New prophylactics for migraine targeting CGRP have emerged. Real world data are important to obtain comprehensive understanding of response. We assessed consistency of response to erenumab, ...
Migraine is a complex neurological disorder affecting approximately 12% of the population. The pathophysiology is not yet fully understood, however the clinical features of the disease, such...
Health economic evaluations support health-care decision-making by providing information on the costs and consequences of health interventions. No universally accepted methodology exists for...
Clinical trials for calcitonin gene-related peptide (CGRP) inhibitors excluded the concomitant use of onabotulinumtoxinA; thus, there is a lack of efficacy and safety data of the combined th...
Globally, headache disorders are an important cause of disability in adults. As many types of headache (eg, migraine, tension-type and medication-overuse) are more common in women and have p...
Migraines are commonly associated with a visual aura that has a characteristic clinical presentation. Cortical lesions within or in close proximity to the retrochiasmal visual pathways may a...
Among all headache disorders, migraine has the highest prevalence during gestation. The majority of migraineurs experience improvement during pregnancy, but a few may experience migraine for...
The cranial meninges, comprised of the dura mater, arachnoid, and pia mater, are thought to primarily serve structural functions for the nervous system. For example, they protect the brain f...
“Tinnitus is a condition that affects approximately 10% of the adult population in the United States and can diminish one’s quality of life,” explains Hamid R. Djalilian, MD. “To dat...
Migraine involves neurovascular, functional, and anatomical alterations. Migraine sufferers experience an intense unilateral and pulsatile headache frequently accompanied with vomiting, naus...
We sought to evaluate the factors associated with better outcomes for emergency department (ED) patients treated for primary headache.This was a health records review of consecutive patients...
Out of many disease conditions suffered by mankind since ancient ages, Migraine holds a significant position. It is derived from the word "hemi-crania" and is a type of primary headache. Thi...
Headaches are among the most prevalent and disabling neurologic disorders and there are several unmet needs as current pharmacological options are inadequate in treating patients with chroni...
This study aimed to evaluate ocular vascularity in young adult migraine patients with visual aura and without visual aura.The study included 30 patients with migraine with visual aura (MWVA)...
Excessive sensitivity to certain visual stimuli (cortical hyper-excitability) is associated with a number of neurological disorders including migraine, epilepsy, multiple sclerosis, autism a...
Including recent FDA approvals of several calcitonin gene-related peptide (CGRP) receptor antagonists, advances in pharmacologic therapy for the prevention of migraine continue to emerge. In...
To summarize the unique aspects of managing headache in gender minorities and current research in this area including the potential relationship between gender-affirming hormone therapy (GAH...
We conducted a randomized trial among emergency department patients with migraine to determine the relative impact on migraine-associated symptoms of hydromorphone, an opioid, versus prochlo...
Erenumab is a human anti-calcitonin gene-related peptide receptor monoclonal antibody approved for migraine prevention. We sought to further assess the temporal patterns of response to erenu...
“Migraine, which affects more than 1 billion people worldwide, is one of the leading causes of disability in people younger than 50,” says Keisuke Suzuki, MD, PhD. “In addition to mode...
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