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Critical Care General

Epidemiology of child playground equipment-related injuries in the USA: Emergency department visits, 1995-2019.

Jul 12, 2021

To analyse the most recent trends and characteristics of playground equipment-related injuries in children.We used the National Electronic Injury Surveillance System database to acquire cases of playg...

Development and External Validation of the KIIDS-TBI Tool for Managing Children with Mild Traumatic Brain Injury and Intracranial Injuries.

Jul 12, 2021

Clinical decision support may improve the post-neuroimaging management of children with mild traumatic brain injuries (mTBI) and intracranial injuries. While the CHIIDA score has been proposed for thi...

Dilated cardiomyopathy: a new insight into the rare but common cause of heart failure.

Jul 12, 2021

Heart failure is a global health burden responsible for high morbidity and mortality with a prevalence of greater than 60 million individuals worldwide. One of the major causes of heart failure is dil...

Long non-coding RNA Pvt1 modulates the pathological cardiac hypertrophy via miR-196b-mediated OSMR regulation.

Jul 12, 2021

Cardiac hypertrophy is the uppermost risk factor for the development of heart failure, leading to irreversible cardiac structural remodeling and sudden death. As a major mediator of cardiac remodeling...

Stump appendicitis after laparoscopic appendectomy; laparoscopic management and literature review.

Jul 08, 2021

Appendectomy is one of the most common surgical procedures performed worldwide There are different etiologies for acute appendicitis such as obstruction of the appendiceal lumen by fecalith, lymphoid ...

Use of graft-derived cell-free DNA as a novel biomarker to predict allograft function after kidney transplantation.

Jul 08, 2021

To investigate the association between graft-derived cell-free DNA and pretransplantation clinical variables, and to determine whether the former could be used as a novel biomarker to predict renal fu...

New insights into lipopolysaccharide inactivation mechanisms in sepsis.

Jul 08, 2021

The complex pathophysiology of sepsis makes it a syndrome with limited therapeutic options and a high mortality rate. Gram-negative bacteria containing lipopolysaccharides (LPS) in their outer membran...

Effects of different lipid emulsions on serum adipokines, inflammatory markers and mortality in critically ill patients with sepsis: A prospective observational cohort study.

Jul 08, 2021

Intravenous lipid emulsions in parenteral nutrition may cause different metabolic responses and immune effects in critically ill patients with sepsis. The aim of this study is to investigate the effec...

Home parenteral nutrition patients on mixed oil lipid emulsion have a higher rate of hospitalizations compare to those on soybean oil- a prospective 2-year cohort study.

Jul 08, 2021

Mixed oil intravenous lipid emulsion (MO ILE) that contains 30% soybean oil (SO), 30% medium chain triglycerides, 25% olive oil and 15% fish oil can benefit hospitalized patients receiving parenteral ...

Antimicrobial coating prevents ventilator-associated pneumonia in a 72 hour large animal model.

Jul 08, 2021

The primary goal of this study was to demonstrate that endotracheal tubes coated with antimicrobial lipids plus mucolytic or antimicrobial lipids with antibiotics plus mucolytic would significantly re...

Choquet fuzzy integral-based classifier ensemble technique for COVID-19 detection.

Jul 08, 2021

The COVID-19 outbreak has resulted in a global pandemic and led to more than a million deaths to date. COVID-19 early detection is essential for its mitigation by controlling its spread from infected ...

N-acylhydrazones confer inhibitory efficacy against New Delhi metallo-β-lactamase-1.

Jul 08, 2021

The expression of β-lactamases, especially metallo-β-lactamases (MβLs) in bacteria is one of the main causes of drug resistance. In this work, an effective N-acylhydrazone scaffold as MβL inhibito...

Isolated renal mucormycosis presenting with bilateral renal artery thrombosis: a case report.

Jul 08, 2021

Mucormycosis is a rare infection caused by the fungus belonging to the order . Mucormycosis predominantly affects immunocompromised individuals such as people with acquired immunodeficiency syndrome, ...

Total hip arthroplasty for failed acetabular fracture: a double-center comparative study on failed proximal femur fracture.

Jul 08, 2021

This study aimed to compare the clinical and radiological outcomes of patients who underwent total hip arthroplasty (THA) after failed osteosynthesis of acetabular fractures vs. fractures of the proxi...

Method development and characterisation of the low-molecular-weight peptidome of human wound fluids.

Jul 08, 2021

The normal wound healing process is characterised by proteolytic events, whereas infection results in dysfunctional activations by endogenous and bacterial proteases. Peptides, downstream reporters of...

Minor Traumatic Intracranial Hemorrhage: Identifying Prognostic Factors and Comparing Patients With Favorable and Unfavorable Outcomes.

Jul 08, 2021

Whether patients with minor traumatic intracranial hemorrhage (MTICH) require intensive care remains uncertain. This study aimed to identify the factors affecting the postinjury neurological outcomes ...

Current status of websites offering information to traumatic brain injury patients and caregivers: time for reform?

Jul 08, 2021

Traumatic brain injury (TBI) is a global public health problem, causing long-term burden to patients and caregivers. Patients and their families often resort to seeking online information regarding TB...

The detection of mild traumatic brain injury in paediatrics using artificial neural networks.

Jul 08, 2021

Head computed tomography (CT) is the gold standard in emergency departments (EDs) to evaluate mild traumatic brain injury (mTBI) patients, especially for paediatrics. Data-driven models for successful...

Comorbidities, sequelae, blood biomarkers and their associated clinical outcomes in the Mount Sinai Health System COVID-19 patients.

Jul 08, 2021

With the continuing rise of SARS-CoV2 infection globally and the emergence of various waves in different countries, understanding characteristics of susceptibility to infection, clinical severity, and...

Age and clinical outcomes after hip fracture surgery: do octogenarian, nonagenarian and centenarian classifications matter?

Jul 08, 2021

older patients with hip fractures are arbitrarily classified as octogenarians, nonagenarians and centenarians. We have designed this study to quantify in-hospital mortality and complications among eac...

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