-of-care lung ultrasound in identifying the etiology of acute respiratory failure at admission to the PICU. Children older than 37 week...

Pediatric Severe Sepsis

Sep 15, 2021

Pediatric sepsis remains a major health problem and is a leading cause of death and long-term disability worldwide. This study aims to characterize epidemiologic, therapeutic, and outcome features of ...

Cardiopulmonary Bypass

Sep 15, 2021

This study states that Soluble MER has emerged as a potential biomarker for delayed resolution of inflammation after myocardial injury and a therapeutic target to reduce cardiac-related morbidity and ...

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