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Critical Care General

Aorto-left atrial fistula secondary to infective aortic endocarditis and endarteritis in a cat with valvular aortic stenosis.

Apr 29, 2021

A cat previously diagnosed with valvular aortic stenosis developed acute respiratory distress. A new continuous heart murmur was noted on physical exam. Echocardiographic examination revealed vegetati...

Endothelial ether lipids link the vasculature to blood pressure, behavior, and neurodegeneration.

Apr 26, 2021

Vascular disease contributes to neurodegeneration, which is associated with decreased blood pressure in older humans. Plasmalogens, ether phospholipids produced by peroxisomes, are decreased in Alzhei...

Mortality, neurodevelopmental impairments, and economic outcomes after invasive group B streptococcal disease in early infancy in Denmark and the Netherlands: a national matched cohort study.

Apr 26, 2021

Group B Streptococcus (GBS) disease is a leading cause of neonatal death, but its long-term effects have not been studied after early childhood. The aim of this study was to assess long-term mortality...

Anesthetics isoflurane and sevoflurane attenuate flagellin-mediated inflammation in the lung.

Apr 26, 2021

Isoflurane and sevoflurane are volatile anesthetics (VA) widely used in clinical practice to provide general anesthesia. We and others have previously shown that VAs have immunomodulatory effects and ...

Occult primary Sjögren Syndrome in patients with interstitial pneumonia with autoimmune features.

Apr 26, 2021

To define the performance of Minor Salivary Gland Biopsy (MSGB) and Dry Eye Tests (DET) to detect occult Sjögren Syndrome (SS) among Interstitial Pneumonia with Autoimmune Features (IPAF) patients.Pr...

Investigating centering, scan length, and arm position impact on radiation dose across 4 countries from 4 continents during pandemic: Mitigating key radioprotection issues.

Apr 26, 2021

Optimization of CT scan practices can help achieve and maintain optimal radiation protection. The aim was to assess centering, scan length, and positioning of patients undergoing chest CT for suspecte...

Serum calcium and long-term outcome after ischemic stroke: Results from the China National stroke registry III.

Apr 26, 2021

Serum calcium abnormality is associated with adverse cardiovascular outcomes, but the effects of serum calcium level on stroke outcomes remain unknown. We aimed to assess the relationship between seru...

Effectiveness of Chlamydia Trachomatis expedited partner therapy in pregnancy.

Apr 26, 2021

Expedited partner therapy for chlamydia trachomatis has had mixed efficacy in different populations, but data are lacking on the efficacy in a pregnant population.Evaluate the real-world effectiveness...

The Role of Mitophagy in Pulmonary Sepsis.

Apr 26, 2021

Sepsis is a systemic inflammatory disease with an unacceptably high mortality rate caused by an infection or trauma that involves both innate and adaptive immune systems. Inflammatory events activate ...

Association of Clinical Guidelines and Decision Support with CT use in Pediatric Mild Traumatic Brain Injury.

Apr 26, 2021

To examine whether the presence of clinical guidelines and clinical decision support (CDS) for mild traumatic brain injury (mTBI) are associated with lower head computed tomography (CT) use.We conduct...

Tau aggregation and increased neuroinflammation in athletes after sports-related concussions and in traumatic brain injury patients - A PET/MR study.

Apr 26, 2021

Traumatic brain injury (TBI) and repeated sports-related concussions (rSRCs) are associated with an increased risk for neurodegeneration. Autopsy findings of selected cohorts of long-term TBI survivor...

Potential anti-inflammatory effect of erythropoietin in non-clinical studies in vivo: A systematic review.

Apr 26, 2021

Erythropoietin (EPO) is a hypoxia-induced hormone produced in adult kidneys with erythropoietic and non-erythropoietic effects. In vivo studies represent an important role to comprehend the efficacy a...

"Determinants of treatment modification before and after implementation of the updated 2015 NICE guideline on type 2 diabetes: a retrospective cohort study".

Apr 26, 2021

To identify patient-specific factors associated with early metformin treatment modification among type 2 diabetes patients before and after implementation of the updated 2015 NICE (National Institute ...

Changes in Pediatric ICU Utilization and Clinical Trends During the Coronavirus Pandemic.

Apr 26, 2021

Children have been less affected by the COVID-19 pandemic, but its repercussions on pediatric illnesses may have been significant. This study examines the indirect impact of the pandemic on a populati...

The Impacts of Statin Use on Physical Function in Men With & Without HIV

Apr 23, 2021

With an increasing prevalence of older adults living with HIV, thanks to the effectiveness of ART, so too has the prevalence of age-related chronic illnesses—including cardiovascular disease (CVD)�...

Alberta Stroke Program Early CT Score Calculation Using the Deep Learning-Based Brain Hemisphere Comparison Algorithm.

Apr 22, 2021

The Alberta Stroke Program Early Computed Tomography Score (ASPECTS) is a promising tool for the evaluation of stroke expansion to determine suitability for reperfusion therapy. The aim of this study ...

25-Hydroxycholesterol mitigates hepatic ischemia reperfusion injury via mediating mitophagy.

Apr 22, 2021

Hepatic ischemia reperfusion (I/R) injury remains a major obstacle in liver transplantation, however an effective treatment to mitigate this injury is lacking. 25-Hydroxycholesterol (25HC) is a kind o...

Latency Period after Preterm Premature Rupture of Membranes: Singletons versus Twins.

Apr 22, 2021

 Several studies have evaluated the differences in duration of latency and clinical outcomes between singleton and twin pregnancies after preterm premature rupture of membranes (PPROM); however, the...

Altered Fibrinolysis during and after Surgery.

Apr 22, 2021

Major surgery induces hemostatic changes related to surgical stress, tissue destruction, and inflammatory reactions. These changes involve a shift of volume from extravascular space to intravascular a...

Identifying prognostic factors and developing accurate outcome predictions for in-hospital cardiac arrest by using artificial neural networks.

Apr 22, 2021

Accurate estimation of neurological outcomes after in-hospital cardiac arrest (IHCA) provides crucial information for clinical management. This study used artificial neural networks (ANNs) to determin...

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