Advertisement

Ovarian Cancer

[PARP INHIBITORS FOR ADJUVANT TREATMENT FOR OVARIAN CANCER].

Mar 19, 2020

Treatment for ovarian cancer has been challenging for many years. It is composed of debulking surgery and chemotherapy. During the first line of treatment most patients are sensitive to primary platin...

[Vertigo as the first manifestation of ovarian cancer].

Mar 19, 2020

Vertigo is a common complaint and may rarely be the presenting symptom of a paraneoplastic neurological syndrome (PNS).A 76-year-old woman presented at the ER with subacute cerebellar syndrome and sev...

lncRNA MIAT Regulates Cell Growth, Migration, and Invasion Through Sponging miR-150-5p in Ovarian Cancer.

Mar 19, 2020

MIAT (myocardial infarction-associated transcript) regulates cell proliferation, apoptosis, and metastasis in several cancers. In this study, the authors aimed to explore the role of MIAT in ovarian ...

Apoptosis-related gene expression can predict the response of ovarian cancer cell lines to treatment with recombinant human TRAIL alone or combined with cisplatin.

Mar 19, 2020

The objectives of this study were to determine the sensitivity of ovarian cancer (OC) cell lines (TOV-21G and SKOV-3) to cisplatin and to the recombinant human TRAIL (rhTRAIL), and to evaluate the exp...

GeneReader NGS System Is a Useful Sequencing Platform for Clinical Testing of and .

Mar 13, 2020

Although next-generation sequencing (NGS) is widely used for sequencing analysis, it involves a fragmented workflow along with complex bioinformatic analysis and interpretation. In this study, the pe...

Parity as a Prognostic Factor in Patients with Advanced-Stage Epithelial Ovarian Cancer.

Mar 13, 2020

This study aimed to determine the prognostic factors influencing the overall survival (OS) of Iranian women with epithelial ovarian cancer (EOC).Information about newly diagnosed patients with confirm...

Tumor-derived exosomes in the regulation of macrophage polarization.

Mar 13, 2020

This review focuses on exosomes derived from various cancer cells. The review discusses the possibility of differentiating macrophages in alternatively activated anti-inflammatory pro-tumorigenic M2 m...

Association of Germline Variant Status With Therapy Response in High-risk Early-Stage Breast Cancer: A Secondary Analysis of the GeparOcto Randomized Clinical Trial.

Mar 13, 2020

The GeparOcto randomized clinical trial compared the efficacy of 2 neoadjuvant breast cancer (BC) treatment regimens: sequential intense dose-dense epirubicin, paclitaxel, and cyclophosphamide (iddEPC...

Long non-coding RNA RHPN1-AS1 promotes tumorigenesis and metastasis of ovarian cancer by acting as a ceRNA against miR-596 and upregulating LETM1.

Mar 13, 2020

In recent decades, long non-coding RNAs (lncRNAs) have been reported as crucial functional regulators involved in ovarian cancer. In the present study, we explored how lncRNA RHPN1-AS1 influences the ...

Dietary fats promote inflammation in Wistar rats as well as induce proliferation, invasion of SKOV3 ovarian cancer cells.

Mar 12, 2020

The role of high fat diet (HFD) in ovarian cancer and its underlying mechanisms are poorly known. In current investigation, we investigated inflammatory and oncogenic effect of dietary fats in female...

CircRNA hsa_circ_0013958 may contribute to the development of ovarian cancer by affecting epithelial-mesenchymal transition and apoptotic signaling pathways.

Mar 12, 2020

CircRNA plays an important role in the development of tumors, but its mechanism of action in ovarian cancer is still unclear.The expression level of hsa_circ_0013958 in 45 pairs of ovarian cancer tiss...

KNDC1 Is a Predictive Marker of Malignant Transformation in Borderline Ovarian Tumors.

Mar 12, 2020

Few screening markers for malignant transformation in borderline ovarian tumors (BOT) have been clearly established. The kinase noncatalytic C-lobe domain containing 1 (KNDC1), a brain-specific Ras gu...

Astragalus polysaccharides inhibits ovarian cancer cell growth via microRNA-27a/FBXW7 signaling pathway.

Mar 12, 2020

Astragalus polysaccharide (APS), a natural anti-oxidant found in Astragalus membranaceus emerging as a novel anticancer agent, exerts antiproliferative and pro-apoptotic activity in various cancer cel...

Use of an Online Breast Cancer Risk Assessment and Patient Decision Aid in Primary Care Practices.

Mar 12, 2020

U.S. Preventive Services Task Force (USPSTF) recommendations for mammography screening, genetic counseling and testing for pathogenic mutations, and use of risk-reducing medications require assessme...

Risk factors for late-onset lower limb lymphedema after gynecological cancer treatment: A multi-institutional retrospective study.

Mar 09, 2020

Late-onset lower limb lymphedema (LLL) is a significant clinical challenge for physicians dealing with patients that undergo treatment involving the pelvic cavity. We aimed to clarify the prevalence o...

The ADNEX model to triage adnexal masses: An external validation study and comparison with the IOTA two-step strategy and subjective assessment by an experienced ultrasound operator.

Mar 09, 2020

The ADNEX (Assessment of Different NEoplasias in the adneXa) model was developed using parameters collected by experienced (level III) ultrasound examiners. Our primary aim was to externally validate ...

The Emerging Role of Neutral Argon Plasma (PlasmaJet) in the Treatment of Advanced Stage Ovarian Cancer: A Systematic Review.

Mar 05, 2020

. To evaluate the contribution of PlasmaJet application in achieving optimal cytoreduction in advanced ovarian cancer. . We systematically searched for articles published up to June 2019 using MEDLINE...

Prophylactic salpingectomy for prevention of ovarian cancer at the time of elective laparoscopic cholecystectomy.

Mar 05, 2020

Most serous ovarian cancers are now understood to originate in the fallopian tubes. Removing the tubes (salpingectomy) likely reduces the risk of developing high-grade serous ovarian cancer. Numerous ...

Laboratory predictors of survival in ovarian cancer.

Mar 05, 2020

To relate disease-free survival and overall survival with type I and type II ovarian cancer and preoperative laboratory parameters biomarkers.A retrospective study was carried out based on the collect...

The Cost-Effective Preparation of Green Fluorescent Carbon Dots for Bioimaging and Enhanced Intracellular Drug Delivery.

Mar 05, 2020

Doxorubicin entrapped carbon dots (DOX-CDs) were prepared for bioimaging and enhanced intracellular drug delivery. The CDs were synthesized via the hydrothermal method using citrate and urea under 200...

SUBSPECIALTIES

Advertisement