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Critical Care General

In vitro comparison of harvesting site effects on cardiac extracellular matrix hydrogels.

Apr 08, 2021

Cardiac extracellular matrix (cECM) derived hydrogel has been investigated to treat myocardial infarction through animal studies and clinical trials. The tissue harvesting site commonly selects porcin...

CT appearances of pleural infection: analysis of the Second Multi-centre Intra-pleural Sepsis Trial (MIST 2) cohort.

Apr 08, 2021

To determine the prevalence of pleural abnormalities and describe the computed tomography (CT) features observed in a well-characterised population of patients with pleural infection.A retrospective s...

Investigation and assessment of neutrophil dysfunction early after severe burn injury.

Apr 08, 2021

Extensive burn injury results in a complex immune response that is associated with mortality and prognosis. Studies on acquired immune and the development of sepsis in burn patients have been reported...

The RD2 pathogenicity island modifies the disease potential of the group A .

Apr 08, 2021

Serotype M28 isolates of the group A (GAS; ) are non-randomly associated with cases of puerperal sepsis, a potentially life-threatening infection that can occur in women following childbirth. Previou...

Predicting caregiver burden over the first 4 months after acute traumatic brain injury in Latin America: a multi-country study.

Apr 08, 2021

: Traumatic brain injury (TBI) rates and outcomes are worse in Latin American countries relative to high-income countries. This study examined whether cognitive dysfunction, depressive mood, and poor ...

Early Stage Longitudinal Subcortical Volumetric Changes following Mild Traumatic Brain Injury.

Apr 08, 2021

: To investigate early brain volumetric changes from acute to 6 months following mild traumatic brain injury (mTBI) in deep gray matter regions and their association with patient 6-month outcome.: Fi...

LITAF acts as a novel regulator for pathological cardiac hypertrophy.

Apr 08, 2021

Pathological hypertrophy generally progresses to heart failure. Exploring effective and promising therapeutic targets might lead to progress in preventing its detrimental outcomes. Our current knowled...

Weight change and the incidence of heart failure in the Korean population: data from the National Health Insurance Health checkup 2005-2015.

Apr 08, 2021

Heart failure (HF) is associated with obesity, but the relationship between weight change and HF is inconsistent. We examined the relationship between weight change and the incidence of HF in the Kore...

Emerging mechanisms and targeted therapy of ferroptosis in cancer.

Apr 05, 2021

Ferroptosis is an iron- and lipid ROS-dependent form of programmed cell death that is distinct from other forms of regulatory cell death at the morphological, biological and genetic levels. Emerging e...

Interleukin-6 in Amniotic Fluid: A Reliable Marker for Adverse Outcomes in Women in Preterm Labor and Intact Membranes.

Apr 05, 2021

Amniotic fluid (AF) interleukin-6 (IL-6) concentration has been associated to preterm delivery and perinatal morbidity and mortality in women with preterm labor and intact membranes. Nevertheless, the...

Endothelial Heparan Sulfate Proteoglycans in Sepsis: The Role of the Glycocalyx.

Apr 05, 2021

There is increasing recognition of the importance of the endothelial glycocalyx and its in vivo manifestation, the endothelial surface layer, in vascular homeostasis. Heparan sulfate proteoglycans (HS...

All Hands on Deck: Local Public Health Agencies Leveraging the Incident Command System During Crises.

Apr 05, 2021

The COVID-19 pandemic has stretched limited public health resources beyond measures, particularly at the local level. What started as an interesting report of pneumonia of unknown etiology in late Dec...

Fluoroscopy-Guided Salvage Photodynamic Therapy Combined with Nanoparticle Albumin-Bound Paclitaxel for Locally Advanced Esophageal Cancer after Chemoradiotherapy: A Case Report and Literature Review.

Apr 05, 2021

Among the total cancer deaths, esophageal cancer ranks sixth in mortality. Radiotherapy and chemotherapy remain the main treatments for unresectable, locally advanced esophageal cancer, but a relapse...

Hospitalization of mild cases of community-acquired pneumonia decreased more than severe ones during the COVID-19 epidemic.

Apr 05, 2021

The epidemic of the coronavirus disease 2019 (COVID-19) has affected the entire health care systems. Our aim was to assess the impact of the COVID-19 epidemic on the number and severity of cases for c...

Cardiovascular Responses During Sepsis.

Apr 05, 2021

Sepsis is the life-threatening organ dysfunction arising from a dysregulated host response to infection. Although the specific mechanisms leading to organ dysfunction are still debated, impaired tissu...

Baseline cardiometabolic profiles and SARS-CoV-2 infection in the UK Biobank.

Apr 05, 2021

SARS-CoV-2 is a rapidly spreading coronavirus responsible for the Covid-19 pandemic, which is characterized by severe respiratory infection. Many factors have been identified as risk factors for SARS-...

Pivotal role of endothelial cell autophagy in sepsis.

Apr 05, 2021

Sepsis is a fatal organ dysfunction resulting from a disordered host response to infection. Endothelial cells (ECs) are usually the primary targets of inflammatory mediators in sepsis; damage to ECs p...

Cost-effectiveness of immediate total-body CT in patients with severe trauma (REACT-2 trial).

Apr 05, 2021

The effect of immediate total-body CT (iTBCT) on health economic aspects in patients with severe trauma is an underreported issue. This study determined the cost-effectiveness of iTBCT compared with c...

Exploring the lived return-to-work experience of individuals with acquired brain injury: use of vocational services and environmental, personal and injury-related influences.

Apr 05, 2021

To explore work outcomes, vocational services, barriers and facilitators for returning to work in individuals with acquired brain injury (ABI) in Queensland, Australia and to identify areas for improv...

The concurrent validity and intrarater reliability of a hand-held dynamometer for the assessment of neck strength in semi-professional rugby union players.

Apr 05, 2021

The main objective of this study was to determine the concurrent validity between a hand-held (HHD) and mounted hand-held dynamometer (MHHD) for assessing isometric neck strength.Observational design....

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