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Critical Care General

[Coronary artery bypass grafting in myocardial infarction and unstable angina pectoris: in-hospital outcomes. Part 2].

Apr 12, 2021

To assess in-hospital outcomes of coronary artery bypass grafting in patients with acute coronary syndrome, depending on the presence or absence of myocardial infarction.Over the period from 2017 to 2...

Linked electronic health records for research on a nationwide cohort of more than 54 million people in England: data resource.

Apr 12, 2021

To describe a novel England-wide electronic health record (EHR) resource enabling whole population research on covid-19 and cardiovascular disease while ensuring data security and privacy and maintain...

A Systematic Review of the Association Between Vegan Diets and Risk of Cardiovascular Disease.

Apr 12, 2021

Plant-based diets are gaining attention globally due to their environmental benefits and perceived health-protective role. A vegan diet may have cardiovascular benefits; however, evidence remains conf...

Role of a thrombin generation assay in the prediction of infection severity.

Apr 12, 2021

Thrombin plays a central role in sepsis pathophysiology. The correlation of thrombin generation (TG) assays with infection severity and prognosis, and whether it can be used as a clinical tool, have b...

Capturing Cytokines with Advanced Materials: A Potential Strategy to Tackle COVID-19 Cytokine Storm.

Apr 12, 2021

The COVID-19 pandemic, induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused great impact on the global economy and people's daily life. In the clinic, most patients with...

An Antibacterial Nanorobotic Approach for the Specific Targeting and Removal of Multiple Drug-Resistant Staphylococcus aureus.

Apr 12, 2021

Methicillin-resistant Staphylococcus aureus (MRSA) causes diseases ranging from skin infections to lethal sepsis and has become a serious threat to human health due to multiple-drug resistance (MDR). ...

Injury Severity, Arrival Physiology, Coagulopathy, and Outcomes Among the Youngest Trauma Patients.

Apr 12, 2021

Although physiologic differences exist between younger and older children, pediatric trauma analyses are weighted toward older patients. Trauma-induced coagulopathy, determined by rapid thrombelastogr...

Vergence, accommodation, and visual tracking in children and adolescents evaluated in a multidisciplinary concussion clinic.

Apr 12, 2021

Many patients with concussion experience visual symptoms following injury that lead to a diagnosis of convergence insufficiency, accommodative insufficiency, or saccadic dysfunction. However, these di...

A novel role of claudin-5 in prevention of mitochondrial fission against ischemic/hypoxic stress in cardiomyocytes.

Apr 12, 2021

Downregulation of claudin-5 in the heart is associated with the end-stage heart failure. However, the underlying mechanism of claudin-5 is unclear. Here we investigated the molecular actions of claudi...

Iron deficiency is associated with impaired biventricular reserve and reduced exercise capacity in patients with unexplained dyspnea.

Apr 12, 2021

Iron deficiency (ID) is frequent and associated with diminished exercise capacity in heart failure (HF), but its contribution to unexplained dyspnea without a HF diagnosis at rest remains unclear.Cons...

Vascular access for renal replacement therapy among 459 critically ill patients: a pragmatic analysis of the randomized AKIKI trial.

Apr 12, 2021

Vascular access for renal replacement therapy (RRT) is routine question in the intensive care unit. Randomized trials comparing jugular and femoral sites have shown similar rate of nosocomial events a...

Mild Primary Hyperparathyroidism Linked With Adverse Cardiovascular Events

Apr 08, 2021

“The relationship between mild primary hyperparathyroidism (pHPT) and cardiovascular (CV) disease has not been fully understood,” explains Stella Bernardi, MD, PhD. “Previous research has shown ...

Transient global amnesia: Signal alteration in 2D/3D T2-FLAIR sequences.

Apr 08, 2021

Transient global amnesia (TGA) is one of the most enigmatic syndromes in clinical neurology. The detection rate of TGA lesions in 2D/3D FLAIR sequences has not been evaluated.A total of 201 patients (...

Heparin binding protein in severe COVID-19-A prospective observational cohort study.

Apr 08, 2021

Neutrophil-derived heparin binding protein (HBP; also known as azurocidin or CAP-37) is a key player in bacterial sepsis and a promising biomarker in severe infections. The aims of this study were to ...

Regulated hypothermia in response to endotoxin in birds.

Apr 08, 2021

The costs associated with immune and thermal responses may exceed its benefits to the host during severe inflammation. In this case, regulated hypothermia instead of fever can occur in rodents as a be...

Treatment-dose LMWH versus prophylactic/intermediate dose heparins in high risk COVID-19 inpatients: Rationale and design of the HEP-COVID Trial.

Apr 08, 2021

Coronavirus disease-2019 (COVID-19) has been associated with significant risk of venous thromboembolism (VTE), arterial thromboembolism (ATE), and mortality particularly among hospitalized patients wi...

The role of pirfenidone in the treatment of interstitial pneumonia with autoimmune features.

Apr 08, 2021

No approved pharmacotherapies are available for patients with interstitial pneumonia with autoimmune features (IPAF). In the present work, we aimed to evaluate the efficacy and safety of pirfenidone f...

Awake venoarterial extracorporeal membrane oxygenation for refractory cardiogenic shock.

Apr 08, 2021

Venoarterial-extracorporeal membrane oxygenation (VA-ECMO) is currently one of the first-line therapies for refractory cardiogenic shock (CS), but its applicability is undermined by the high morbidity...

Diagnostic imaging in acute interstitial pneumonia in foals: High variability of interpretation of chest radiographs and good conformity between ultrasonographic and post-mortem findings.

Apr 08, 2021

Acute interstitial pneumonia (AIP) in foals is a rare but challenging syndrome. Diagnostic imaging is crucial for its diagnosis. While there are some reports on radiographic findings, ultrasound is sp...

Does Racial Disparity Exist Among Inpatient Admissions for Heart Attacks in Wisconsin?

Apr 08, 2021

Acute myocardial infarction (AMI), or heart attack, carries a high inpatient death risk. Few national studies suggest race affects the outcomes of inpatients with AMI. In Wisconsin, an assessment of r...

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