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Critical Care General

Antibiotics in treatment of COVID-19 complications: a review of frequency, indications, and efficacy.

Apr 15, 2021

To report available information in the literature regarding frequency, indications, types of antibiotic usage, duration, and their efficacy in Covid-19 infected patients.The search was conducted on Ap...

A Before-and-After Study of Evidence-Based Recommendations for On-Call Bronchoscopy.

Apr 15, 2021

Bronchoscopy is widely used and regarded as standard of care in most intensive care units (ICUs). Data concerning recommendations for on-call bronchoscopy are lacking.Evaluation of recommendations, co...

Detection of Myocardial Infarction by Cardiac Magnetic Resonance in Embolic Stroke Related to First Diagnosed Atrial Fibrillation.

Apr 15, 2021

Elevated troponin levels are found in a significant number of patients who are diagnosed with acute embolic stroke (AES) after first diagnosed atrial fibrillation (AF). These myocardial injuries, whic...

External stenting of vein grafts in coronary artery bypass grating: interim results from a two centers prospective study.

Apr 15, 2021

previous studies evaluating external stents for saphenous vein grafts (SVG) in CABG were limited to on-pump isolated CABG and single grafting technique with one external stent per patient. The objecti...

Prophylactically injection of Nicorandil to reduce no-reflow phenomenon during PCI in acute STEMI patients: Protocol of a double-blinded, randomized, placebo-controlled trial.

Apr 15, 2021

An acute ST-elevation myocardial infarction (STEMI) is a very serious type of heart attack and a profoundly life-threatening medical emergency, and percutaneous coronary intervention (PCI) is the pref...

Role of Mitochondria-Derived Danger Signals Released after Injury in Systemic Inflammation and Sepsis.

Apr 15, 2021

Sepsis is a major public health concern, with high mortality and morbidity, especially among trauma patients. It is characterized by a systemic inflammatory response syndrome (SIRS) occurring in respo...

A case report on death from acute bacterial cholangitis accompanied by von Meyenburg complexes: Use of 16S rRNA gene sequencing to identify pathogenic microbes from postmortem formalin-fixed, paraffin-embedded tissue.

Apr 15, 2021

In some cases, autopsy is the first opportunity to find a previously unrecognized critical infection. Pathogens are identified by various methods, such as microscopic examination, special stains, cult...

TREM2 Dictates Antibacterial Defense and Viability of Bone Marrow-derived Macrophages During Bacterial Infection.

Apr 15, 2021

Macrophages undergo profound metabolic reprogramming to join key immunoregulatory functions, which can be initiated by pattern recognition receptors. TREM2, a macrophage phagocytic receptor, plays piv...

Sex-Based Differences in Symptoms with Mouthguard Use Following Pediatric Sport-Related Concussion.

Apr 15, 2021

Current evidence regarding the protective effect of mouthguard use on symptom severity in children and adolescents who sustain sport-related concussions is insufficient to make clinical recommendation...

An Evaluation of Pediatric Secondary Overtriage in the Pennsylvania Trauma System.

Apr 15, 2021

We sought to determine the secondary overtriage rate of pediatric trauma patients admitted to pediatric trauma centers. We hypothesized that pediatric secondary overtriage (POT) would constitute a lar...

Repetitive Mild Traumatic Brain Injury in a Perinatal Nicotine Exposure Mouse Model of Attention Deficit Hyperactivity Disorder.

Apr 15, 2021

Attention deficit hyperactivity disorder (ADHD) increases the risk for concussion or mild traumatic brain injury (mTBI). At the same time, recommendations for the management of ADHD include participat...

Lung Ultrasound Surface Wave Elastography for Assessing Patients with Pulmonary Edema.

Apr 15, 2021

Ultrasound insonation of lungs that are dense with extravascular lung water (EVLW) produces characteristic reverberation artifacts termed B-lines. The number of B-lines present demonstrates reasonable...

Ghrelin attenuates depressive-like behavior, heart failure, and neuroinflammation in postmyocardial infarction rat model.

Apr 15, 2021

Depression after myocardial infarction (MI) and chronic heart failure (CHF) is a common condition that is resistant to anti-depressive drugs. Ghrelin (a peptide hormone) shows dual protective effects ...

A call to caution when hydroxychloroquine is given to elderly COVID-19 patients.

Apr 15, 2021

Hydroxychloroquine use in COVID-19 patients was widespread and uncontrolled until recently. Patients vulnerable to severe COVID-19 are at risk for hydroxychloroquine interactions with comorbidities an...

Medical Fiction: Darko and Toaster Tim - A Dance With the Devil

Apr 12, 2021

This is one of a collection of stories that are like “Final Destination” meets “The Monkey’s Paw” (W. W. Jacobs, 1902). As such, they are tragedies more than either mysteries or horror, an...

Hyperspectral imaging and indocyanine green fluorescence angiography in acute mesenteric ischemia: A case report on how to visualize intestinal perfusion.

Apr 12, 2021

Acute mesenteric ischemia is a challenging acute condition which is often caused by occlusion of an intestinal vessel. Therapeutic algorithms include revascularization of the occluded vessel and a sur...

Therapeutic plasma exchange in patients with life-threatening COVID-19: a randomized control clinical trial.

Apr 12, 2021

To assess the efficacy of therapeutic plasma exchange (TPE) following life-threatening COVID-19.Open-label, randomized clinical trial of intensive care unit (ICU) patients with life-threatening COVID-...

Innate immune memory mediates increased susceptibility to Alzheimeŕs disease-like pathology in sepsis surviving mice.

Apr 12, 2021

Sepsis survivors show long-term impairments, including alterations in memory and executive function. Evidence suggests that systemic inflammation contributes to the progression of Alzheimeŕs disease ...

The place in therapy of ceftazidime/avibactam and ceftolozane/tazobactam in hematological patients with febrile neutropenia.

Apr 12, 2021

We evaluate ceftazidime/avibactam (C/A) and ceftolozane/tazobactam (C/T) use in hematological patients with febrile neutropenia (FN) receiving high-dose chemotherapy and HSCT.Between January-December ...

The effect of environmental diesel exhaust pollution on SARS-CoV-2 infection: The mechanism of pulmonary ground glass opacity.

Apr 12, 2021

Diesel exhaust particles (DEP) are the major components of atmospheric particulate matter (PM) and chronic exposure is recognized to enhance respiratory system complications. Although the spread of SA...

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