Endoplasmic Reticulum Stress Proteins in Ovarian Carcinoma
Epithelial ovarian cancer (EOC) is a leading cause of cancer-related mortality in the United...
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Hematology/Oncology
microRNA-141-3p-containing small extracellular vesicles derived from epithelial ovarian cancer cells promote endothelial cell angiogenesis through activating the JAK/STAT3 and NF-κB signaling pathways.
Paracrine signaling between tumor and surrounding stromal cells is critical for the maintenance of...
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Synergistic Antitumor Effects in Drug-Resistant Ovarian Cancer
Despite the promising anticancer effects of kinesin spindle protein (KSP) inhibition, functional...
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Knockdown of enhancer of rudimentary homolog inhibits proliferation and metastasis in ovarian cancer by regulating epithelial-mesenchymal transition.
Ovarian cancer (OC) is the deadliest gynecological malignancy. The pathogenesis of molecular in...
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Loss of hnRNPA2B1 inhibits malignant capability and promotes apoptosis via down-regulating Lin28B expression in ovarian cancer.
Ovarian cancer has the highest mortality rate among all gynecological cancers with its pathogenic...
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Coping with Fear of Cancer Recurrence Among Ovarian Cancer Survivors
Fear of cancer recurrence (FCR) is a paramount concern among ovarian cancer survivors. Evidence...
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Long non-coding RNA TTN-AS1 promotes tumorigenesis of ovarian cancer through modulating the miR-139-5p/ROCK2 axis.
Long non-coding RNA (lncRNA) TTN antisense RNA 1 (TTN-AS1) was reported to be crucial modulators...
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Histological Tumor Type is Associated with One-Year Cause-Specific Survival in Women with Stage III-IV Epithelial Ovarian Cancer: A Surveillance, Epidemiology, and End Results (SEER) Database Population Study, 2004-2014.
BACKGROUND The prognosis of epithelial ovarian cancer (EOC) remains poor. Cause-specific survival...
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Poor Perfusion of Microvasculature in Peritoneal Metastases of Ovarian Cancer
Most women with epithelial ovarian cancer (EOC) suffer from peritoneal carcinomatosis upon first...
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The m6A reader YTHDF1 promotes ovarian cancer progression via augmenting EIF3C translation.
N 6-Methyladenosine (m6A) is the most abundant RNA modification in mammal mRNAs and increasing...
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Proteomic analysis of degradation ubiquitin signaling by ubiquitin occupancy changes responding to 26S proteasome inhibition.
Ubiquitination is a post-translational modification where ubiquitin is covalently attached to...
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Genomic Signatures of Immune Activation Predict Outcome in Advanced Stages of Ovarian Cancer and Basal-Like Breast Tumors.
There is an unmet need for new therapies in metastatic ovarian cancer and basal-like breast cancer...
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Muscle loss during primary debulking surgery and chemotherapy predicts poor survival in advanced-stage ovarian cancer.
Sarcopenia is commonly observed in patients with advanced-stage epithelial ovarian cancer (EOC)....
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Identification three LncRNA prognostic signature of ovarian cancer based on genome-wide copy number variation.
Ovarian cancer is one of the most common malignant tumors of the female reproductive system, which...
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Overcoming Resistance to Platinum-Based Drugs in Ovarian Cancer by Salinomycin and Its Derivatives-An In Vitro Study.
Polyether ionophore salinomycin (SAL) and its semi-synthetic derivatives are recognized as very...
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Strong Evidences of the Ovarian Carcinoma Risk in Women after IVF Treatment
In-vitro fertilization (IVF) has been very popular since the birth of the first...
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Should MMMT still be treated with adjuvant taxane-based combination chemotherapy?
Malignant mixed Mullerian tumors of endometrial (MMMT-E) and ovarian (MMMT-O) origin are...
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Trabectedin (Yondelis®) as a Therapeutic Option in Gynecological Cancers: A Focus on its Mechanisms of Action, Clinical Activity, and Genomic Predictors of Drug Response.
The use of predictive biomarkers provides potential individualized cancer therapeutic options to...
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PRMT1 Is Recruited via DNA-PK to Chromatin Where It Sustains the Senescence-Associated Secretory Phenotype in Response to Cisplatin.
Protein arginine methyltransferase 1 (PRMT1) is overexpressed in various human cancers and linked...
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Hyperthermic intraperitoneal chemotherapy for ovarian cancer: The heat is on.
Patients with advanced epithelial ovarian cancer have a high incidence of peritoneal disease...
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