How Hormonal Biomarkers Impact Prognosis Within EC Molecular Subgroups
A recent study supported incorporating routine evaluation of ER and PR expression, in addition to molecular subgroup, in patients with endometrial cancer.
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Endometrial Cancer
Targeting Physical & Psychological Symptoms to Support Recovery After EC Surgery
Interventions targeting biobehavioral factors such as physical activity, sleep, and circadian rhythms may improve patient QOL following EC surgery.
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Protein Loss Predicts EC Prognosis
Loss of vimentin in endometrial cancer biopsies predicted metastases and worse survival, supporting its use in risk stratification and personalized treatment.
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Gaps Identified in EC Clinical Trial Enrollment
Recent study findings indicate Black patients with endometrial cancer are underrepresented in clinical trials despite higher rates of aggressive histologies.
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Robust Tool Improves Risk Stratification in EC
The prognostic nutritional index (PNI) was linked to various survival metrics in endometrial cancer, with low PNI predicting poorer outcomes.
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Panel Shows High Sensitivity in MMR Testing for EC
A 2-protein MSH6-PMS2 panel may be a cost-effective, reliable alternative to the 4-protein MMR immunohistochemistry panel in diagnosing MMR deficiency in endometrial cancer.
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Model Predicts Lymph Node Metastasis in EC
A clinical-radiomics model predicted lymph node metastasis in type I endometrial cancer with 98% accuracy, outperforming radiomics-only or clinical models.
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Lifestyle Counseling for Patients With EC: A Roadmap for Clinicians
A recent study outlined lifestyle counseling strategies to enhance adherence to healthy lifestyle recommendations for patients with endometrial cancer.
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How Tumor Stiffness Adds Value to Endometrial Cancer Assessment
Combining MR elastography with clinical radiological data improved the prediction of lymphovascular space invasion in patients with endometrial cancer.
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Endometrial Cancer Risk Greater in Women With PCOS
A research team from Denmark conducted a nationwide cohort study and found that women with polycystic ovary syndrome had increased risk for endometrial cancer.
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Integrating Endometrial Cancer Molecular Data With Pathologic Features
Researchers wrote it is essential to integrate molecular data with traditional pathologic features to perform accurate prognostication in endometrial cancer.
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Adding Pembrolizumab to Chemoradiotherapy Significantly Improves OS in Locally Advanced Cervical Cancer
Adding pembrolizumab to modern, high-quality chemoradiotherapy significantly improved overall survival in patients with locally advanced cervical cancer.
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Liquid Profiling Provides Actionable Results in Nearly 90% of Advanced EC Cases
A recent study found cell-free DNA liquid profiling accurate and useful in characterizing different types of endometrial cancer and guiding therapy selection.
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Conventional & Robotic-Assisted Laparoscopy Comparable
A study of patients with type 2 endometrial cancer found no differences in overall survival with conventional laparoscopy versus robot-assisted laparoscopy.
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Transvaginal Ultrasound Triage Strategy Unreliable for Black Women
Among Black patients, a significant proportion with endometrial cancer had endometrial thickness under the range of diagnostic thresholds for detection.
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Is Sentinel Lymph Node Biopsy Always Necessary?
A study found omitting sentinel lymph node biopsy is feasible in patients with lower stages of endometrial cancer since lymph node positivity tends to be low.
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Triglyceride-Glucose Index Predicts Risk, Progression
These findings suggest the triglyceride-glucose index as a potential predictive biomarker for endometrial carcinoma.
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MRI Effectively Predicts Lymphovascular Space Invasion
The findings of this study suggest that MRI has moderate diagnostic efficacy for LVSI status in EC.
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Predicting Endometrial Cancer Recurrence With a Deep Learning Model
A deep learning model called HECTOR stratified patients by determining the probability of endometrial cancer recurrence, which could have clinical implications.
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Supporting Adherence to Healthy Lifestyle Changes During Endometrial Cancer Care
Patients with endometrial cancer reported not receiving information about lifestyle improvements and behavior changes during their follow-up care.
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