Mar 09, 2021

Data indicate that overuse of antibiotics is a main driver of antibiotic resistance, with every exposure to antibiotics creating a selection event with each patient’s microbiome, in turn, giving ris...

Mar 08, 2021

NOD-like receptor protein 3 (NLRP3) inflammasome is tightly related to the pathogenesis of cerebral ischemia/reperfusion (I/R) injury, and oridonin (Ori) has shown the potential to alleviate ischemia/...

Mar 08, 2021

Resveratrol has been reported to have beneficial effects on sepsis by regulating the inflammatory response. However, it remains unclear if resveratrol plays a role in the development of endotoxin tole...

Mar 08, 2021

The treatment of massive, irreparable rotator cuff tears remains controversial today since there is no consensus on the ideal treatment option. This investigation aimed to prospectively evaluate and c...

Mar 08, 2021

Dexmedetomidine (DEX) is a highly selective α2-adrenoceptor agonist, which can regulate inflammatory responses. However, whether DEX interferes with the inflammation resolving remains unclear. Here, ...

Mar 08, 2021

Mycoplasma bovis (M. bovis) is a small bacterium that lacks a cell wall. M. bovis infection can result in chronic pneumonia and polyarthritis syndrome (CPPS), otitis media, conjunctivitis, and meningi...

Mar 08, 2021

In the Tafamidis in Transthyretin Cardiomyopathy Clinical Trial (ATTR-ACT), tafamidis significantly reduced mortality and cardiovascular (CV)-related hospitalizations compared with placebo in patients...

Mar 08, 2021

To determine the risk of long-term major adverse cardiovascular events (MACE) when sleep-disordered breathing (SDB) and decreased cardiorespiratory fitness (CRF) co-occur.We included consecutive patie...

Mar 08, 2021

Transcarotid/transcervical revascularisation (TCAR) is an alternative to carotid endarterectomy (CEA) and transfemoral carotid stenting (tfCAS). This review aimed to evaluate pooled data on patients u...

Mar 08, 2021

sp. infection has appeared as a pathological burden in the population, but the immunomodulation features could result in an opportunity to discover novel treatments for diseases with prominent inflam...

Mar 08, 2021

To examine the association between body mass index (BMI) and mortality after hospitalization for infection because obesity is associated with increased energy reserves that may protect against death f...

Mar 08, 2021

To evaluate the incidence of nonunion and wound complications following open, complete articular pilon fractures. Second, to study the effect that both timing of fixation and timing of flap coverage h...

Mar 08, 2021

Minor head injury (MHI) in children is a common emergency department (ED) presentation. It is well established that majority of these patients don't require imaging and can be safely discharged. What ...

Mar 08, 2021

Children with traumatic head injury are often transferred from community Emergency Departments (ED) to a Pediatric Emergency Department (PED). The primary objective of this study was to describe the o...

Mar 08, 2021

Younger age at first exposure (AFE) to repetitive head impacts while playing American football increases the risk for later-life neuropsychological symptoms and brain alterations. However, it is not k...

Mar 08, 2021

Heart failure is one of the leading causes of death and disability worldwide. Left ventricle remodeling, fibrosis, and ischemia/reperfusion injury all contribute to the deterioration of cardiac functi...

Mar 08, 2021

Heart failure (HF) is the number one cause of death in the world. B-type natriuretic peptide (BNP) is a recognized biomarker for HF and can be used for early detection. Field effect transistor (FET) b...

Mar 08, 2021

Recent evidence indicates the relevant role of the tryptophan (TRP) metabolites in the pathophysiology of cardiovascular diseases via inflammatory and oxidative stress mechanisms. Therefore, quantific...

Mar 04, 2021

Sepsis is a systemic inflammatory response syndrome with high mortality. There is an upward trend in sepsis prevalence and mortality worldwide. Early and accurate prediction of outcome in sepsis is im...

Mar 04, 2021

The current article reviews recent findings on the monitoring and hemodynamic support of septic shock patients.The ultimate goal of hemodynamic resuscitation is to restore tissue oxygenation. A multim...