Given the rising prevalence of cognitive impairment in COPD, researchers have called for increased efforts to identify risk factors and intervene earlier. Some experts suggest that COPD should no longer be defined as a single disease with various...
Neurology
RELEVANT ARTICLES IN Neurology
AAN: Tavapadon as Adjunct to Levodopa Ups Daily ON Time in Parkinson Disease
AAN: Tavapadon as Adjunct to Levodopa Ups Daily ON Time in Parkinson Disease
TUESDAY, April 8, 2025 (HealthDay News) -- For patients with Parkinson disease with motor fluctuations, the oral once-daily, selective D1/D5 partial dopamine agonist tavapadon as an adjunct to levodopa increases total daily ON time versus placebo, according to a...
Comparing Andexanet and PCCs for Hemostasis in ICrH Treatment
Comparing Andexanet and PCCs for Hemostasis in ICrH Treatment
The following is a summary of “Reversal of Factor Xa Inhibitor-Related Intracranial Hemorrhage: A Multicenter, Retrospective, Observational Study Comparing the Efficacy and Safety of Andexanet and Prothrombin Complex Concentrates,” published in the April 2025 issue...
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ACP: Guidance Provided for Use of Cannabis in Chronic Noncancer Pain Management
ACP: Guidance Provided for Use of Cannabis in Chronic Noncancer Pain Management
MONDAY, April 7, 2025 (HealthDay News) -- In a best practice guideline issued by the American College of Physicians and published online April 4 in the Annals of Internal Medicine, advice is presented for clinicians regarding the benefits and harms of cannabis or...
CRISPRi-based screen of autism spectrum disorder risk genes in microglia uncovers roles of ADNP in microglia endocytosis and synaptic pruning.
CRISPRi-based screen of autism spectrum disorder risk genes in microglia uncovers roles of ADNP in microglia endocytosis and synaptic pruning.
Autism Spectrum Disorders (ASD) are a set of neurodevelopmental disorders with complex biology. The identification of ASD risk genes from exome-wide association studies and de novo variation analyses has enabled mechanistic investigations into how ASD-risk genes...
Backbone-mediated weakening of pairwise interactions enables percolation in peptide-based mimics of protein condensates.
Backbone-mediated weakening of pairwise interactions enables percolation in peptide-based mimics of protein condensates.
Biomolecular condensates formed by intrinsically disordered proteins (IDPs) are semidilute solutions. These can be approximated as solutions of blob-sized segments, which are peptide-sized motifs. We leveraged the blob picture and molecular dynamics simulations to...
AAN: Tavapadon as Adjunct to Levodopa Ups Daily ON Time in Parkinson Disease
AAN: Tavapadon as Adjunct to Levodopa Ups Daily ON Time in Parkinson Disease
TUESDAY, April 8, 2025 (HealthDay News) -- For patients with Parkinson disease with motor fluctuations, the oral once-daily, selective D1/D5 partial dopamine agonist tavapadon as an adjunct to levodopa increases total daily ON time versus placebo, according to a...
Comparing Andexanet and PCCs for Hemostasis in ICrH Treatment
Comparing Andexanet and PCCs for Hemostasis in ICrH Treatment
The following is a summary of “Reversal of Factor Xa Inhibitor-Related Intracranial Hemorrhage: A Multicenter, Retrospective, Observational Study Comparing the Efficacy and Safety of Andexanet and Prothrombin Complex Concentrates,” published in the April 2025 issue...
ACP: Guidance Provided for Use of Cannabis in Chronic Noncancer Pain Management
ACP: Guidance Provided for Use of Cannabis in Chronic Noncancer Pain Management
MONDAY, April 7, 2025 (HealthDay News) -- In a best practice guideline issued by the American College of Physicians and published online April 4 in the Annals of Internal Medicine, advice is presented for clinicians regarding the benefits and harms of cannabis or...
CRISPRi-based screen of autism spectrum disorder risk genes in microglia uncovers roles of ADNP in microglia endocytosis and synaptic pruning.
CRISPRi-based screen of autism spectrum disorder risk genes in microglia uncovers roles of ADNP in microglia endocytosis and synaptic pruning.
Autism Spectrum Disorders (ASD) are a set of neurodevelopmental disorders with complex biology. The identification of ASD risk genes from exome-wide association studies and de novo variation analyses has enabled mechanistic investigations into how ASD-risk genes...
Backbone-mediated weakening of pairwise interactions enables percolation in peptide-based mimics of protein condensates.
Backbone-mediated weakening of pairwise interactions enables percolation in peptide-based mimics of protein condensates.
Biomolecular condensates formed by intrinsically disordered proteins (IDPs) are semidilute solutions. These can be approximated as solutions of blob-sized segments, which are peptide-sized motifs. We leveraged the blob picture and molecular dynamics simulations to...
CONDITION SPOTLIGHTS
Condition Spotlight: Tardive Dyskinesia
A collection of feature articles, study abstracts, and additional resources all focused on tardive dyskinesia (TD).
ACTRIMS Forum 2024: Multiple Sclerosis
The latest news from ACTRIMS Forum 2024 focused on multiple sclerosis, including abstracts, features, and helpful conference information.
AAN 2023 Fall Conference: MS
The latest news from AAN 2023 Fall Conference on multiple sclerosis (MS), including featured articles and information about the conference.
2023 NACLC: NSCLC
The latest news from 2023 NACLC on non-small cell lung cancer (NSCLC), including abstracts, featured articles, and information about the conference.
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Students Celebrate Matching—Now the Real Work Begins
Students Celebrate Matching—Now the Real Work Begins
As new physicians match, the system they enter needs repair.
Shannon, Part 2: A Screwy Situation
Shannon, Part 2: A Screwy Situation
This medical fiction takes place in a chaotic ED where a nurse is assigned an impossible case. As the patient defies all odds, a shocking crime unfolds.
Addressing Acute Pain & Related Challenges: Will Recent FDA Approval of a Novel Non-Opioid Analgesic Be a Game Changer?
Addressing Acute Pain & Related Challenges: Will Recent FDA Approval of a Novel Non-Opioid Analgesic Be a Game Changer?
FDA approval of a novel non-opioid analgesic will hopefully address the needs of many patients with acute pain and improve clinical outcomes and QOL.
Medical, Psychiatric Comorbidities Common in New-Onset & Incident Epilepsy
This course discusses a study that was looking to find which chronic conditions may be risk factors for epilepsy onset in older adults.
Key Aspects of Memory in MS Improved With Cognitive Rehab
This course discusses a study that identified acceptability, adherence, and enrollment criteria for cognitive rehabilitation interventions in patients with MS.
Poor Sleep Increases Migraine-Related Pain & Mental Health Burden
This course discusses a study that explored the relationship between sleep quality and risks for developing migraine, as well as gender and age differences.
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How Physicians Can Stay Up-to-Date on the Legal Status, FDA Approval, & Safety of Cannabis Use
How Physicians Can Stay Up-to-Date on the Legal Status, FDA Approval, & Safety of Cannabis Use
Cannabis use is rising for medical benefits, but physicians call for more research and clearer regulations due to potential risks.
How Effective Revenue Cycle Management Can Create a Successful System for Collecting Payments
How Effective Revenue Cycle Management Can Create a Successful System for Collecting Payments
The healthcare industry has undergone a number of significant alterations that have added to the already challenging task of revenue-cycle management.
Key Results From the 2025 NRMP Match
Key Results From the 2025 NRMP Match
The National Resident Matching Program (NRMP) shared results from the 2025 Main Residency Match, the largest in its history.
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