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Critical Care General

Characteristics and outcomes of MitraClip in octogenarians: Evidence from 1853 patients in the GIOTTO registry.

Aug 12, 2021

We aimed at appraising features and outcomes of patients undergoing MitraClip treatment according to their age.We queried the prospective GIOTTO multicenter registry including 19 Italian centers perfo...

Adrenaline improves regional cerebral blood flow, cerebral oxygenation and cerebral metabolism during CPR in a porcine cardiac arrest model using low-flow extracorporeal support.

Aug 09, 2021

The effects of adrenaline on cerebral blood vessels during cardiopulmonary resuscitation (CPR) are not well understood. We developed an extracorporeal CPR model that maintains constant low systemic bl...

Timing of Anticoagulation after Stroke in Patients with Non-Valvular Atrial Fibrillation Assessment of Provider Practices.

Aug 09, 2021

Optimal timing of oral anticoagulation (TOAC) in acute ischemic stroke (AIS) in patients with atrial fibrillation (AF) is unknown. The risk of recurrent ischemic events when treatment is delayed is of...

Surgical management of chronic pulmonary aspergillosis in Africa: a systematic review of 891 cases.

Aug 09, 2021

Chronic pulmonary aspergillosis (CPA) is an emerging fungal infectious disease of public health importance. We conducted a systematic review of studies reporting the outcomes of patients with CPA mana...

Faecal sludge pyrolysis: Understanding the relationships between organic composition and thermal decomposition.

Aug 09, 2021

Sludge treatment is an integral part of faecal sludge management in non-sewered sanitation settings. Development of pyrolysis as a suitable sludge treatment method requires thorough knowledge about th...

Activation of CB2 receptor inhibits pyroptosis and subsequently ameliorates cecal ligation and puncture-induced sepsis.

Aug 09, 2021

Cannabinoid receptor 2 (CB2), whose activities are upregulated during sepsis, may be related to the regulation of inflammatory programmed cell death called pyroptosis. The aim of this study is to inve...

Pulmonary Pathology Diagnoses in the US Military During the Global War on Terrorism.

Aug 09, 2021

To document and compare prevalences of pulmonary pathology diagnoses among US Service members deployed during the Global War on Terrorism and non-deployed US service members. Difficulties establishing...

Homologous recombination as a mechanism of genetic changes in bovine parainfluenza-3 virus.

Aug 09, 2021

Bovine parainfluenza-3 virus (BPIV-3) is one of the main viruses associated with bovine respiratory disease complex (BRDC) worldwide. BPIV-3 infect the bovine respiratory tract causing from subclinica...

Systematic review and meta-analysis of chest radiograph (CXR) findings in COVID-19.

Aug 09, 2021

Chest radiography (CXR) is most likely to be the utilized modality for diagnosing COVID-19 and following up on any lung-associated abnormalities. This review provides a meta-analysis of the current li...

Milrinone as Compared with Dobutamine in the Treatment of Cardiogenic Shock.

Aug 09, 2021

Cardiogenic shock is associated with substantial morbidity and mortality. Although inotropic support is a mainstay of medical therapy for cardiogenic shock, little evidence exists to guide the selecti...

Clinical Outcome of Rotational Atherectomy in Calcified Lesions in Korea-ROCK Registry.

Aug 09, 2021

: Data is still limited regarding clinical outcomes of rotational atherectomy (RA) after percutaneous coronary intervention. We sought to evaluate clinical outcomes of RA. This multi-center registry ...

Risk factors profile of young and older patients with Myocardial Infarction.

Aug 09, 2021

Myocardial infarction (MI) among young adults (< 45 years) represents a considerable proportion of the total heart attack incidents. The underlying pathophysiologic characteristics, atherosclerotic...

A Novel Peptide Derived from the Transmembrane Domain of Romo1 Is a Promising Candidate for Sepsis Treatment and Multidrug-Resistant Bacteria.

Aug 09, 2021

The emergence of multidrug-resistant (MDR) bacteria through the abuse and long-term use of antibiotics is a serious health problem worldwide. Therefore, novel antimicrobial agents that can cure an inf...

Retrospective single-centre descriptive study of the characteristics, management and outcomes of adult patients with suspected sepsis in the emergency department.

Aug 09, 2021

Guidelines for adults presenting to the emergency department (ED) with suspected sepsis recommend protocols and bundles that promote rapid and potentially intensive treatment, but give little consider...

Combined procalcitonin and hemogram parameters contribute to early differential diagnosis of Gram-negative/Gram-positive bloodstream infections.

Aug 09, 2021

Hemogram parameters and procalcitonin (PCT) play auxiliary roles in the diagnosis and outcome of sepsis. However, it is not clear whether these indicators can quickly distinguish bacterial classificat...

Investigation of the direct and indirect mechanisms of primary blast insult to the brain.

Aug 09, 2021

The interaction of explosion-induced blast waves with the head (i.e., a direct mechanism) or with the torso (i.e., an indirect mechanism) presumably causes traumatic brain injury. However, the underst...

Studying professional and recreational female footballers: A bibliometric exercise.

Aug 09, 2021

Research directed at soccer has seen dramatic growth in the last decade. While published research on soccer has shown exponential growth, the proportion of articles addressing females is lagging behin...

Vestibular-Evoked Myogenic Potential Outcomes Associated with Pediatric Sports-Related Concussion.

Aug 09, 2021

To 1) characterize vestibular-evoked myogenic potential responses in children and young adults with sports-related concussion (SRC) histories as compared with a normal healthy control group, and 2) co...

The UpPriority tool supported prioritization processes for updating clinical guideline questions.

Aug 09, 2021

We aim to 1) use the UpPriority tool to identify which clinical questions (CQs) within the clinical guidelines (CGs) need to be prioritized for updating and 2) assess the implementation of the tool in...

2021 PACES Expert Consensus Statement on the Indications and Management of Cardiovascular Implantable Electronic Devices in Pediatric Patients.

Aug 09, 2021

In view of the increasing complexity of both cardiovascular implantable electronic devices (CIEDs) and patients in the current era, practice guidelines, by necessity, have become increasingly specific...

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