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Critical Care General

Molecular characterization and antimicrobial resistance of group A streptococcus isolates in streptococcal toxic shock syndrome cases in Japan from 2013 to 2018.

Mar 25, 2021

Streptococcal toxic shock syndrome (STSS) is a severe invasive infection characterized by the sudden onset of shock, multi-organ failure, and puerperal sepsis and shows high mortality. Its primary cau...

Modulation of The Permeability-Inducing Factor Angiopoietin-2 Through Bifonazole in Systemic Inflammation.

Mar 25, 2021

Vascular barrier breakdown in sepsis represents a key component of the maladaptive host response to infection and the release of endothelial Angiopoietin-2 (Angpt-2) is a mechanistic driver of endothe...

Bone marrow transplant using fludarabine-based reduced intensity conditioning regimen with in vivo T cell depletion in patients with Fanconi anemia.

Mar 25, 2021

FA is the most common cause of inherited BMF syndromes. The only cure for BMF in FA remains HSCT. Due to DNA instability in FA, RIC has been used to decrease immediate and late complications of HSCT. ...

Reading Abilities Post Traumatic Brain Injury in Adolescents and Adults: A Systematic Review and Meta-Analysis.

Mar 25, 2021

Purpose People with traumatic brain injury (TBI) often struggle with complex reading, limiting participation in work and educational settings. This systematic review and meta-analysis examined studies...

Development of the traumatic brain injury Rehabilitation Needs Survey: a Veterans Affairs TBI Model Systems study.

Mar 25, 2021

To describe the development of the Rehabilitation Needs Survey (RNS) for persons in the chronic phase of traumatic brain injury (TBI) recovery.RNS items were generated following a literature review (J...

Cardiovascular impact and sequelae of bronchopulmonary dysplasia.

Mar 25, 2021

The development, growth, and function of the cardiac, pulmonary, and vascular systems are closely intertwined during both fetal and postnatal life. In utero, placental, environmental, and genetic insu...

Coronavirus disease in children: A multicentre study from the Kingdom of Saudi Arabia.

Mar 25, 2021

The COVID-19 global pandemic caused by severe acute respiratory syndrome coronavirus 2 infection, warranted attention for whether it has unique manifestations in children. Children tend to develop les...

Gender Linked With Outcomes in Acute Burn Injury Patients

Mar 23, 2021

“In high-income countries, men more often sustain burn injuries than women,” explains Lincoln M. Tracy, PhD. “The ratio is approximately two men for every woman. Despite this ratio, women have a...

Nonischemic or Ischemic Laparoscopic

Mar 22, 2021

The aim of this study is to qanalyze the viability of a recently evolved breed pencil-type energy gadget (HD) creating at the same time monopolar high-recurrence electric energy and ultrasonic energy ...

Alpinetin protects against hepatic ischemia/reperfusion injury in mice by inhibiting the NF-κB/MAPK signaling pathways.

Mar 22, 2021

Liver damage induced by ischemia/reperfusion (I/R) remains a primary issue in liver transplantation and resection. Alpinetin, a novel plant flavonoid derived from Alpinia katsumadai Hayata, is widely ...

Use of Intravenous Thrombolysis in Acute Ischemic Stroke Management in Patients with Active Malignancies: A Topical Review.

Mar 22, 2021

Our review aims to present existing data on the safety of Intravenous thrombolysis (IVT) use in acute ischemic stroke (AIS) patients with concomitant central nervous system or systemic malignancies, w...

Conservative management of spontaneous intra-abdominal abscess in Crohn's: outcome and prognostic factors.

Mar 22, 2021

This study compares the outcome of different treatment options for spontaneous intra-abdominal abscesses in active Crohn's disease.A retrospective analysis of Crohn's disease patients between January ...

COVID-19 and the human innate immune system.

Mar 22, 2021

The introduction of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into the human population represents a tremendous medical and economic crisis. Innate immunity-as the first line of def...

Host-dependent molecular factors mediating SARS-CoV-2 infection to gain clinical insights for developing effective targeted therapy.

Mar 22, 2021

Coronavirus disease 2019 (COVID-19), a recent viral pandemic that first began in December 2019, in Hunan wildlife market, Wuhan, China. The infection is caused by a coronavirus, SARS-CoV-2 and clinica...

Onasemnogene abeparvovec gene therapy for symptomatic infantile-onset spinal muscular atrophy in patients with two copies of SMN2 (STR1VE): an open-label, single-arm, multicentre, phase 3 trial.

Mar 22, 2021

Spinal muscular atrophy type 1 is a motor neuron disorder resulting in death or the need for permanent ventilation by age 2 years. We aimed to evaluate the safety and efficacy of onasemnogene abeparvo...

Progression from Pneumonia to ARDS as a Predictor for Fatal COVID-19.

Mar 22, 2021

There is a serious concern over the variation of case fatality of COVID-19 patients that reflects the preparedness of the medical care system in response to the surge of pneumonia patients. We aimed t...

Ventricular Assist Device Driveline Infection and Development of Intracranial Hemorrhage: A Case Series.

Mar 22, 2021

Durable left ventricular assist devices (LVAD) are frequently complicated by driveline infection. The objective of this case series was to examine whether an association exists between driveline infec...

Preliminary results: continuous double luminal catheter drainage for the management of septic hip arthritis in children.

Mar 22, 2021

Septic arthritis in children is considered an orthopedic surgical emergency, which requires prompt intervention to prevent later sequela. In the last decades, several minimal invasive techniques were ...

Serum cytokine profile of pediatric patients with laboratory confirmed pneumococcal meningitis.

Mar 22, 2021

Streptococcus pneumoniae infection is a leading cause of bacterial meningitis in children with severe sequelae. Cytokines are important molecules in regulating of host inflammatory and anti-inflammato...

Kick Start to an Epidemiological Report of Soccer-Related Craniofacial Trauma Analysis.

Mar 22, 2021

Soccer is a global sport played by millions annually with an increasing popularity in the United States. Game is played by a wide range of participants from all ages and levels of competition. This sc...

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