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Critical Care General

The effect of Guanxin Shutong capsule on alleviating the myocardial fibrosis in heart failure rats.

May 03, 2021

Guanxin Shutong (GXST) capsule is a renowned traditional Chinese medicine widely used for the treatment of cardiovascular diseases in the clinic. However, no pharmacological experimental studies of GX...

Cerebral blood flow, cerebrovascular reactivity, and their influence on ventilatory sensitivity.

May 03, 2021

What is the topic of this review? Cerebrovascular reactivity to CO is a principle factor in determining ventilatory responses to CO through the role reactivity plays in determining cerebral extra- and...

Performance of an Electronic Decision Support System as a Therapeutic Intervention During a Multicenter PICU Clinical Trial: Heart and Lung Failure-Pediatric Insulin Titration trial (HALF-PINT).

May 03, 2021

The use of electronic clinical decision support (CDS) systems for pediatric critical care trials is rare. We sought to describe in detail the use of a CDS tool (Children's Hospital Euglycemia for Kids...

Crystal Volume: A Biomarker for Cardiovascular Risk in Gout

Apr 29, 2021

“The relationship between gout and cardiovascular (CV) disease risk is central to the management of gout, since patients with gout have a six-fold higher risk of suffering from CV events compared wi...

A Systematic Review and Meta-Analysis of Outcomes After Acute Limb Ischemia in Patients with Cancer.

Apr 29, 2021

Cancer results in a hypercoagulable state that is associated with both venous and arterial thromboses, but little is known about the impact of acute limb ischemia (ALI) in this cohort of patients. The...

Mechanical thrombectomy injury to the arterial wall: A comparison between catheter aspiration and stent retriever.

Apr 29, 2021

To compare the extent of arterial wall damage when SR and CA were used for treatment of AIS models to evaluate their efficacy and safety.A thrombin-induced thrombus was pre-injected into the right dis...

The role of emptying services in provision of safely managed sanitation: A classification and quantification of the needs of LMICs.

Apr 29, 2021

Classifications for onsite sanitation in terms of facility type (septic tanks, pit latrines) exist, but connecting these facilities to the wider sanitation value chain via improved containment, emptyi...

Comparison of children receiving emergent sepsis care by mode of arrival.

Apr 29, 2021

To determine if differences in patient characteristics, treatments, and outcomes exist between children with sepsis who arrive by emergency medical services (EMS) versus their own mode of transport (s...

Menstrual toxic shock syndrome: a French nationwide multicenter retrospective study.

Apr 29, 2021

Studies describing the clinical features and short-term prognosis of patients admitted to the intensive care unit (ICU) for menstrual toxic shock syndrome (m-TSS) are lacking.This was a multicenter re...

Risk of developing pneumonia associated with clinically diagnosed hypothyroidism: a nationwide population-based cohort study.

Apr 29, 2021

Hypothyroidism has a detrimental effect on the immune system, which may predispose patients to infection. However, evidence about the risk of developing either community- or hospital-acquired pneumoni...

A rare cause of esophagopleural fistula due to intensity-modulated proton therapy: a case report and review of literature.

Apr 29, 2021

Esophagopleural fistula (EPF), initially described in 1960, is an abnormal communication between the esophagus and the pleural cavity which can occur due to congenital malformation or acquired due to ...

Isoxanthanol alleviates Staphylococcus aureus induced chronic obstructive pulmonary disease in rat model through promotion of miR-145-5p expression.

Apr 29, 2021

The present study was aimed to evaluate the isoxanthanol against Staphylococcus aureus chronic obstructive pulmonary disease (COPD) in rat model. The isoxanthanol decreased the parasitic load by almos...

Disease-dependent variations in the timing and causes of readmissions in Germany: A claims data analysis for six different conditions.

Apr 29, 2021

Hospital readmissions place a major burden on patients and health care systems worldwide, but little is known about patterns and timing of readmissions in Germany.We used German health insurance claim...

Predictive Value of Clinician "Gestalt" in Pediatric Community-Acquired Pneumonia.

Apr 29, 2021

Validated prognostic tools for pediatric community-acquired pneumonia (CAP) do not exist. Thus, clinicians rely on "gestalt" in management decisions for children with CAP. We sought to determine the a...

Idiopathic ileal volvulus with multiple concomitant infections in a starving man.

Apr 29, 2021

Small bowel volvulus is defined as the torsion of the small intestine, potentially leading to bowel obstruction, gangrene and perforation. It is a rare condition, especially in adults.A 30-year-old ma...

Predicting candidate therapeutic drugs for sepsis-induced acute respiratory distress syndrome based on transcriptome profiling.

Apr 29, 2021

Sepsis-induced acute respiratory distress syndrome (ARDS) remains a major threat to human health without effective therapeutic drugs. Previous studies demonstrated the power of gene expression profili...

Basal Cisternostomy - A Microsurgical Cerebro Spinal Fluid Let Out Procedure and Treatment Option in the Management of Traumatic Brain Injury. Analysis of 40 Consecutive Head Injury Patients Operated with and without Bone Flap Replacement Following Cisternostomy in a Tertiary Care Centre in India.

Apr 29, 2021

Decompressive craniectomy (DC) is considered the gold standard blanket surgical procedure for all medically intractable cerebral oedema in Traumatic Brain Injury (TBI). It's only proven fact is that i...

Association of Sex With Adolescent Soccer Concussion Incidence and Characteristics.

Apr 29, 2021

Because of the negative consequences of concussion, considerable research efforts have been directed toward understanding the risk factors for sport-related concussion (SRC) and its outcomes to better...

Visuo-motor integration, vision perception and attention in mTBI patients. Preliminary findings.

Apr 29, 2021

Patients with mild traumatic brain injuries (mTBI) often report difficulties in motor coordination and visuo-spatial attention. However, the consequences of mTBI on fine motor and visuo-motor coordina...

Compromised right ventricular contractility in an ovine model of heart transplantation following 24hours donor brain stem death.

Apr 29, 2021

Heart failure is an inexorably progressive disease with a high mortality, for which heart transplantation (HTx) remains the gold standard treatment. Currently, donor hearts are primarily derived from ...

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