Jan 04, 2021

This review provides insights into the mechanism underlying the pathogenesis of myopia and potential targets for clinical intervention. Although the etiology of myopia involves both environmental and ...

Jan 04, 2021

Myopic maculopathy and glaucoma belong to the most common causes of irreversible blindness worldwide and, having an ocular axial elongation as one of their main risk factors, can occur together. The d...

Jan 04, 2021

Evaluation of the demographic profile, clinical features, topographic, biomechanical and aberrometric characteristics in pediatric keratoconus (KC).Cross-sectional study METHODS: Cases with KC aged &l...

Dec 31, 2020

The purpose of this study was to perform a detailed longitudinal phenotyping of X-linked retinitis pigmentosa (RP) caused by mutations in the RPGR gene during a long follow-up period.An Italian cohort...

Dec 31, 2020

To compare the value of pre-treatment axial elongation (AE) and changes in refractive sphere (M change) for predicting the success in orthokeratology (ortho-k), in order to better identify suitable ca...

Dec 31, 2020

Complications from pathologic myopia (PM) are a major cause of visual impairment and blindness. However, an efficient clinical therapeutic strategy for PM is still lacking. The aim of this study was t...

Dec 24, 2020

To propose the Myopic Traction Maculopathy (MTM) management Table, based on the MTM Staging System (MSS).A retrospective review of 157 eyes affected by MTM, operated with pars plana vitrectomy (PPV), ...

Dec 24, 2020

To describe a clinical picture resembling classic multiple evanescent white dot syndrome (MEWDS) potentially triggered by previous or concurrent, apparently unrelated, ocular events and to provide a l...

Dec 24, 2020

CTNNB1 (MIM 116806) encodes beta-catenin, an adherens junction protein that supports the integrity between layers of epithelial tissue and mediates intercellular signaling. Recently, various heterozyg...

Dec 21, 2020

Refractive errors (conditions in which the eye fails to focus objects accurately on the retina due to defects in the refractive system), are the most common cause of visual impairment. Myopia, hyperop...

Dec 21, 2020

Postoperative suprachoroidal hemorrhage is an infrequent but devastating complication after non-valved aqueous drainage implant surgery and demonstrated a bimodal distribution. The final outcomes of e...

Dec 21, 2020

We investigate the efficacy and safety of intravitreal injection (IVI) of anti-vascular endothelial growth factor agents and laser photocoagulation (LPC) for retinopathy of prematurity (ROP). We perfo...

Dec 17, 2020

Collagen cross-linking of the sclera is a promising approach to strengthen scleral rigidity and thus to inhibit eye growth in progressive myopia. Additionally, cross-linking might inhibit degrading pr...

Dec 17, 2020

Myopia is the leading cause of refractive errors. As its pathogenesis is poorly understood, we determined if the retinal VIP-VIPR2 signalling pathway axis has a role in controlling signalling output t...

Dec 17, 2020

Homocystinuria due to cystathionine β-synthase (CBS) deficiency, the most frequent inborn error of sulfur amino acid metabolism, is characterized biochemically by severely elevated homocysteine (Hcy)...

Dec 14, 2020

To evaluate the efficacy of individualized corneal patching using a minimal graft for corneal trauma combined with tissue defects.Fifteen eyes (15 patients) were enrolled in this study, including 8 ey...

Dec 14, 2020

In glaucoma, retinal ganglion cells degenerate progressively, leading to visual field loss and blindness. Presently, the only treatment strategy for glaucoma is lowering the intraocular pressure. Howe...

Dec 14, 2020

Atropine, a non-selective muscarinic antagonist, is known to slow down myopia progression in human adolescents and in several animal models. However, its underlying molecular mechanism is unclear. The...

Dec 10, 2020

The effect and safety of atropine on delaying the progression of myopia has been extensively studied, but its optimal dose is still unclear. Therefore, the purpose of this meta-analysis is to systemat...

Dec 10, 2020

To determine factors associated with non-adherence to contact lens wear schedule involving single vision and myopia control contact lenses in children.Data from 379 children enrolled in a prospective,...