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Critical Care General

Impact of recombinant human brain natriuretic peptide on emergency dialysis and prognosis in end-stage renal disease patients with type 4 cardiorenal syndrome.

Nov 27, 2023

Recombinant human brain natriuretic peptide (rhBNP) effects on type 4 cardiorenal syndrome (CRS) and adverse events such as heart failure rehospitalization and all-cause mortality have not been assess...

Neurovascular Correlates of Cobalamin, Folate, and Homocysteine in Dementia.

Nov 20, 2023

Cobalamin (Cbl) and folate are common supplements clinicians prescribe as an adjuvant therapy for dementia patients, on the presumption of their neurotrophic and/or homocysteine (Hcy) lowering effect....

Impact of emergency medicine clinical pharmacist practitioner-driven sepsis antibiotic interventions.

Nov 20, 2023

The 2021 Surviving Sepsis Campaign Guidelines recommend administration of antimicrobials within the first hour of recognition of sepsis. Over the last decade, several studies have demonstrated improve...

Age-different BMSCs-derived exosomes accelerate tendon-bone interface healing in rotator cuff tears model.

Nov 20, 2023

Rotator cuff tears (RCTs) are culprit of shoulder pain and dysfunction. Tendon-bone interface (TBI) mal-healing is an essential contributor to retear after RCTs. Consequently, present project was cond...

Admission S100B fails as neuro-marker but is a good predictor for intrahospital mortality in major trauma patients.

Nov 20, 2023

S100 B is an extensively studied neuro-trauma marker, but its specificity and subsequently interpretation in major trauma patients might be limited, since extracerebral injuries are known to increase ...

Screening UFMylation-associated genes in heart tissues of Ufm1-transgenic mice.

Nov 20, 2023

UFMylation is a ubiquitination-like modification that is related to endoplasmic reticulum stress and unfolded protein response. A recent study reported that Ufl1, a key enzyme of UFMylation, protects ...

The neutrophil percentage-to-albumin ratio is associated with all-cause mortality in patients with chronic heart failure.

Nov 20, 2023

In this study, we evaluated the predictive utility of neutrophil percentage-to-albumin ratio (NPAR) for all-cause mortality in patients with chronic heart failure (CHF).Patients diagnosed as CHF enrol...

Variable Practice, Variable Results: Impact of Post-Interview Communication Practices Among CCM/PCCM Fellowship Applicants and Program Directors.

Nov 20, 2023

While post-interview communication (PIC) guidelines exist, adherence is voluntary. There are no studies of PIC practices in Critical Care Medicine (CCM) and Pulmonary and Critical Care Medicine (PCCM)...

Cardiovascular Hospitalizations and Mortality Among Adults Aged 25 to 64 years in the United States.

Nov 13, 2023

Declines in cardiovascular mortality have stagnated in the United States since 2011. There is growing concern that these patterns reflect worsening cardiovascular health in younger adults. However, li...

High risk and low prevalence diseases: Infected urolithiasis.

Nov 13, 2023

Infected urolithiasis is a serious condition that carries with it a high rate of morbidity and mortality.This review highlights the pearls and pitfalls of infected urolithiasis, including presentation...

Weight-drop model as a valuable tool to study potential neurobiological processes underlying behavioral and cognitive changes secondary to mild traumatic brain injury.

Nov 13, 2023

The pathophysiology of post-traumatic brain injury (TBI) behavioral and cognitive changes is not fully understood, especially in its mild presentation. We designed a weight drop TBI model in mice to i...

Optic nerve sheath diameter sonography for the diagnosis of intracranial hypertension in Traumatic brain injury: A systematic review and meta-analysis.

Nov 13, 2023

Timely diagnosis and management of elevated intracranial pressure (ICP) in patients with traumatic brain injury (TBI) can significantly reduce mortality rates. Ultrasound examination of the optic nerv...

Clonal haematopoiesis of indeterminate potential predicts incident cardiac arrhythmias.

Nov 13, 2023

Clonal haematopoiesis of indeterminate potential (CHIP), the age-related expansion of blood cells with preleukemic mutations, is associated with atherosclerotic cardiovascular disease and heart failur...

Prediction of pulmonary aspergillosis in patients with ventilator-associated pneumonia.

Nov 13, 2023

Predictors of ICU-acquired pulmonary aspergillosis (IPA) are not well-established in critically ill patients with ventilator-associated pneumonia (VAP), making IPA commonly misdiagnosed and anti-funga...

Biopsychosocial factors of quality of life in individuals with moderate to severe traumatic brain injury: a scoping review.

Nov 06, 2023

Individuals with moderate to severe traumatic brain injury (TBI) experience changes in their quality-of-life (QOL) post-injury. Given the vast literature that exists about QOL after TBI, a scoping rev...

An image-driven micromechanical approach to characterize multiscale remodeling in infarcted myocardium.

Nov 06, 2023

Myocardial infarction (MI) is accompanied by the formation of a fibrotic scar in the left ventricle (LV) and initiates significant alterations in the architecture and constituents of the LV free wall ...

Stair climbing and the incidence of atherosclerotic cardiovascular disease: a population-based prospective cohort study.

Oct 30, 2023

Stair climbing is a readily available form of physical activity with potential cardioprotective merits. Herein, we investigated the association between stair climbing and atherosclerotic cardiovascula...

[Pathological features and diagnostic significance of lung biopsy in occupational lung diseases].

Oct 30, 2023

To investigate the clinicopathological characteristics of occupational lung diseases, to reduce the missed diagnoses and misdiagnoses of the diseases and to help standardize the diagnosis and treatme...

Contemporary Outcomes of Endovascular and Open Surgical Repair for Mycotic Aortic Aneurysms: A Systematic Review.

Oct 30, 2023

To perform a systematic review on contemporary outcomes of endovascular repair and open surgical repair (OSR) for the treatment of mycotic aortic aneurysm (MAA).A comprehensive literature search on th...

Efficacy of IVIG therapy for patients with sepsis: a systematic review and meta-analysis.

Oct 30, 2023

Sepsis is an overwhelming reaction to infection that comes with high morbidity and mortality. It requires urgent interventions in order to improve outcomes. Intravenous immunoglobulins (IVIG) are cons...

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