Piroxicam may augment the clinical efficacy of levonorgestrel in emergency contraception
Bookmark1. Levonorgestrel plus piroxicam resulted in significantly fewer pregnancies compared to...
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Emergency
Patients with anxiety and/or depression may not experience more emergency room visits following bariatric surgery
Bookmark1. In this retrospective cohort study, patients with a history of depression, anxiety, or...
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NaV1.8 inhibitor VX-548 reduces acute post-operative pain
Bookmark1. In this randomized controlled trial, the elective NaV1.8 inhibitor VX-548 reduced acute...
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Video laryngoscopy leads to higher success on first intubation attempt than direct laryngoscopy
Bookmark1. In this randomized controlled trial, video laryngoscopy in the context of critically...
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Recurrent injury is frequent among firearm injury survivors
Bookmark1. In this observational cohort study, recurrent injury was frequent among firearm injury...
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Indigenous females have worse emergency health outcomes even when off of reserve
Bookmark1. Compared to non-Indigenous Canadians, Indigenous females of reproductive age living off...
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Dupilumab reduces the number exacerbations in patients with COPD and type two inflammation
Bookmark1. In this randomized controlled trial, dupilumab use was associated with significantly...
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Biomarkers distinguish pediatric musculoskeletal infections from similar conditions
Bookmark 1. In a prospective cohort study, white blood cell (WBC) count, absolute neutrophil count...
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Post-cardiac arrest outcomes are similar following targeted hypercapnia versus normocapnia
Bookmark1. In this randomized controlled trial, for patients in a coma post-cardiac arrest,...
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Testosterone-replacement therapy noninferior to placebo for preventing cardiovascular events
Bookmark1. In this randomized controlled trial, in adults with hypogonadism and cardiovascular...
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Early detection and treatment of postpartum hemorrhage reduces associated complications
Bookmark1. In this randomized controlled trial, the E-MOTIVE bundle, consisting of early detection...
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Prehospital administration of tranexamic acid for major traumas does not improve outcomes
Bookmark1. In this randomized controlled trial, for adults with major trauma or trauma-induced...
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Indefinite anticoagulation for unprovoked venous thromboembolism is not cost-effective
Bookmark1. In this Markov modeling study, indefinite anticoagulation for first unprovoked venous...
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Early versus late post-stroke anticoagulation in patients with atrial fibrillation results in similar outcomes
Bookmark1. In this randomized controlled trial of patients with atrial fibrillation who had an...
Read MoreLongitudinal data shows that the opioid epidemic may be worsening in Ontario, Canada
Bookmark1. In a cross-sectional study, rates of opioid-related deaths were observed to rise among youths in Ontario, Canada between 2013-2021, while the use of opioid agonist therapy declined. Evidence Rating Level: 2 (Good)...
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Supervised hospital walking program reduces the need for nursing care
Bookmark1. A supervised walking program was associated with reduced discharge rates to...
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Tirofiban is associated with better post-stroke outcomes than low-dose aspirin
Bookmark1. In this randomized controlled trial, tirofiban was associated with better outcomes than...
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High-definition cathodal direct current stimulation for treatment of acute ischemic stroke
Bookmark1. High-definition cathodal direct current stimulation (HD C-tDCS) is a feasible and...
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Craniotomy and decompressive craniectomy comparable in managing acute subdural hematoma
Bookmark1. In this randomized controlled trial, craniotomy and decompressive craniectomy resulted...
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Withholding prophylactic platelet transfusion in thrombocytopenia increases adverse events
Bookmark1. In this randomized controlled trial, withholding prophylactic platelet transfusion in...
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