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Critical Care General

Development of brain atlases for early-to-middle adolescent collision-sport athletes.

Mar 22, 2021

Human brains develop across the life span and largely vary in morphology. Adolescent collision-sport athletes undergo repetitive head impacts over years of practices and competitions, and therefore ma...

Acute Mild Traumatic Brain Injury Assessment and Management in the Austere Setting-A Review.

Mar 22, 2021

Traumatic brain injury (TBI) continues to be a major source of military-related morbidity and mortality. The insidious short- and long-term sequelae of mild TBIs (mTBIs) have come to light, with ongoi...

Neprilysin inhibition does not alter dynamic of proenkephalin-A 119-159 and pro-substance P in heart failure.

Mar 22, 2021

As NEP degrades many substrates, the specific therapeutic mechanism of NEP inhibition with angiotensin receptor neprilysin inhibitor (ARNi) in heart failure with reduced ejection fraction (HFrEF) is n...

Dipeptidyl peptidase-3, a marker of the antagonist pathway of the renin-angiotensin-aldosterone system in patients with heart failure.

Mar 22, 2021

Recently, dipeptidyl peptidase 3 (DPP3) has been discovered as the peptidase responsible for cleavage of Angiotensin (1-7) (Ang (1-7)). Ang (1-7) is part of the ACE II - Angiotensin(1-7)- Mas (AAM) pa...

Italian Society of Interventional Cardiology (GIse) Registry Of Transcatheter Treatment of Mitral Valve RegurgitaTiOn (GIOTTO): Impact of Valve Disease Etiology and Residual Mitral Regurgitation after MitraClip Implantation.

Mar 22, 2021

The Italian Society of Interventional Cardiology (GIse) Registry Of Transcatheter Treatment of Mitral Valve RegurgitaTiOn (GIOTTO) was conceived in order to assess the safety and efficacy of the Mitra...

Changes in Pediatric Intensive Care Unit Utilization and Clinical Trends during the Coronavirus Pandemic.

Mar 22, 2021

Children have been less impacted by the Coronavirus disease 19 (COVID) pandemic, but its repercussions on pediatric illnesses may have been significant. We examined the indirect impact of the pandemic...

Extracellular volume fraction by T1 mapping predicts improvement of left ventricular ejection fraction after catheter ablation in patients with non-ischemic dilated cardiomyopathy and atrial fibrillation.

Mar 18, 2021

Absence of myocardial fibrosis on late gadolinium enhanced (LGE) magnetic resonance imaging (MRI) is associated with improvement of left ventricular systolic function after catheter ablation (CA) for ...

Incidence and risk factors of venous thromboembolism after percutaneous nephrolithotomy: a single-center experience.

Mar 18, 2021

To determine the incidence and risk factors of the venous thromboembolism (VTE) in patients undergoing percutaneous nephrolithotomy (PCNL).We retrospectively reviewed the records of 896 consecutive ca...

COVID-19 in patients with autoimmune diseases: characteristics and outcomes in a multinational network of cohorts across three countries.

Mar 18, 2021

Patients with autoimmune diseases were advised to shield to avoid COVID-19, but information on their prognosis is lacking. We characterised 30-day outcomes and mortality after hospitalisation with COV...

Covid-19 Interstitial Pneumonia: Histological and Immunohistochemical Features on Cryobiopsies.

Mar 18, 2021

The pathogenetic steps leading to Covid-19 interstitial pneumonia remain to be clarified. Most postmortem studies to date reveal diffuse alveolar damage as the most relevant histologic pattern. Antemo...

The Theoretical Value of Whole-Lung Irradiation for COVID-19 Pneumonia: A Reasonable and Safe Solution until Targeted Treatments are Developed.

Mar 18, 2021

In this work, we considered the theoretical role of low-dose radiation therapy (approximately 0.5-1.0 Gy) in the treatment of respiratory distress syndrome associated with COVID-19 infection. Monte Ca...

Neonatal Septic Shock and Hemodynamic Monitoring in Preterm Neonates in a NICU: Added Value of Electrical Cardiometry in Real-Time Tailoring of Management and Therapeutic Strategies.

Mar 18, 2021

 Electrical cardiometry is an impedance-based monitoring technique that provides data on several hemodynamic parameters in a noninvasive way. There is limited information on clinical utility of the ...

Toxic Metabolic Encephalopathy in Hospitalized Patients with COVID-19.

Mar 18, 2021

Toxic metabolic encephalopathy (TME) has been reported in 7-31% of hospitalized patients with coronavirus disease 2019 (COVID-19); however, some reports include sedation-related delirium and few data ...

Parechovirus Genotype 3 Outbreak Among Young Infants in Portugal.

Mar 18, 2021

Human parechovirus type 3 has been recognized as a cause of pediatric infection, occasionally associated with serious illness, including sepsis and meningitis, particularly among young infants. The a...

The Role of Social Support in Concussion Disclosure in United States Air Force Academy Cadets: A Mixed Methods Approach.

Mar 18, 2021

United States Air Force Academy (USAFA) cadets are at risk for sustaining concussions; however, several factors inhibit disclosure. We aimed to better understand the role of social support in concussi...

Allogeneic adipose-derived stem cells mitigate acute radiation syndrome by the rescue of damaged bone marrow cells from apoptosis.

Mar 18, 2021

Acute radiation syndrome (ARS) is the radiation toxicity that can affect the hematopoietic, gastrointestinal, and nervous systems upon accidental radiation exposure within a short time. Currently, the...

Biaxial softening of isolated cerebral arteries following axial overstretch.

Mar 18, 2021

Arteries play a critical role in carrying essential nutrients and oxygen throughout the brain; however, vessels can become damaged in traumatic brain injury (TBI), putting neural tissue at risk. Even ...

Clinical utility of CorVue intrathoracic impedance alert with device-measured physical activity in predicting heart failure events.

Mar 18, 2021

Cardiac implantable electronic devices (CIEDs) offer heart failure (HF) diagnostic information, including intrathoracic impedance (ITI) or physical activity (PA). However, few studies have evaluated t...

Actions taken by US hospitals to prepare for increased demand for intensive care during the first wave of COVID-19: A national survey.

Mar 18, 2021

The coronavirus disease 2019 (COVID-19) pandemic placed considerable strain on critical care resources. How United States (U.S.) hospitals responded to this crisis is unknown.What actions did U.S. hos...

The effectiveness of vitamin C for patients with severe viral pneumonia in respiratory failure.

Mar 18, 2021

Vitamin C is a well-known antioxidant and essential cofactor for numerous biological reactions. Several studies reported that vitamin C can improve the symptoms and prognosis of patients with sepsis a...

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