Targeting the Nasal Microbiome in CRSwNP: A Novel Treatment Strategy
The nasal microbiome in CRSwNP, which differs from that of healthy controls, may provide an opportunity to personalize treatment, according to researchers.
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Nasal Polyps
Bilateral CRSwNP Linked to Unique Risks Versus Unilateral Cases
Bilateral versus unilateral cases of chronic rhinosinusitis with nasal polyps have notable clinical and laboratory differences that impact patient outcomes.
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Elevated TSLP & IL-4 in CRSwNP Decrease Postoperative Sinonasal QOL
TSLP and IL-4 were elevated in patients with CRSwNP and linked to decreased sinonasal QOL benefit after functional endoscopic sinus surgery.
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MS4A2 Shows Promise as Refractory eCRS Therapeutic Target
A recent study identified MS4A2 as a key molecule in refractory eosinophilic chronic rhinosinusitis, highlighting MS4A2 as a potential therapeutic target.
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Low Vitamin D in Patients With Nasal Polyps: A Biomarker & Potential Treatment Target
Low vitamin D in patients with nasal polyps negatively correlated with several markers, including Lund-Mackay and total nasal polyp scores.
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Tissue Eosinophil Count Reliable in Managing CRSwNP
Recent study findings support the reliability of tissue eosinophil count from a single biopsy for clinical use in managing CRSwNP.
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Model Differentiates Nasal Polyps From Inverted Papilloma
Study results suggest that deep learning based on CT imaging is promising for distinguishing nasal polyps from inverted papilloma lesions.
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Interviewing Patients on PROMs Improves CRSwNP Outcomes
Interviewing patients on PROMs may improve outcomes in chronic rhinosinusitis with nasal polyps, according to findings from a recent interview study.
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Mast Cells: An Emerging Treatment Target in Chronic Rhinosinusitis With Nasal Polyps
Emerging research shows mast cells play a role in the etiology of chronic rhinosinusitis with nasal polyps and may be a new treatment target for the condition.
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Predicting CRSwNP Recurrence Post-Surgery
Poor outcomes in CRSwNP after ESS are linked to asthma, frontal sinus involvement, high blood eosinophils, and elevated LM system and NPS scores.
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Novel Nomogram Predicts Postop ECRSwNP Recurrence
A new nomogram model incorporates risk factors for postoperative recurrence in patients with ECRSwNP to identify patients at high risk for ECRSwNP recurrence.
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MRI Beneficial for Differentiating Between Tissue Types in CRSwNP
MRI and Apparent Diffusion Coefficient values enable differentiation between edematous and fibrotic tissue in chronic rhinosinusitis with nasal polyps.
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