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Critical Care General

Fructose-coated Ångstrom silver prevents sepsis by killing bacteria and attenuating bacterial toxin-induced injuries.

Aug 12, 2021

Serious infection caused by multi-drug-resistant bacteria is a major threat to human health. Bacteria can invade the host tissue and produce various toxins to damage or kill host cells, which may indu...

PCSK9 and inflammation. Maybe a role in autoimmune diseases? Focus on rheumatoid arthritis and systemic lupus erythematosus.

Aug 12, 2021

Despite a clear epidemiological link between autoimmune disease and cardiovascular (CV) risk exists, pathophysiological explanations are extremely complex and far from being elucidated. Dysregulation ...

High School Sports-related Concussion and the Effect of a Jugular Vein Compression Collar: A Prospective Longitudinal Investigation of Neuroimaging and Neurofunctional Outcomes.

Aug 12, 2021

Sports-related concussion (SRC) can exert serious acute and long-term consequences on brain microstructure, function, and behavioral outcomes. We aimed to quantify the alterations in white matter (WM)...

Interpreting Clinical Reaction Time Change and Recovery After Concussion: A Baseline Versus Norm-Based Cutoff Score Comparison.

Aug 12, 2021

Preseason testing can be time intensive and cost prohibitive. Therefore, using normative data for postconcussion interpretation in lieu of preseason testing is desirable.To establish the recovery traj...

Pathology of fatal diffuse brain injury in severe non-penetrating head trauma.

Aug 12, 2021

Traumatic brain injury (TBI) is recognised as a serious global public health problem that imposes a heavy socioeconomic burden on society. The vast majority of cases result from road traffic accidents...

Ischemic heart failure mortality is not predicted by cardiac insulin resistance but by diabetes perse and coronary flow reserve: A retrospective dynamic cardiac F-FDG PET study.

Aug 12, 2021

The connection between peripheral insulin resistance (IR) and coronary artery disease is well-established. Both are major risk factors for the development of ischemic cardiomyopathy potentially leadin...

Characteristics and outcomes of MitraClip in octogenarians: Evidence from 1853 patients in the GIOTTO registry.

Aug 12, 2021

We aimed at appraising features and outcomes of patients undergoing MitraClip treatment according to their age.We queried the prospective GIOTTO multicenter registry including 19 Italian centers perfo...

Adrenaline improves regional cerebral blood flow, cerebral oxygenation and cerebral metabolism during CPR in a porcine cardiac arrest model using low-flow extracorporeal support.

Aug 09, 2021

The effects of adrenaline on cerebral blood vessels during cardiopulmonary resuscitation (CPR) are not well understood. We developed an extracorporeal CPR model that maintains constant low systemic bl...

Timing of Anticoagulation after Stroke in Patients with Non-Valvular Atrial Fibrillation Assessment of Provider Practices.

Aug 09, 2021

Optimal timing of oral anticoagulation (TOAC) in acute ischemic stroke (AIS) in patients with atrial fibrillation (AF) is unknown. The risk of recurrent ischemic events when treatment is delayed is of...

Surgical management of chronic pulmonary aspergillosis in Africa: a systematic review of 891 cases.

Aug 09, 2021

Chronic pulmonary aspergillosis (CPA) is an emerging fungal infectious disease of public health importance. We conducted a systematic review of studies reporting the outcomes of patients with CPA mana...

Faecal sludge pyrolysis: Understanding the relationships between organic composition and thermal decomposition.

Aug 09, 2021

Sludge treatment is an integral part of faecal sludge management in non-sewered sanitation settings. Development of pyrolysis as a suitable sludge treatment method requires thorough knowledge about th...

Activation of CB2 receptor inhibits pyroptosis and subsequently ameliorates cecal ligation and puncture-induced sepsis.

Aug 09, 2021

Cannabinoid receptor 2 (CB2), whose activities are upregulated during sepsis, may be related to the regulation of inflammatory programmed cell death called pyroptosis. The aim of this study is to inve...

Pulmonary Pathology Diagnoses in the US Military During the Global War on Terrorism.

Aug 09, 2021

To document and compare prevalences of pulmonary pathology diagnoses among US Service members deployed during the Global War on Terrorism and non-deployed US service members. Difficulties establishing...

Homologous recombination as a mechanism of genetic changes in bovine parainfluenza-3 virus.

Aug 09, 2021

Bovine parainfluenza-3 virus (BPIV-3) is one of the main viruses associated with bovine respiratory disease complex (BRDC) worldwide. BPIV-3 infect the bovine respiratory tract causing from subclinica...

Systematic review and meta-analysis of chest radiograph (CXR) findings in COVID-19.

Aug 09, 2021

Chest radiography (CXR) is most likely to be the utilized modality for diagnosing COVID-19 and following up on any lung-associated abnormalities. This review provides a meta-analysis of the current li...

Milrinone as Compared with Dobutamine in the Treatment of Cardiogenic Shock.

Aug 09, 2021

Cardiogenic shock is associated with substantial morbidity and mortality. Although inotropic support is a mainstay of medical therapy for cardiogenic shock, little evidence exists to guide the selecti...

Clinical Outcome of Rotational Atherectomy in Calcified Lesions in Korea-ROCK Registry.

Aug 09, 2021

: Data is still limited regarding clinical outcomes of rotational atherectomy (RA) after percutaneous coronary intervention. We sought to evaluate clinical outcomes of RA. This multi-center registry ...

Risk factors profile of young and older patients with Myocardial Infarction.

Aug 09, 2021

Myocardial infarction (MI) among young adults (< 45 years) represents a considerable proportion of the total heart attack incidents. The underlying pathophysiologic characteristics, atherosclerotic...

A Novel Peptide Derived from the Transmembrane Domain of Romo1 Is a Promising Candidate for Sepsis Treatment and Multidrug-Resistant Bacteria.

Aug 09, 2021

The emergence of multidrug-resistant (MDR) bacteria through the abuse and long-term use of antibiotics is a serious health problem worldwide. Therefore, novel antimicrobial agents that can cure an inf...

Retrospective single-centre descriptive study of the characteristics, management and outcomes of adult patients with suspected sepsis in the emergency department.

Aug 09, 2021

Guidelines for adults presenting to the emergency department (ED) with suspected sepsis recommend protocols and bundles that promote rapid and potentially intensive treatment, but give little consider...

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