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Critical Care General

Measured energy expenditure in mildly hypothermic critically ill patients with traumatic brain injury: A sub-study of a randomized controlled trial.

Jun 17, 2021

Prophylactic hypothermia, often used in critically ill patients with traumatic brain injury, reduces energy expenditure and may affect energy delivered by nutrition therapy. The primary objective of t...

Early Goal-Directed Renal Replacement Therapy in Acute Decompensated Heart Failure Patients with Cardiorenal Syndrome.

Jun 17, 2021

The aim of this study was to clarify the efficacy of early goal-directed renal replacement therapy (GDRRT) for treatment of cardiorenal syndrome (CRS) patients after acute decompensated heart failure ...

Association of Acute Kidney Injury with Outcomes in Patients Undergoing Transcatheter Mitral Valve Repair.

Jun 17, 2021

Although transcatheter mitral valve repair (TMVr) is a contrast-free procedure, prior single-center studies have demonstrated a high incidence of acute kidney injury (AKI) following TMVr. The main obj...

Bronchoscopy teaching without a gold standard: attending pulmonologists' assessment of learners, supervisory styles, and variation in practice.

Jun 17, 2021

Despite the growing role of simulation in procedural teaching, bronchoscopy training is largely experiential and occurs during patient care. The Accreditation Council for Graduate Medical Education (A...

Intravenous Smart Pumps: Safety & Usability During Secondary Medication Administration

Jun 14, 2021

“Large-volume IV smart pumps are probably one of the most ubiquitous devices in acute care in the United States,” explains Karen K. Giuliano, PhD, MBA, RN, FAAN. “Unfortunately, the most commonl...

Glucose metabolic crosstalk and regulation in brain function and diseases.

Jun 14, 2021

Brain glucose metabolism, including glycolysis, the pentose phosphate pathway, and glycogen turnover, produces ATP for energetic support and provides the precursors for the synthesis of biological mac...

Sildenafil in endotoxin-induced pulmonary hypertension: an experimental study.

Jun 14, 2021

Sepsis and septic shock still represent great challenges in critical care medicine. Sildenafil has been largely used in the treatment of pulmonary arterial hypertension, but its effects in sepsis are ...

Effect of thiamine supplementation in critically ill patients: A systematic review and meta-analysis.

Jun 14, 2021

Several studies have previously shown the benefit of thiamine supplementation in critically ill patients. In order to fully appraise the available data, we performed a meta-analysis of 18 published st...

Fibrosing interstitial lung disease in primary Sjogren syndrome.

Jun 14, 2021

Interstitial lung disease (ILD) represents the main pulmonary involvement in primary Sjogren syndrome (pSS). A proportion of patients with pSS develop a progressive fibrosing form of ILD, but no data ...

COVID-19 prevalence forecasting using Autoregressive Integrated Moving Average (ARIMA) and Artificial Neural Networks (ANN): Case of Turkey.

Jun 14, 2021

A local outbreak of unknown pneumonia was detected in Wuhan (Hubei, China) in December 2019. It is determined to be caused by a severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) and called ...

Infections and patterns of antibiotic utilization in support and comfort care patients: A tertiary care center experience.

Jun 14, 2021

Little is known regarding the burden of infections and clinical practice towards hospitalized patients with limits on life-sustaining measures. We aim to describe the infectious syndromes, clinical ca...

Postoperative low molecular weight heparin bridging treatment for patients at high risk of arterial thromboembolism (PERIOP2): double blind randomised controlled trial.

Jun 14, 2021

To determine the efficacy and safety of dalteparin postoperative bridging treatment versus placebo for patients with atrial fibrillation or mechanical heart valves when warfarin is temporarily interru...

Interaction between thrombin potential and age on early clinical outcome in patients hospitalized for COVID-19.

Jun 14, 2021

Patients with Coronavirus Disease-2019 (COVID-19) have haemostatic dysfunction and are at higher risk of thrombotic complications. Although age is a major risk factor for outcome impairment in COVID-1...

Real-world safety and effectiveness of rivaroxaban using Japan-specific dosage during long-term follow-up in patients with atrial fibrillation: XAPASS.

Jun 14, 2021

The Xarelto Post-Authorization Safety and Effectiveness Study in Japanese Patients with Atrial Fibrillation (XAPASS) was designed to investigate safety and effectiveness during long-term follow-up of ...

High pyocyanin production and non-motility of Pseudomonas aeruginosa isolates are correlated with septic shock or death in bacteremic patients.

Jun 14, 2021

Studies of the outcome of Pseudomonas aeruginosa bacteremia (Pab) have focused mainly on antibiotic appropriateness. However, P. aeruginosa possesses many virulence factors whose roles in outcomes hav...

An overview on the COVID-19 complications in pediatric population: A pandemic dilemma.

Jun 14, 2021

The primary objective of this article is to understand the various complications caused by the coronavirus in the pediatric population.An electronic search was conducted using PubMed and incorporated ...

Arteriovenous Access Type and Risk of Mortality, Hospitalization, and Sepsis Among Elderly Hemodialysis Patients: A Target Trial Emulation Approach.

Jun 14, 2021

Evidence is mixed regarding the optimal choice of the first permanent vascular access for elderly patients on hemodialysis (HD). Lacking data from randomized controlled trials (RCT), we used a target ...

Neurogenesis in the adult Drosophila brain.

Jun 14, 2021

Neurodegenerative diseases such as Alzheimer's and Parkinson's currently affect ∼25 million people worldwide (Erkkinen et al. 2018). The global incidence of traumatic brain injury (TBI) is estimated...

The Impact of Combat Ocular Trauma and Traumatic Brain Injury on Vision- and Health-Related Quality of Life Among U.S. Military Casualties.

Jun 14, 2021

The purpose of this study was to assess visual and health-related quality of life (QOL) among U.S. military service members who sustained combat ocular trauma (COT) with or without associated traumati...

Clinical predictors of poor 30-day headache outcomes after an emergency department visit for acute post-traumatic headache.

Jun 14, 2021

We investigated clinical risk factors that predict poor 30-day headache outcomes among patients evaluated in the emergency department (ED) for post-traumatic headache (PTH).This was an analysis of dat...

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