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Critical Care General

GCS-Pupil Score Has a Stronger Association with Mortality and Poor Functional Outcome than GCS Alone in Pediatric Severe Traumatic Brain Injury.

Jul 22, 2021

The Glasgow Coma Scale (GCS), used to classify the severity of traumatic brain injury (TBI), is associated with mortality and functional outcomes. However, GCS can be affected by sedation and neuromus...

Gangliosides combined with mild hypothermia provides neuroprotection in a rat model of traumatic brain injury.

Jul 22, 2021

Traumatic brain injury (TBI) remains a major cause of disability and death in modern society. In this study, we explored the neuroprotection role of the combination of gangliosides (GM) and mild hypot...

Assessment of the Effect of Amantadine in Patients with Traumatic Brain Injury: A Meta-Analysis.

Jul 22, 2021

Traumatic brain injury is a global burden. We aimed to perform a meta-analysis to determine the efficacy of amantadine for cognitive performance after traumatic brain injury.The systematic review was ...

A follow-up study of patients with COVID-19 presenting with seizures.

Jul 19, 2021

We performed a follow-up study of patients with COVID-19 presenting with seizures.All consecutive patients with seizures, who were referred to Namazee Hospital, Shiraz, Iran, with a diagnosis of COVID...

The Effect of Ceruloplasmin Against Ischemia-Reperfusion Injury in Epigastric Island Flap in Rats.

Jul 19, 2021

Flap surgery is frequently used in plastic surgery to close tissue defects. Ischemia-reperfusion (I/R) injury is a significant problem resulting in partial or total flap necrosis. This study aimed to ...

Genomic analysis of a multidrug-resistant Brucella anthropi strain isolated from a 4-day old neonatal sepsis patient.

Jul 19, 2021

Brucella anthropi is a gram negative, aerobic, motile, oxidase-positive, non-fermentative alphaproteobacteria belonging to the family Brucellaceae. It is most commonly found in the soil but is an emer...

Standardized treatment protocol for necrotizing otitis externa: retrospective case series and systematic literature review.

Jul 19, 2021

In the literature, there is no consensus on the most effective treatment protocol for Necrotising otitis externa (NOE). This article aims to produce a NOE treatment protocol from literature and clinic...

A quality improvement project to reduce antibiotic utilization and ancillary laboratory tests in the appraisal of early-onset sepsis in the NICU.

Jul 19, 2021

Diagnosis and treatment of early-onset sepsis (EOS) of the newborn remains a controversial issue among providers due to the non-infectious symptomology which exists in the newborn period.Pre/post inte...

Cause-of-death trends among adults with and without cerebral palsy in the United States, 2013-2017.

Jul 19, 2021

Adults with cerebral palsy (CP) in the United States die much earlier than those without CP, a health inequality likely shaped by causes of death. Existing research has not considered demographic diff...

Bayesian convolutional neural network estimation for pediatric pneumonia detection and diagnosis.

Jul 19, 2021

Pneumonia is a disease that affects the lungs, making breathing difficult. Nowadays, pneumonia is the disease that kills the most children under the age of five in the world, and if no action is taken...

The impact of COVID-19 on nursing workload and planning of nursing staff on the Intensive Care: A prospective descriptive multicenter study.

Jul 19, 2021

The impact of the care for COVID-19 patients on nursing workload and planning nursing staff on the Intensive Care Unit has been huge. Nurses were confronted with a high workload and an increase in the...

MI-PACE Home-Based Cardiac Telerehabilitation Program for Heart Attack Survivors: Usability Study.

Jul 19, 2021

Cardiac rehabilitation programs, consisting of exercise training and disease management interventions, reduce morbidity and mortality after acute myocardial infarction.In this pilot study, we aimed to...

The circulatory small non-coding RNA landscape in community-acquired pneumonia on intensive care unit admission.

Jul 19, 2021

Community-acquired pneumonia (CAP) is a major cause of sepsis. Despite several clinical trials targeting components of the inflammatory response, no specific treatment other than antimicrobial therapy...

The impact of acute pneumococcal disease on health state utility values: a systematic review.

Jul 19, 2021

Streptococcus pneumoniae infections remain a significant source of morbidity and mortality worldwide. The purpose of this review was to summarize the impact of pneumococcal disease on health state uti...

Availability of facility resources and services and infection-related maternal outcomes in the WHO Global Maternal Sepsis Study: a cross-sectional study.

Jul 19, 2021

Infections are among the leading causes of maternal mortality and morbidity. The Global Maternal Sepsis and Neonatal Initiative, launched in 2016 by WHO and partners, sought to reduce the burden of ma...

Engraftment of double cord blood transplantation after non-myeloablative conditioning with escalated total body irradiation dosing to facilitate engraftment in immunocompetent patients.

Jul 19, 2021

In order to improve accrual to a randomized clinical trial of double unrelated cord blood (dUCB) versus HLA-haploidentical bone marrow (Haplo-BM) transplantation, patients with less prior therapy and ...

Condition-specific health-related quality of life amongst amateur athletes six months and one-year following sport-related concussion: A prospective, follow-up.

Jul 19, 2021

To prospectively investigate the condition-specific health-related quality of life (HRQoL) of athletes six months and one-year following sport-related concussion.Prospective, longitudinal study.Clinic...

Ability of neutrophil-to-lymphocyte ratio to predict secondary neurological impairment in patients with mild to moderate head injury. A retrospective study.

Jul 19, 2021

The main objective was to assess the performance of the neutrophil-lymphocyte ratio (NLR) for early prediction of delayed neurological impairment and cerebral contusion worsening in patients with mild...

Right Heart Dysfunction and Readmission Risk across Left Ventricular Ejection Fraction Status in Patients with Acute Heart Failure.

Jul 19, 2021

Right heart dysfunction (RHD) parameters are increasingly important in heart failure (HF). This study aimed to evaluate the association of advanced RHD with the risk of recurrent admissions across the...

Cardiac Pathology in COVID-19: A Single Center Autopsy Experience.

Jul 19, 2021

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is commonly associated with myocardial injury and heart failure. The pathophysiology behind this phenomenon remains unclear, with many dive...

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