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Critical Care General

Low density neutrophils in chronic graft versus host disease (cGVHD) are primarily immature CD10 and enhance T-cell activation.

May 03, 2021

Chronic graft-versus-host disease (cGVHD) is a frequent complication of allogeneic haematopoietic stem cell transplantation. Low density neutrophils (LDNs) in autoimmunity, which shares disease featur...

Aquatic toxicity of waterpipe wastewater chemicals.

May 03, 2021

The recent increase in U.S. popularity and use prevalence of water pipe (WP) tobacco smoking raises concerns about the potential environmental impacts of WP waste disposal and the need for strategies ...

LncRNA NKILA knockdown promotes cell viability and represses cell apoptosis, autophagy and inflammation in lipopolysaccharide-induced sepsis model by regulating miR-140-5p/CLDN2 axis.

May 03, 2021

Long non-coding RNAs (lncRNAs) play vital roles in human diseases, including sepsis-induced acute kidney injury (AKI). Here, we aimed to investigate the functions of lncRNA NKILA in sepsis-engendered ...

Phytochemistry and pharmacological activities of Arundina graminifolia (D.Don) Hochr. and other common Orchidaceae medicinal plants.

May 03, 2021

Arundina graminifolia (Orchidaceae) has been widely used for heat clearance and detoxification, anti-inflammatory diuretic, and anti-microbes for two thousand years in national minorities, especially ...

Nanotechnology-based approaches for emerging and re-emerging viruses: Special emphasis on COVID-19.

May 03, 2021

In recent decades, the major concern of emerging and re-emerging viral diseases has become an increasingly important area of public health concern, and it is of significance to anticipate future pande...

CT-Based COVID-19 triage: Deep multitask learning improves joint identification and severity quantification.

May 03, 2021

The current COVID-19 pandemic overloads healthcare systems, including radiology departments. Though several deep learning approaches were developed to assist in CT analysis, nobody considered study tr...

Long-Term Clinical Outcomes and Carotid Ultrasound Follow-Up of Transcarotid TAVI. Prospective Single-Center Registry.

May 03, 2021

This study aimed to prospectively evaluate the safety and long-term clinical outcomes of cerebral-oximetry-guided transcarotid transcatheter aortic valve implantation (TC-TAVI) with systematic follow-...

Eggerthia catenaformis infection originating from a dental abscess causes severe intestinal complications and osteomyelitis of the jaw.

May 03, 2021

Odontogenic foci may result to generalized infections spreading the bacteria through contiguous anatomic cavities or hematogenous spread. The most reported secondary infections caused by oral pathoge...

Can Topical Vancomycin Prevent Periprosthetic Joint Infection in Hip and Knee Arthroplasty? A Systematic Review.

May 03, 2021

Periprosthetic joint infection (PJI) after hip and knee arthroplasty is a leading cause of revision surgery, inferior function, complications, and death. The administration of topical, intrawound vanc...

The attenuation of Th1 and Th17 responses via autophagy protects against methicillin-resistant Staphylococcus aureus-induced sepsis.

May 03, 2021

Whether autophagy affects methicillin-resistant Staphylococcus aureus (MRSA)-induced sepsis and the associated mechanisms are largely unknown. This study investigated the role of autophagy in MRSA-ind...

Contemporary insight into diffuse axonal injury.

May 03, 2021

Diffuse axonal injury (DAI) is present in approximately 50% of the cases with severe traumatic brain injury. It is one of the leading causes of morbidity and mortality among children and young individ...

Neuroprotective response and efficacy of intravenous administration of mesenchymal stem cells in traumatic brain injury mice.

May 03, 2021

Cellular transplantation of stem cells can be a beneficial treatment approach for neurodegenerative diseases such as traumatic brain injury (TBI). In this study, we investigated the proliferation and ...

Ability of serum annexin A1 to predict 6-month poor clinical outcome following aneurysmal subarachnoid hemorrhage.

May 03, 2021

Annexin A1 might be neuroprotective and serum annexin A1 concentrations were markedly declined after severe traumatic brain injury. We determine dthe ability of serum annexin A1 to assess severity and...

Histone deacetylase 3 suppresses the expression of SHP-1 via deacetylation of DNMT1 to promote heart failure.

May 03, 2021

Heart failure (HF) is a progressive disease with recurrent hospitalizations and high mortality. However, the mechanisms underlying HF remain unclear. The present study aimed to explore the regulatory ...

The effect of Guanxin Shutong capsule on alleviating the myocardial fibrosis in heart failure rats.

May 03, 2021

Guanxin Shutong (GXST) capsule is a renowned traditional Chinese medicine widely used for the treatment of cardiovascular diseases in the clinic. However, no pharmacological experimental studies of GX...

Cerebral blood flow, cerebrovascular reactivity, and their influence on ventilatory sensitivity.

May 03, 2021

What is the topic of this review? Cerebrovascular reactivity to CO is a principle factor in determining ventilatory responses to CO through the role reactivity plays in determining cerebral extra- and...

Performance of an Electronic Decision Support System as a Therapeutic Intervention During a Multicenter PICU Clinical Trial: Heart and Lung Failure-Pediatric Insulin Titration trial (HALF-PINT).

May 03, 2021

The use of electronic clinical decision support (CDS) systems for pediatric critical care trials is rare. We sought to describe in detail the use of a CDS tool (Children's Hospital Euglycemia for Kids...

Crystal Volume: A Biomarker for Cardiovascular Risk in Gout

Apr 29, 2021

“The relationship between gout and cardiovascular (CV) disease risk is central to the management of gout, since patients with gout have a six-fold higher risk of suffering from CV events compared wi...

A Systematic Review and Meta-Analysis of Outcomes After Acute Limb Ischemia in Patients with Cancer.

Apr 29, 2021

Cancer results in a hypercoagulable state that is associated with both venous and arterial thromboses, but little is known about the impact of acute limb ischemia (ALI) in this cohort of patients. The...

Mechanical thrombectomy injury to the arterial wall: A comparison between catheter aspiration and stent retriever.

Apr 29, 2021

To compare the extent of arterial wall damage when SR and CA were used for treatment of AIS models to evaluate their efficacy and safety.A thrombin-induced thrombus was pre-injected into the right dis...

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