BRCA2 Pathogenic Variants Linked to Secondary Cancers
In triple-negative breast cancer, patients with BRCA2 pathogenic variants had higher frequencies of bone and CNS metastases....
In triple-negative breast cancer, patients with BRCA2 pathogenic variants had higher frequencies of bone and CNS metastases....
An LDL “cholesterol paradox” exists in patients with heart failure and raises doubt with regard to safe statin use in patients with HF without diabetes. LDL cholesterol (LDL-C)—...
Management of cardiovascular risk factors in patients with chronic myeloid leukemia on TKI therapy is an attainable and feasible approach. In patients with chronic myeloid leuke...
In survivors of breast cancer, the influence of chronic pain on QOL persisted even after controlling for concurrent pain. Chronic pain remains highly prevalent among survivors o...
People with diabetes might need to exercise caution when it comes to long-term use of calcium supplements. Calcium supplement use to prevent osteoporotic fractures is common amo...
Patients with an infection before liver transplant had excellent survival outcomes despite requiring more complex post-transplant care....
Treatment for MS within 6 months of the first demyelinating event improved EDSS scores, disability progression, and conversion to secondary progressive MS....
In patients with kidney disease on hemodialysis, a wearable activity tracker paired with a feedback intervention increased daily step count over 12 weeks....
Decision making in advanced heart failure therapy allocation is subject to bias by race, sex, and ethnicity, a study of group dynamics has found....
Daily PrEP use, rather than on-demand dosing, may be better for young MSM due to their inability to predict sexual encounters accurately and consistently....
Researchers are working to overcome clinical trial challenges to explore genetic therapies for X-linked retinitis pigmentosa caused by RPGR and RP2 genes. Pathogenic variants in ...
Oral therapy for infective endocarditis demonstrated similar clinical efficacy compared with IV therapy and was associated with fewer adverse events....
One third of US adults with diabetes has early cardiovascular disease, which can be identified by two cardiac biomarkers. One in three adults with diabetes living in the United States...
Other breast cancer risk factors in addition to breast density should be considered when deciding whether to prescribe supplemental ultrasound screening....
In older adults with acute myeloid leukemia, the EHR-based frailty index is associated with the type of treatment received....
The study’s findings can help allergists identify those patients with peanut allergy who are experiencing a poorer QOL....
The decision to use weight loss pharmacotherapy for teenagers who have obesity should involve a personalized approach, specific to each patient....
The joint occurrence of SELs and PRLs, two MRI markers of chronic active lesions in MS, was linked to greater clinical progression in patients with MS. Approximately 15% to 30% of the...
A comprehensive assessment of new-onset epilepsy should include screening for psychiatric conditions, which can impact up to 50% of this patient population....
Telemedicine should be integrated into the current system as a routine service option for stable patients with SLE. The pandemic compelled medical professionals to stretch beyond conv...
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