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Critical Care General

Targeted therapies of inflammatory diseases with intracellularly gelated macrophages in mice and rats.

Jan 08, 2024

Membrane-camouflaged nanomedicines often suffer from reduced efficacy caused by membrane protein disintegration and spatial disorder caused by separation and reassembly of membrane fragments during th...

Autoimmune encephalitis and paraneoplastic encephalitis: difficulties in diagnosis and management in the ICU.

Jan 08, 2024

Autoimmune encephalitis (AIE) represents a category of relatively newly described neurological disorders associated with an increasing prevalence, a significant impact on the healthcare system, and a ...

Outbreak of group B Streptococcus in a neonatal care unit confirmed by whole-genome sequencing.

Jan 08, 2024

Clusters of group B Streptococcus (GBS) infections in neonatal intensive care units (NICU) are poorly documented. We aimed to assess GBS cross-transmission during an outbreak of GBS sepsis.The study w...

Unveiling cytokine charge disparity as a potential mechanism for immune regulation.

Jan 08, 2024

Cytokines are small signaling proteins that regulate the immune responses to infection and tissue damage. Surface charges of cytokines determine their in vivo fate in immune regulation, e.g., half-lif...

Concomitant severe traumatic brain injury is not associated with increased red blood cell transfusion volumes in patients with pelvic fractures: A retrospective observational study.

Jan 08, 2024

Traumatic brain injury (TBI)-associated coagulopathy significantly influences survival outcomes in patients with multiple injuries. Severe TBI can potentially affect systemic hemostasis due to coagulo...

Optimizing cardiac amyloidosis assessment: utility of 1-h and 3-h Tc-PYP imaging.

Jan 08, 2024

Transthyretin amyloid cardiomyopathy (ATTR-CM), characterized by the extracellular deposition of an insoluble amyloid protein in the heart, is one of the main causes of heart failure in elderly patien...

Intra-aortic balloon pump still has a role in late-onset myocardial infarction complicated by ventricular septal rupture with intractable heart failure: a case report.

Jan 08, 2024

The current guidelines have discouraged the routine use of intra-aortic balloon pump (IABP) in cardiogenic shock complicating acute coronary syndrome (ACS). Since then, the trend of IABP utilization i...

[Therapeutic Plasma Exchange in a Patient with Chronic Hemodialysis and a New Diagnosis of Myasthenia Gravis].

Jan 01, 2024

C.S.T. (♂, 71 years old) is a patient with multiple and severe comorbidities, undergoing thrice-weekly chronic hemodialysis since 2008 due to the progression of post-lithiasic uropathy. Over the pas...

Patient predictors of pathogenic versus commensal Gram-positive bacilli organisms isolated from blood cultures.

Jan 01, 2024

Gram-positive bacilli represent a diverse species of bacteria that range from commensal flora to pathogens implicated in severe and life-threatening infection. Following the isolation of Gram-positive...

Subcortical functional connectivity and its association with walking performance following deployment related mild TBI.

Jan 01, 2024

The relation between traumatic brain injury (TBI), its acute and chronic symptoms, and the potential for remote neurodegenerative disease is a priority for military research. Structural and functional...

Machine learning-based model for predicting inpatient mortality in adults with traumatic brain injury: a systematic review and meta-analysis.

Jan 01, 2024

Predicting mortality from traumatic brain injury facilitates early data-driven treatment decisions. Machine learning has predicted mortality from traumatic brain injury in a growing number of studies,...

Arterial revascularization in patients with hand pain dialyzing with upper arm Arteriovenous (AV) fistulas: A single center experience.

Dec 25, 2023

Distal hand ischemia syndrome (DHIS) is a well reported adverse outcome in patients with upper arm AV access. 25%-40% of these patients have been reported to be due to primary arterial disease complic...

Plasma soluble suppression of tumorigenesis 2 measured in the emergency department for diagnosis and outcome prediction of sepsis: A single-center prospective study.

Dec 25, 2023

The diagnostic and prognostic performance of soluble Suppression of Tumorigenicity 2 (sST2) in suspected septic patients presenting to the Emergency Department (ED) is largely unknown.Patients were in...

Treatment Outcomes of Complement Protein C5 Inhibition in 509 UK Patients with Paroxysmal Nocturnal Hemoglobinuria.

Dec 25, 2023

Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired clonal hematopoietic disorder which occurs on a background of bone marrow failure (BMF). In PNH, chronic intravascular hemolysis causes an incr...

Timing and Morbidity of Intracranial Meningioma Resection Complications.

Dec 25, 2023

Intracranial meningioma resection is associated with multiple acute post-operative complications, including cerebrovascular accidents, surgical site infections, and pneumonia. There is a paucity of re...

Sepsis increases the risk of in-hospital cardiac arrest: a population-based analysis.

Dec 25, 2023

Sepsis patients have a high risk of developing in-hospital cardiac arrest (IHCA), which portends poor survival. However, little is known about whether the increased incidence of IHCA is due to sepsis ...

Infective endocarditis and septic arthritis caused by Corynebacteriumstriatum.

Dec 25, 2023

Corynebacterium striatum occasionally causes nosocomial infections, such as catheter-related bloodstream infection and pneumonia; however, C. striatum-related infective endocarditis or septic arthriti...

Assessing the Effects of Mild Traumatic Brain Injury on Vestibular Home Exercise Performance with Wearable Sensors.

Dec 25, 2023

After a mild traumatic brain injury (mTBI), dizziness and balance problems are frequently reported, affecting individuals' daily lives and functioning. Vestibular rehabilitation is a standard treatmen...

Clinical Practice Guideline Recommendations in Pediatric Mild Traumatic Brain Injury: A Systematic Review.

Dec 25, 2023

Our primary objectives were to identify clinical practice guideline recommendations for children with acute mild traumatic brain injury (mTBI) presenting to an emergency department (ED), appraise thei...

Pediatric Mechanical Circulatory Support: Introduction and Schneider's Experience.

Dec 25, 2023

Ventricular assist devices (VADs) play a critical and increasing role in treating end-stage heart failure in pediatric patients. A growing number of patients are supported by VADs as a bridge to heart...

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