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Critical Care General

Appropriateness of empirical antibiotic therapy and added value of adjunctive gentamicin in patients with septic shock: a prospective cohort study in the ICU.

Jun 24, 2021

To determine the appropriateness of empiric antibiotic therapy and the possible benefit of adding short-course gentamicin in septic shock patients with abdominal, urogenital, or an unknown focus. Seco...

Long-term Outcomes after Seton Placement for Perianal Fistulae with and without Crohn's Disease.

Jun 24, 2021

Perianal sepsis in Crohn's fistulae is managed with antibiotics and surgical drainage; a non-cutting seton is used for an identified trans-sphincteric fistula tract. Optimal management following seton...

Sensitivity and specificity of the INECO frontal screening (IFS) in the detection of patients with traumatic brain injury presenting executive deficits.

Jun 24, 2021

Executive dysfunction (EF) is a common feature of adult traumatic brain injury (TBI), especially in moderate to severe cases. Assessing EF usually requires the administration of an extensive neuropsyc...

A meta-analysis of cohort studies: Traumatic brain injury and risk of Alzheimer's Disease.

Jun 24, 2021

Recently, some epidemiological studies have reported that cognitive disorders in elderly people is accelerated with traumatic brain injury. But the causal relationship between traumatic brain injury a...

The timeframe for safe resumption of high-level mobility following traumatic brain injury is currently unknown: a systematic review.

Jun 24, 2021

To examine the safety of high-level mobility (HLM) prescription in the early sub-acute phase of recovery following moderate-to-extremely severe traumatic brain injury (TBI) with specific focus on prov...

Statin associated lower cancer risk and related mortality in patients with heart failure.

Jun 24, 2021

Patients with heart failure (HF) have an increased risk of incident cancer. Data relating to the association of statin use with cancer risk and cancer-related mortality among patients with HF are spar...

[Reversible left ventricular hypertrophy and congestive heart failure due to suspected myocarditis in a cat in the course of FLUTD].

Jun 24, 2021

A 2.5-year-old castrated male domestic shorthair cat with a past pertinent history of FLUTD treatment 8 days earlier was presented during the night due to apathy and anorexia. Radiographs, ECG, bloo...

Practice, Outcomes and Complications of Emergent Endotracheal Intubation By Critical Care Practitioners During the COVID-19 Pandemic.

Jun 24, 2021

For patients with novel coronavirus 2019 (COVID-19) who undergo emergency endotracheal intubation, there is limited data regarding the practice, outcomes and complications of this procedure.For COVID-...

Baseline Frailty as a Predictor of Survival after Critical Care: a Retrospective Cohort Study of Older Adults Receiving Home Care in Ontario, Canada.

Jun 24, 2021

The extent by which the degree of baseline frailty, as measured using standardized multidimensional health assessments before admission to hospital, predicts survival among older adults following admi...

Multimorbidity and its relationship with long-term outcomes following critical care discharge: a prospective cohort study.

Jun 24, 2021

Survivors of critical illness have poor long-term outcomes with subsequent increases in healthcare utilisation. Less is known about the interplay between multimorbidity and long-term outcomes.How do b...

Symptoms of Mental Health Disorders in Critical Care Physicians Facing the Second COVID-19 Wave: A Cross-Sectional Study.

Jun 21, 2021

Working in the ICU during the first COVID-19 wave was associated with high levels of mental health disorders.What are the mental health symptoms in health-care providers (HCPs) facing the second wave?...

Exploring Healthcare Super-Utilization in Gynecologic Oncology

Jun 18, 2021

Unplanned acute care continues to be a major contributor to growing healthcare costs in the United States, especially among patients with cancer. Quality measures have been developed to reduce healthc...

Strict Rest May Slow Recovery From Sports-Related Concussion

Jun 17, 2021

WEDNESDAY, June 16, 2021 (HealthDay News) -- Strict rest may slow recovery and prolong symptoms after sports-related concussion (SRC), according to a consensus statement published online June 15 in th...

Indoleamine-2,3-Dioxygenase Activates Wnt/β-Catenin Inducing Kidney Fibrosis after Acute Kidney Injury.

Jun 17, 2021

As disorder of tryptophan metabolism is common in CKD, the rate-limiting enzyme of tryptophan, indoleamine-2,3-dioxygenase (IDO), has been reported to be involved in CKD, while the accurate mechanism ...

Fatal necrotizing fasciitis in illegal abortion and the negligence tort.

Jun 17, 2021

The present paper is a case-based review on rare complications of illegal abortion, i.e., necrotizing fasciitis missed early by the treating gynecologists which landed up into a negligence tort agains...

Stimulus-Induced Rhythmic or Periodic Intermittent Discharges (SIRPIDs) in patients with triphasic waves and Creutzfeldt-Jakob disease.

Jun 17, 2021

Since the term Stimulus-Induced Rhythmic, Periodic, or Ictal Discharges (SIRPIDs) was introduced into the vocabulary of electrophysiologists/neurologists, there has been an ongoing debate about its si...

Rotational Thromboelastometry in Neonates Admitted to a Neonatal Intensive Care Unit: A Large Cross-sectional Study.

Jun 17, 2021

The aim of the present study was to assess the coagulation profile in neonatal critical illness using rotational thromboelastometry (ROTEM), and to investigate its association with disease severity an...

Clinical characteristics and outcomes of community-acquired pneumonia in western Saudi Arabia: A four-year retrospective analysis of medical records.

Jun 17, 2021

Community-acquired pneumonia (CAP) is a significant cause of morbidity and mortality, especially for the elderly and people who suffer from chronic conditions. This study was conducted to assess the c...

Anti-flagellin IgY antibodies protect against Pseudomonas aeruginosa infection in both acute pneumonia and burn wound murine models in a non-type-specific mode.

Jun 17, 2021

Pseudomonas aeruginosa (PA) is one of the most dominant causes of nosocomial infections in burn patients. Increasing emergence of antibiotic-resistant strains highlights the need for novel antimicrobi...

Early lung ultrasound assessment for the prognosis of patients hospitalized for COVID-19 pneumonia. A pilot study.

Jun 17, 2021

SARS CoV-2 is an epidemic viral infection that can cause mild to severe lung involvement. Newly apprehended knowledge on thoracic imaging abnormalities and the growing clinical experience on the evolu...

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