Aug 26, 2021

Clinical practice guidelines support sustained use of renin-angiotensin-aldosterone-system (RAAS) inhibitors over time in heart failure with reduced ejection fraction, yet few data are available regar...

Aug 26, 2021

Heart failure and sleep disordered breathing have been increasingly recognized as co-occurring conditions. Their bidirectional relationship warrants investigation into whether heart failure therapy im...

Aug 26, 2021

Perceived health is one of the strongest determinants of subjective well-being, but it has received little attention among survivors of acute respiratory distress syndrome (ARDS).How well do self-repo...

Aug 26, 2021

Critically ill adults are at increased risk of venous thromboembolism (VTE), including deep venous thrombosis (DVT), and pulmonary embolism (PE). Various agents exist for venous thromboprophylaxis in ...

Aug 23, 2021

Exercise therapy and neuromuscular electrical stimulation (NMES) during the initial 14 days after stroke may benefit recovery of gait. We aimed to determine whether poststroke NMES of vastus medial an...

Aug 23, 2021

During ischemia reperfusion (IR) injury, high mobility group box 1 (HMGB1), a chromatin binding protein, is released from necrotic cells and triggers inflammatory responses. We assessed the therapeuti...

Aug 23, 2021

Early recognition of sepsis and a prompt initiation of goal-directed therapy is important for sepsis survival. Little is known about the impact of early recognition of sepsis in the out-of-hospital se...

Aug 23, 2021

Nocardia is an opportunistic pathogen, which occurs in patients with autoimmune diseases and immune dysfunction, and can cause bacteremia and other life-threatening complications. The clinical manifes...

Aug 23, 2021

To assess pathogen distributions and antimicrobial sensitivity characteristics in non-small cell lung cancer (NSCLC) patients diagnosed with severe radiation pneumonitis with secondary infections.Data...

Aug 23, 2021

Precision medicine risk stratification is desperately needed to both avoid systemic antifungals treatment delay and over prescription in the critically ill with risk factors. The aim of the present st...

Aug 23, 2021

To assess the prognostic utility of admission quick Sequential Organ Failure Assessment (qSOFA) scores for in-hospital mortality in a population of dogs with surgically treated sepsis.Retrospective co...

Aug 23, 2021

Coagulopathy is a well-recognized risk factor for poor outcomes in patients with traumatic brain injury (TBI). Differences in the time courses of coagulation and fibrinolytic parameters between pediat...

Aug 23, 2021

To determine the risk of mortality from mental disorders and suicide in professional sports associated with repeated head impacts.A systematic search was performed in PubMed, Web of Science, Scopus, a...

Aug 23, 2021

Repetitive transcranial magnetic stimulation (rTMS) is an FDA-approved therapy in major depressive disorder. However, its treatment efficacy on depression after traumatic brain injury (TBI) remains in...

Aug 23, 2021

Targeted therapies have transformed treatment of driver-mutated metastatic non-small cell lung carcinoma (NSCLC). We compared cardiovascular adverse events between and within targeted therapy classes....

Aug 23, 2021

Management of left ventricular assist device (LVAD)-associated intracranial hemorrhage (ICH) is complicated by the competing concerns of hematoma expansion and the risk of thrombosis. Strategies inclu...

Aug 23, 2021

Lactate is an established prognosticator in critical care. However, there still is insufficient evidence about its role in predicting outcome in COVID-19. This is of particular concern in older patien...

Aug 20, 2021

By Carolyn Crist Suicide is the only cause of death that is higher among doctors than the general population, according to two Canadian physicians who coauthored an information sheet about physicia...

Aug 19, 2021

Nrf2, the master gene transcriptor of antioxidant proteins, and SIRT1, the unique Class III histone deacetylase of sirtuins, have been involved in protecting myocardial ischemia/reperfusion (MI/R) inj...

Aug 19, 2021

About two-thirds of sudden deaths are sudden cardiac deaths (SCD), and ischemic heart disease (IHD) accounts for 60% of these. Although an autopsy needs to be performed to prove SCD, the forensic auto...