Noninferiority of Reduced-Dose Anticoagulants Unproven for Recurrent VTE
Reduced-dose anticoagulants for extended VTE treatment were associated with more recurrent events but less bleeding, according to recent findings.
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ICYMI
Evaluating Auto-HCT for MCL With Undetectable Residual Disease
Auto-HCT showed no survival benefit over maintenance therapy alone in patients with mantle cell lymphoma with undetectable MRD in first complete remission.
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Does Emphysema Impact Treatment Response in Severe Asthma?
Emphysema did not significantly affect the response to systemic therapy in patients with severe asthma, according to a recent retrospective study.
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Predicting Early Versus Late Response to Treatment in SEA
Early improvement was linked to lower baseline FEV1 and higher eosinophils in severe eosinophilic asthma, while late improvement was linked to high ACT scores.
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Steep Increase in Event-Driven PrEP Use
Researchers found a steep increase in even-driven PrEP use among cisgender gay, bisexual, and other men who have sex with men.
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Considerable Scale-Up Needed to Meet 2025 HIV PrEP Goals
About 3.5 million persons used PrEP in 2023 globally, which was far below the goal of 21.2 million set for 2025.
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USPSTF on Vitamin D for Preventing Fractures & Falls
The US Preventive Services Task Force issued a class D recommendation against vitamin D supplementation for preventing fractures and falls in older adults.
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Most Adults Want PCPs to Ask About Mental Health
In a survey conducted by West Health and Gallup, seven in 10 US adults said they wanted to discuss physical and mental health with primary care professionals.
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Association Between Diabetic Nephropathy, Gut Microbiota Identified
A potential causal association was substantiated between specific gut microbiota and diabetic nephropathy in a recently published study.
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Female Hormones May Protect Against AKI Hospitalization
Higher risk during hospitalization for AKI in males and lower risk for postmenopausal women on estrogen suggest female sex hormones may protect against AKI.
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Novel Nomogram Predicts Postop ECRSwNP Recurrence
A new nomogram model incorporates risk factors for postoperative recurrence in patients with ECRSwNP to identify patients at high risk for ECRSwNP recurrence.
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Predicting CRSwNP Recurrence Post-Surgery
Poor outcomes in CRSwNP after ESS are linked to asthma, frontal sinus involvement, high blood eosinophils, and elevated LM system and NPS scores.
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Vitamin D Supplements May Lower BP in Older Adults Who Are Overweight
Vitamin D supplementation led to sizable declines in systolic and diastolic BP in older adults who are overweight, including those with hypertension.
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US Obesity Rate Drops for the First Time in a Decade
Following increases in the country’s mean BMI from 2013 to 2022, mean BMI in the United States declined in 2023, most notably in older adults and women.
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AI Accurately Diagnoses & Stages COPD
AI-based COPD diagnosis and staging using CT imaging achieved moderate to good agreement with reference standards and improved by including clinical data.
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How Useful Is FeNO for Guiding Asthma Management?
A recent systematic review showed FeNO-guided asthma management reduced exacerbations but showed limited benefits for severe outcomes, lung function, or QOL.
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RA Associated With Significant Economic & Human Burdens
Rheumatoid arthritis was associated with higher healthcare costs and reduced QOL in US adults, with increased assistance needed for daily activities.
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AMD Linked to Higher RA Risk
Age-related macular degeneration was linked to an increased risk for rheumatoid arthritis, with higher risks in people who did not have visual disability.
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Model Predicts Stillbirths Using Preeclampsia Screening Data
A new study showed that a first-trimester screening model combining maternal, biophysical, and biochemical markers effectively predicted stillbirths.
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Preeclampsia’s Impact on Maternal & Neonatal Outcomes
Preeclampsia poses significant maternal and neonatal risks, with long-term complications like chronic diseases in mothers and developmental issues in children.
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