Cooperation therapy between anti-growth by photodynamic-AIEgens and anti-metastasis by small molecule inhibitors in ovarian cancer.
Metastasis is one of the main causes of death and treatment failure in ovarian cancer. Some small...
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Hematology/Oncology
Influence of Geographical and Seasonal Variations on Carbazole Alkaloids Distribution in : Deciding Factor of Its and Efficacies against Cancer Cells.
is a well-known Indian medicinal herb, and a carbazole alkaloid (mahanine) from this plant causes...
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Magnesium intake and primary liver cancer incidence and mortality in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial.
Epidemiological studies on magnesium intake and primary liver cancer (PLC) are scarce, and no...
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Role of Frozen Section in Surgical Management of Ovarian Neoplasm.
Cancers of the adnexae, including ovarian and fallopian tube, constitute the eighth most common...
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Comparison of BRCA versus non-BRCA germline mutations and associated somatic mutation profiles in patients with unselected breast cancer.
The data on the phenotypes associated with some rare germline mutations in Chinese breast cancer...
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The contribution of germline predisposition gene mutations to clinical subtypes of invasive breast cancer from a clinical genetic testing cohort.
The germline cancer predisposition genes associated with increased risk of each clinical subtype...
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Improved stability of siRNA-loaded lipid nanoparticles prepared with a PEG-monoacyl fatty acid facilitates ligand-mediated siRNA delivery.
Peptide modification is a popular strategy for developing an active targeting lipid nanoparticle...
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Detection of BRCA1/2 Large Genomic Rearrangement including BRCA1 Promoter-Region Deletions using Next-Generation Sequencing.
Germline mutations in BRCA1 and BRCA2 (BRCA1/2) have been conventionally analyzed by Sanger...
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ABCG2 Overexpression Contributes to Pevonedistat Resistance.
MLN4924 (pevonedistat) is a first-in-class NEDD8-activating enzyme (NAE) inhibitor in clinical...
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Vitamin D Exposure and Ovarian Cancer Risk and Prognosis.
Given the poor prognosis of ovarian cancer and limited population-level strategies for early...
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TGF-β1 fucosylation enhances the autophagy and mitophagy via PI3K/Akt and Ras-Raf-MEK-ERK in ovarian carcinoma.
Transforming growth factor-β, a cell secretion factor of the TGF-β superfamily, is involved in the...
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The DNA cytosine deaminase APOBEC3B is a molecular determinant of platinum responsiveness in clear cell ovarian cancer.
Clear cell ovarian carcinoma (CCOC) is an aggressive disease that often demonstrates resistance to...
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The miR-34 Family and its Clinical Significance in Ovarian Cancer
The tumor suppressor miR-34 family is transcriptionally induced by p53. Clinical significance of...
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Sharing Real-World Experiences to Optimize Management of Olaparib Toxicities
Olaparib is the first poly(ADP-ribose) polymerase inhibitor approved as maintenance therapy of...
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Circular RNA PVT1 enhances cell proliferation but inhibits apoptosis through sponging microRNA-149 in epithelial ovarian cancer.
This study aimed to investigate the influence of circular RNA PVT1 (circ-PVT1) on epithelial...
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Oral Metronomic Chemotherapy for Recurrent & Refractory Epithelial Ovarian Cancer
Advanced epithelial ovarian cancer (EOC) is associated with dismal outcome and progression-free...
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LncRNA TTN-AS1 acts as sponge for miR-15b-5p to regulate FBXW7 expression in ovarian cancer.
Emerging evidence showed that long noncoding RNA (lncRNA) plays crucial roles in regulating...
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Ubiquitin-specific protease 14 regulates ovarian cancer cisplatin-resistance by stabilizing BCL6 oncoprotein.
Ubiquitin-specific protease 14 (USP14) is one of the three proteasome-associated deubiquitinating...
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Endoplasmic Reticulum Stress Proteins in Ovarian Carcinoma
Epithelial ovarian cancer (EOC) is a leading cause of cancer-related mortality in the United...
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microRNA-141-3p-containing small extracellular vesicles derived from epithelial ovarian cancer cells promote endothelial cell angiogenesis through activating the JAK/STAT3 and NF-κB signaling pathways.
Paracrine signaling between tumor and surrounding stromal cells is critical for the maintenance of...
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