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Critical Care General

Nasopharyngeal Pneumococcal Colonization Density is Associated with Severe Pneumonia in Young Children in the Lao PDR.

May 13, 2021

No studies have explored the association between pneumococcal nasopharyngeal density and severe pneumonia using the WHO 2013 definition. In Lao People's Democratic Republic (Lao PDR), we determine the...

Coronary plaque composition influences biomechanical stress and predicts plaque rupture in a morpho-mechanic OCT analysis.

May 13, 2021

Plaque rupture occurs if stress within coronary lesions exceeds the protection exerted by the fibrous cap overlying the necrotic lipid core. However, very little is known about the biomechanical stres...

Macrophage-preferable delivery of the leucine-rich repeat domain of NLRX1 ameliorates lethal sepsis by regulating NF-κB and inflammasome signaling activation.

May 13, 2021

Sepsis is an acute systemic inflammatory disease triggered by bacterial infection leading organ dysfunctions that macrophages are responsible for major triggering of systemic inflammation. Treatment o...

Amikacin Combined with Fosfomycin for Treatment of Neonatal Sepsis in the Setting of Highly Prevalent Antimicrobial Resistance.

May 13, 2021

Antimicrobial resistance (particularly by extended spectrum β-lactamase and aminoglycoside modifying enzyme production) in neonatal sepsis is a global problem, particularly in low- and middle-income ...

Infantile orbital abscess: clinical presentation, microbiological profile, and management outcomes.

May 13, 2021

: Orbital abscesses in children are not uncommon. Unless managed in a timely fashion, they can potentially lead to vision-threatening as well as life-threatening complications. The objective of this s...

The utility of decompressive craniectomy in severe traumatic brain injury in Saudi Arabia trauma centers.

May 13, 2021

: Decompressive craniectomy (DC) represents an effective method for intracranial pressure (ICP) reduction in cases of severe traumatic brain injury (TBI). However, little is known regarding the attitu...

Noise Outcomes in Servicemembers Epidemiology (NOISE) Study: Design, Methods, and Baseline Results.

May 13, 2021

Military Service members and Veterans commonly report hearing loss and tinnitus, both of which can result in significant disability. During military service, Service members are exposed to many differ...

Age-Related Vestibular and Ocular Motor Outcomes Following a Sport-Related Concussion.

May 13, 2021

Vestibular and ocular motor assessment is an emerging clinical assessment for sport-related concussion (SRC). The increased use of these assessments by clinicians calls for examination of outcomes in ...

Patient-Reported Outcomes in Cardiovascular Trials.

May 13, 2021

Patient-reported outcomes (PROs) are reports of a person's health status that provide a global perspective of patient well-being. PROs can be classified into four primary domains: global, mental, phys...

Mis-reporting of energy intake among older Australian adults: Prevalence, characteristics, and associations with quality of life.

May 13, 2021

Mis-reporting is common in dietary assessment, leading to misinterpretation of disease risk and could be important in older adults with increased chronic disease risk. This study investigated the prev...

Hospital-Acquired Infections in Critically Ill Patients With COVID-19.

May 13, 2021

Few small studies have described hospital-acquired infections (HAIs) occurring in patients with COVID-19.What characteristics in critically ill patients with COVID-19 are associated with HAIs and how ...

Dr. MedLaw: Docs on a plane - Dealing with in-flight emergencies

May 12, 2021

As we emerge from our COVID isolation, air travel is beginning to boom again, and many doctors are concerned about what happens when there is an in-flight emergency. Let’s take a look at that. ...

CLINICAL AND GENETIC FACTORS OF CARDIOVASCULAR EVENTS DEVELOPMENT AFTER PERCUTANEOUS CORONARY INTERVENTION.

May 10, 2021

The new cardiovascular events development remains the main factors limiting its long-term effectiveness despite technological progress and the widespread use of percutaneous coronary intervention (PCI...

Extracorporeal photopheresis vs standard therapies for steroid-refractory chronic graft-vs-host disease: Pharmacoeconomic assessment of hospital resource use in Spain.

May 10, 2021

This study assessed pharmacoeconomic costs associated with extracorporeal photopheresis (ECP) compared with other available second-line therapies for chronic graft-vs-host disease (cGvHD) in a tertiar...

Energy management and mitochondrial dynamics in cerebral cortex during endotoxemia.

May 10, 2021

Mitochondria play an essential role in inflammatory processes such as sepsis or endotoxemia, contributing to organ-cellular redox metabolism, emerging as the energy hub of the cell, and as an importan...

Identification of distinct clinical subphenotypes in critically ill patients with COVID-19.

May 10, 2021

Subphenotypes have been identified in patients with sepsis and acute respiratory distress syndrome (ARDS), and are associated with different outcomes and response to therapies.Can unique subphenotypes...

3-month, 6-month, 9-month, and 12-month respiratory outcomes in patients following COVID-19-related hospitalisation: a prospective study.

May 10, 2021

The consequences of COVID-19 in those who recover from acute infection requiring hospitalisation have yet to be clearly defined. We aimed to describe the temporal trends in respiratory outcomes over 1...

Outcomes of hematopoietic cell transplantation (HCT) in patients with mixed response to treatment of confirmed or suspected invasive fungal infection before HCT.

May 10, 2021

Patients with hematologic malignancy or bone marrow failure are typically required to achieve radiographic improvement or stabilization of invasive fungal infection (IFI) prior to hematopoietic cell t...

[COMPLEX TREATMENT OF PATIENTS WITH VENOUS TROPHIC ULCER IN THE CONDITIONS OF COVID-19 HOSPITAL].

May 10, 2021

The aim of the study was to study the effectiveness of complex treatment of decompensated chronic venous insufficiency (CVI) using innovative techniques and proteolysis inhibitors with a wide spectrum...

COULD GENDER IMPACT ON IMMEDIATE AND LONG-TERM CAROTID ARTERY STENTING OUTCOME? INSIGHT FROM AN ITALIAN SINGLE CENTER EXPERIENCE.

May 10, 2021

Carotid artery stenting (CAS) has become a valid alternative to carotid endarterectomy in stroke prevention. However, female gender is still considered as an independent risk factor for CAS procedures...

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